Zobrazeno 1 - 10
of 73
pro vyhledávání: '"E Mechetner"'
Publikováno v:
Russian Journal of General Chemistry. 84:345-356
Due to a unique structure of tumors, TNT antibodies can bind with a great number of target cells in the hypoxic core of the injury zone. Long-standing laboratory and clinical research gave evidence for the utility of histone/DNA complexes as stable i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::122c538c5d631194c56831d28a303804
https://doi.org/10.1134/s1070363214020364
https://doi.org/10.1134/s1070363214020364
Evidence for Multidrug Resistance-1 P-Glycoprotein-dependent Regulation of Cellular ATP Permeability
Autor:
Noureddine Lomri, E. Mechetner, Gavin M. Braunstein, Richard M. Roman, Amy K. Davison, L. A. Simeoni, Erik M. Schwiebert, Andrew P. Feranchak, J. G. Fitz
Publikováno v:
Journal of Membrane Biology. 183:165-173
The mechanisms responsible for regulating epithelial ATP permeability and purinergic signaling are not well defined. Based on the observations that members of the ATP-binding cassette (ABC)1 family of proteins may contribute to ATP release, the purpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bb14241284444376b663987d7353f4b
https://doi.org/10.1007/s00232-001-0064-7
https://doi.org/10.1007/s00232-001-0064-7
Autor:
Holzmayer Tatyana, Edward A. Levine, R Mera, T. K. Das Gupta, C Bolliger, E Mechetner, S Bacus, Igor B. Roninson
Publikováno v:
Scopus-Elsevier
PURPOSE In addition to tumor size, grade, location, and the presence of metastases, other factors may be useful in prognostication for adults with soft tissue sarcoma (STS). This study examines the relationship of MDR-1 mRNA, p-glycoprotein (P-gp), K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e42c17a36e12d1771b75f02245ec094
https://doi.org/10.1200/jco.1997.15.10.3249
https://doi.org/10.1200/jco.1997.15.10.3249
Publikováno v:
European journal of biochemistry. 268(8)
Conformational changes accompanying P-glycoprotein (Pgp) mediated drug transport are reflected by changes in the avidity of certain monoclonal antibodies (mAbs). More of the UIC2 mAb binds to Pgp-expressing cells in the presence of substrates or modu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d518479800b7c4cdee909f5458d85173
https://pubmed.ncbi.nlm.nih.gov/11298761
https://pubmed.ncbi.nlm.nih.gov/11298761
Publikováno v:
Cancer detection and prevention. 24(5)
P-glycoprotein (P-gp) acts as an active efflux mechanism for a large number of cytostatics and seems to be involved in the frequent failure of cancer chemotherapy. The molecular events of substrate recognition and transport still are not understood c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ae0c370b23f85704a25dcfa0c71f76d5
https://pubmed.ncbi.nlm.nih.gov/11129983
https://pubmed.ncbi.nlm.nih.gov/11129983
Publikováno v:
Gynecologic Oncology. 107:377-378
2532 Background: To determine the biomarker expression and drug resistance patterns of undifferentiated ovarian cancers. Methods: Biomarker expression was determined by immunohistochemistry. In vitro drug resistance profiles were analyzed by assays e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247a5ee050f2713ac8ac25168d0c8ef8
https://doi.org/10.1016/j.ygyno.2007.08.048
https://doi.org/10.1016/j.ygyno.2007.08.048
Autor:
Z, Rahman, J, Kavanagh, R, Champlin, R, Giles, E, Hanania, S, Fu, Z, Zu, R, Mehra, F, Holmes, A, Kudelka, D, Claxton, C, Verschraegen, J, Gajewski, M, Andreeff, S, Heimfeld, R, Berenson, D, Ellerson, L, Calvert, E, Mechetner, T, Holzmayer, A, Dayne, J, Hamer, C, Bachier, J, Ostrove, A, Deisseroth
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(11)
Most patients relapse after high-dose chemotherapy (HDCT) with autologous stem-cell transplantation (ASCT) for metastatic breast cancer. Further chemotherapy immediately after hematopoietic recovery from ASCT is not given for fear of irreversibly dam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d63d6cc2145b45072741ea54b1bbbab5
https://pubmed.ncbi.nlm.nih.gov/9829734
https://pubmed.ncbi.nlm.nih.gov/9829734
Publikováno v:
Blood. 88(6)
The cell-surface expression and the functional status of the CD95/Fas antigen on primitive hematopoietic progenitors (PHPs) freshly isolated from human fetal liver (FL) were studied. PHPs were phenotypically defined as CD34++ CD38 -/+ cells. The most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69110b8b98f8b449ea0cf4c9f457d2b4
https://pubmed.ncbi.nlm.nih.gov/8822920
https://pubmed.ncbi.nlm.nih.gov/8822920
Autor:
L. Peterson, J. Ma, Marilyn K. Davis, Ossama Tawfik, Julia Chapman, E. Mechetner, R. Parker, Qamar J. Khan
Publikováno v:
Journal of Clinical Oncology. 25:16055-16055
16055 Background: The reliability of molecular biomarkers as predictors of treatment outcome remains unclear and, in relation to drug resistance even less is known. Immunohistochemical (IHC) expression of biomarkers and in vitro drug resistance (IVDR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4524a9895ee90f698c48191526b2dfd0
https://doi.org/10.1200/jco.2007.25.18_suppl.16055
https://doi.org/10.1200/jco.2007.25.18_suppl.16055
Autor:
M. Patel, Sandeep Singh Grewal, E. Mechetner, R. Sehgal, C. Yee, B. Yestrepsky, R. Parker, Supriya K. Saha, Kimberly Barber, David Wiese
Publikováno v:
Journal of Clinical Oncology. 25:14509-14509
14509 Background: Lymph Node (LN) status is the most important prognostic factor in colon cancer (Cca). Angiogenesis Index (AI) has been studied as a prognostic marker in various solid tumors with conflicting results. Hence, a retrospective analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0151e396c36352692241e1ab3726a799
https://doi.org/10.1200/jco.2007.25.18_suppl.14509
https://doi.org/10.1200/jco.2007.25.18_suppl.14509