Zobrazeno 1 - 10
of 77
pro vyhledávání: '"E McInerney"'
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 7, Pp 2982-3000 (2022)
Adult brain tumors (glioma) represent a cancer of unmet need where standard-of-care is non-curative; thus, new therapies are urgently needed. It is unclear whether isocitrate dehydrogenases (IDH1/2) when not mutated have any role in gliomagenesis or
Externí odkaz:
https://doaj.org/article/2794f1d317b5410bbd896c42586ecb0d
Autor:
James P. Beirne, Alan Gilmore, Caitríona E. McInerney, Aideen Roddy, W. Glenn McCluggage, Ian J.G. Harley, M. Abdullah Alvi, Kevin M. Prise, Darragh G. McArt, Paul B. Mullan
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 3359-3371 (2022)
Introduction: Cancers presenting at advanced stages inherently have poor prognosis. High grade serous carcinoma (HGSC) is the most common and aggressive form of tubo-ovarian cancer. Clinical tests to accurately diagnose and monitor this condition are
Externí odkaz:
https://doaj.org/article/1c8bf9d25c064531ac26941f78c36845
Autor:
Alice R. Owens, Caitríona E. McInerney, Kevin M. Prise, Darragh G. McArt, Anna Jurek-Loughrey
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-22 (2021)
Abstract Background Liver cancer (Hepatocellular carcinoma; HCC) prevalence is increasing and with poor clinical outcome expected it means greater understanding of HCC aetiology is urgently required. This study explored a deep learning solution to de
Externí odkaz:
https://doaj.org/article/4ecee810662d4de480abda7b6aa9c228
Autor:
Aideen C. Roddy, Caitríona E. McInerney, Tom Flannery, Estelle G. Healy, James P. Stewart, Veronica J. Spence, Jamie Walsh, Manuel Salto-Tellez, Darragh G. McArt, Kevin M. Prise
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1219 (2023)
Glioblastoma (GBM) is the most prevalent and aggressive adult brain tumor. Despite multi-modal therapies, GBM recurs, and patients have poor survival (~14 months). Resistance to therapy may originate from a subpopulation of tumor cells identified as
Externí odkaz:
https://doaj.org/article/f0c8e8ffdc1141a29cf7ee38fcb6596a
Autor:
Butterworth, Bríanna N. Kerr, Daniel Duffy, Caitríona E. McInerney, Ashton Hutchinson, Inaya Dabaja, Rana Bazzi, Stéphane Roux, Kevin M. Prise, Karl T.
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 10032
Glioblastoma (GBM) is known as the most aggressive type of malignant brain tumour, with an extremely poor prognosis of approximately 12 months following standard-of-care treatment with surgical resection, radiotherapy (RT), and temozolomide treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::b203c401b6cc280b0b9817464934e67f
Publikováno v:
American Journal of Medical Genetics Part A. 188:1435-1442
Patient-reported concerns indicate that gastrointestinal (GI) manifestations affect the skeletal dysplasia population, but quantitative information regarding prevalence and severity of GI issues is limited. We examined the frequency and characteristi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48276383939f5c38a65bb557525abce7
https://doi.org/10.1002/ajmg.a.62658
https://doi.org/10.1002/ajmg.a.62658
Publikováno v:
Journal of the American Medical Directors Association. 24:773-781.e5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::224adfb3efabcd3322938d5d290ea3ba
https://doi.org/10.1016/j.jamda.2023.03.003
https://doi.org/10.1016/j.jamda.2023.03.003
Autor:
Kelly L. Gorres, Derek Daigle, Sudharshan Mohanram, Grace E. McInerney, Danielle E. Lyons, George Miller
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT Reactivation of Epstein-Barr virus (EBV) from latency into the lytic phase of its life cycle allows the virus to spread among cells and between hosts. Valproic acid (VPA) inhibits initiation of the lytic cycle in EBV-infected B lymphoma cell
Externí odkaz:
https://doaj.org/article/cf69ace380fa4a8f868716425cabda6e
Autor:
Caitríona E. McInerney, Kevin M. Prise, Anna Jurek-Loughrey, Darragh G. McArt, Alice R. Owens
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-22 (2021)
Owens, A R, McInerney, C E, Prise, K M, McArt, D G & Jurek-Loughrey, A 2021, ' Novel deep learning-based solution for identification of prognostic subgroups in liver cancer (Hepatocellular carcinoma) ', BMC Bioinformatics, vol. 22, 563 . https://doi.org/10.1186/s12859-021-04454-4
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-22 (2021)
Owens, A R, McInerney, C E, Prise, K M, McArt, D G & Jurek-Loughrey, A 2021, ' Novel deep learning-based solution for identification of prognostic subgroups in liver cancer (Hepatocellular carcinoma) ', BMC Bioinformatics, vol. 22, 563 . https://doi.org/10.1186/s12859-021-04454-4
Background Liver cancer (Hepatocellular carcinoma; HCC) prevalence is increasing and with poor clinical outcome expected it means greater understanding of HCC aetiology is urgently required. This study explored a deep learning solution to detect biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a15b28f6f6cd73b384be4d7cba5f5e
https://doi.org/10.1186/s12859-021-04454-4
https://doi.org/10.1186/s12859-021-04454-4
Autor:
Kevin M. Prise, Kienan Savage, Caitríona E. McInerney, Manuel Salto-Tellez, Frank Emmert-Streib, Darragh G. McArt, Alexey Stupnikov, Stuart McIntosh, Richard D Kennedy
Publikováno v:
Stupnikov, A, McInerney, C E, Savage, K I, McIntosh, S A, Emmert-Streib, F, Kennedy, R, Salto-Tellez, M, Prise, K M & McArt, D G 2021, ' Robustness of differential gene expression analysis of RNA-seq ', Computational and Structural Biotechnology Journal, vol. 19, pp. 3470-3481 . https://doi.org/10.1016/j.csbj.2021.05.040
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 3470-3481 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 3470-3481 (2021)
Graphical abstract
RNA-sequencing (RNA-seq) is a relatively new technology that lacks standardisation. RNA-seq can be used for Differential Gene Expression (DGE) analysis, however, no consensus exists as to which methodology ensures robust and r
RNA-sequencing (RNA-seq) is a relatively new technology that lacks standardisation. RNA-seq can be used for Differential Gene Expression (DGE) analysis, however, no consensus exists as to which methodology ensures robust and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa0eb57b0d81cfada53bb28bee42d5f
https://pure.qub.ac.uk/en/publications/e1e789db-0e5a-4081-ba4e-64282dfe53d0
https://pure.qub.ac.uk/en/publications/e1e789db-0e5a-4081-ba4e-64282dfe53d0
