Zobrazeno 1 - 10
of 39
pro vyhledávání: '"E N, Bychkova"'
Autor:
E. E. Bykov, E. P. Mirchink, E. B. Isakova, E. N. Bychkova, E. N. Olsufyeva, A. N. Tevyashova
Publikováno v:
Антибиотики и Химиотерапия, Vol 62, Iss 3-4, Pp 10-17 (2020)
Antibacterial activity of hybrid antibiotics vancomycin-azithromycin (C11, C12-carbonate) and eremomycin-azitromycin (C11, C12-carbonate) was evaluated. Quantum chemical calculations of complexes of hybrid antibiotics with a model tripeptide ligand a
Externí odkaz:
https://doaj.org/article/6c541ce8cc114b3bae93328cdf91c18f
Publikováno v:
Антибиотики и Химиотерапия, Vol 60, Iss 9-10, Pp 7-11 (2020)
Amidation of the end carboxyl group of eremomycin and vancomycin by pinacolinic 4- or 3-amino methyl phenyl boron acids esters in the presence of the condensing reagent PyBOP resulted in formation of novel carboxamides of the antibiotics (IIIa-VIa).
Externí odkaz:
https://doaj.org/article/28dec7c29e9241d79f6dea09ad8de075
Publikováno v:
Pharmaceutical Chemistry Journal. 53:1018-1021
Amphotericin B (AmB) remains a drug of first choice for treatment of most severe mycoses despite significant toxicity and solubility problems. Screening of a series of new semisynthetic polyene macrolide derivatives identified AmB N-(2-aminoethyl)ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47bea7dcdad55ab67890826530d0d056
https://doi.org/10.1007/s11094-020-02116-y
https://doi.org/10.1007/s11094-020-02116-y
Autor:
Anna N. Tevyashova, E. N. Bychkova, S. E. Solov’eva, Andrey E. Shchekotikhin, Natalya E Grammatikova
Publikováno v:
Pharmaceutical Chemistry Journal. 53:976-980
The search for new antifungal agents with improved chemotherapeutic properties has produced the semisynthetic polyene macrolide amphotericin B derivative amphamide, which has a number of clear advantages over the starting antibiotic. The development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24491d33243013362447ced09575846b
https://doi.org/10.1007/s11094-020-02108-y
https://doi.org/10.1007/s11094-020-02108-y
Publikováno v:
материалы конференции.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55a00167ae1c771c387253aeabb7b524
https://doi.org/10.19163/medchemrussia2021-2021-146
https://doi.org/10.19163/medchemrussia2021-2021-146
Publikováno v:
Pharmaceutical Chemistry Journal. 52:930-935
Methods for selective chemical modification of the antitumor antibiotic olivomycin A(OA) were developed at GINA. The compound olivamide with advantages over starting OA was selected from series of OA analogs. The goal of the present work was to devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e4774de6d1799a71eff29135e6c65fa
https://doi.org/10.1007/s11094-019-01928-x
https://doi.org/10.1007/s11094-019-01928-x
Autor:
Anna N. Tevyashova, George V. Zatonsky, Evgeny E. Bykov, Svetlana E. Solovieva, Olga S. Ostroumova, Treshchalin Ivan D, Andrey E. Shchekotikhin, E. R. Pereverzeva, Elena B. Isakova, Natalia E. Grammatikova, Elena P. Mirchink, Svetlana S. Efimova, E. N. Bychkova
Publikováno v:
ACS infectious diseases. 6(8)
Amphotericin B (AmB, 1) is the drug of choice for treating the most serious systemic fungal or protozoan infections. Nevertheless, its application is limited by low solubility in aqueous media and serious side effects such as infusion-related reactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cda8a63f06578ce2dd7dccf977575d1
https://pubmed.ncbi.nlm.nih.gov/32598131
https://pubmed.ncbi.nlm.nih.gov/32598131
Eremomycin pyrrolidide: a novel semisynthetic glycopeptide with improved chemotherapeutic properties
Autor:
E. N. Bychkova, Ivan D. Treshalin, Andrey V. Dekhnich, Elena P. Mirchink, Evgenia N Olsufyeva, Maria N. Preobrazhenskaya, Mikhail G Chernobrovkin, Elena B. Isakova, Andrey E. Shchekotikhin, E. R. Pereverzeva, Roman S. Kozlov
Publikováno v:
Drug Design, Development and Therapy. 12:2875-2885
Evgenia N Olsufyeva,1 Andrey E Shchekotikhin,1,2 Elena N Bychkova,1 Eleonora R Pereverzeva,1 Ivan D Treshalin,1 Elena P Mirchink,1 Elena B Isakova,1 Mikhail G Chernobrovkin,3 Roman S Kozlov,4 Andrey V Dekhnich,4 Maria N Preobrazhenskaya1,† 1Gause I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7c79871fed548796c58b17e15d4493
https://doi.org/10.2147/dddt.s173923
https://doi.org/10.2147/dddt.s173923
Autor:
E. N. Bychkova, Ilya A. Osterman, Réka Erdei, Gyula Batta, Anna N. Tevyashova, Alexander M. Korolev, Elena B. Isakova, Zsolt Szücs, Elena P. Mirchink
One of the promising directions of the combined approach is the design of dual-acting antibiotics - heterodimeric structures on the basis of antimicrobial agents of different classes. In this study a novel series of azithromycin-glycopeptide conjugat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0127ae3d01e60af3e27529856ebe826c
Publikováno v:
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 60(9-10)
Amidation of the end carboxyl group of eremomycin and vancomycin by pinacolinic 4- or 3-amino methyl phenyl boron acids esters in the presence of the condensing reagent PyBOP resulted in formation of novel carboxamides of the antibiotics (IIIa-VIa).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::132e18cfc9eb9acd9b15c2db1fbb50f2
https://pubmed.ncbi.nlm.nih.gov/27141632
https://pubmed.ncbi.nlm.nih.gov/27141632