Zobrazeno 1 - 10 of 443 pro vyhledávání: '"E McKnight"'
1
Akademický článek
The feasibility and impact of implementing a computer-guided consultation to target health inequality in Asthma
Autor: B. Chakrabarti, B. Kane, C. Barrow, J. Stonebanks, L. Reed, M. G. Pearson, L. Davies, M. Osborne, P. England, D. Litchfield, E. McKnight, R. M. Angus
Publikováno v: npj Primary Care Respiratory Medicine, Vol 33, Iss 1, Pp 1-7 (2023)
Abstract Greater Manchester has a greater prevalence and worse asthma outcomes than the national average. This study aims to evaluate a digital approach to primary care asthma management and in particular the initial impact of implementing Clinical D
Externí odkaz: https://doaj.org/article/83116c04f19e4f528450b4ce480cd1e5
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2
Akademický článek
Tup1 is critical for transcriptional repression in Quiescence in S. cerevisiae.
Autor: Thomas B Bailey, Phaedra A Whitty, Eric U Selker, Jeffrey N McKnight, Laura E McKnight
Publikováno v: PLoS Genetics, Vol 18, Iss 12, p e1010559 (2022)
Upon glucose starvation, S. cerevisiae shows a dramatic alteration in transcription, resulting in wide-scale repression of most genes and activation of some others. This coincides with an arrest of cellular proliferation. A subset of such cells enter
Externí odkaz: https://doaj.org/article/72794eba61354e779721f234b88cc24d
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3
Elektronická kniha
Pirate Alley : Commanding Task Force 151 Off Somalia
Autor: Terence E McKnight, Michael Hirsch
Named a'Notable Naval Book of 2012'by Proceedings magazine, Pirate Alley is now available in paperback. The book provides an in-depth look at every aspect of Somali piracy, from how the pirates operate to how the actions of a relative handful of yout
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5
Akademický článek
Rapid and inexpensive preparation of genome-wide nucleosome footprints from model and non-model organisms
Autor: Laura E. McKnight, Johnathan G. Crandall, Thomas B. Bailey, Orion G.B. Banks, Kona N. Orlandi, Vi N. Truong, Drake A. Donovan, Grace L. Waddell, Elizabeth T. Wiles, Scott D. Hansen, Eric U. Selker, Jeffrey N. McKnight
Publikováno v: STAR Protocols, Vol 2, Iss 2, Pp 100486- (2021)
Summary: MNase-seq (micrococcal nuclease sequencing) is used to map nucleosome positions in eukaryotic genomes to study the relationship between chromatin structure and DNA-dependent processes. Current protocols require at least two days to isolate n
Externí odkaz: https://doaj.org/article/d409f5f1fb93445094f34ee12464b1ee
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6
Akademický článek
Basis of specificity for a conserved and promiscuous chromatin remodeling protein
Autor: Drake A Donovan, Johnathan G Crandall, Vi N Truong, Abigail L Vaaler, Thomas B Bailey, Devin Dinwiddie, Orion GB Banks, Laura E McKnight, Jeffrey N McKnight
Publikováno v: eLife, Vol 10 (2021)
Eukaryotic genomes are organized dynamically through the repositioning of nucleosomes. Isw2 is an enzyme that has been previously defined as a genome-wide, nonspecific nucleosome spacing factor. Here, we show that Isw2 instead acts as an obligately t
Externí odkaz: https://doaj.org/article/7599b447105d410f840289c833829d47
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8
Akademický článek
Engineered Chromatin Remodeling Proteins for Precise Nucleosome Positioning
Autor: Drake A. Donovan, Johnathan G. Crandall, Orion G.B. Banks, Zena D. Jensvold, Vi Truong, Devin Dinwiddie, Laura E. McKnight, Jeffrey N. McKnight
Publikováno v: Cell Reports, Vol 29, Iss 8, Pp 2520-2535.e4 (2019)
Summary: Regulation of chromatin structure is essential for controlling access of DNA to factors that require association with specific DNA sequences. Here we describe the development and validation of engineered chromatin remodeling proteins (E-ChRP
Externí odkaz: https://doaj.org/article/3984e15388df4808b76bff7c482bb485
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