Zobrazeno 1 - 10
of 19
pro vyhledávání: '"E Marcel, Van Gelderen"'
Publikováno v:
Journal of Electrocardiology. 47:856-862
Background Detection of food-induced QTc shortening has been proposed as an assay sensitivity in thorough QT/QTc (TQT) studies. Data of a large clinical study were used to investigate the food effects on QTc intervals. Methods Day-time drug-free 12-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd15fdc8dc3ff03b9bf457eb8e193377
https://doi.org/10.1016/j.jelectrocard.2014.07.026
https://doi.org/10.1016/j.jelectrocard.2014.07.026
Publikováno v:
Journal of Cardiovascular Electrophysiology. 25:1232-1241
E14-Compatible Holter Bin and QTcI Introduction The Holter bin method evaluates QT interval changes in the presence of heart rate changes without correcting the QT interval. However, the method does not allow time-matched comparisons, thus contradict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63420af19a76aafa9613e3bf5adf2baa
https://doi.org/10.1111/jce.12450
https://doi.org/10.1111/jce.12450
Autor:
Reiner Tretter, E. Marcel van Gelderen, John Meijer, Walter Krauwinkel, Gregory Strabach, Virginie Kerbusch
Publikováno v:
Clinical Pharmacology in Drug Development. 2:255-263
Mirabegron, a selective β3-adrenoceptor agonist, is approved for the treatment of overactive bladder (OAB). Solifenacin is a muscarinic receptor antagonist widely used in the treatment of OAB. This open-label, 1-sequence, 2-arm study investigated wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b54f125c0101eb41b076bbcc5bc3214c
https://doi.org/10.1002/cpdd.37
https://doi.org/10.1002/cpdd.37
Publikováno v:
Journal of Electrocardiology. 45:571-581
Objective A statistical modelling study investigated whether incorporating the curvatures of QT/RR patterns into the individual-specific QT heart rate correction increases QTc data accuracy. Methods Repeated ECG readings were available from 4 differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af198f65231373ce578aee761fc63f46
https://doi.org/10.1016/j.jelectrocard.2012.07.017
https://doi.org/10.1016/j.jelectrocard.2012.07.017
Publikováno v:
Journal of electrocardiology. 48(2)
Detection of QTc decreases after meal intake was proposed as a possible proof of assay sensitivity in studies of drug-induced QTc changes. However, day-to-day reproducibility of QTc decreases after meal intake has not been established.Holter recordin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09e75bc440b7d5acb754fb60cd1b5b9
https://pubmed.ncbi.nlm.nih.gov/25601409
https://pubmed.ncbi.nlm.nih.gov/25601409
Publikováno v:
Journal of cardiovascular electrophysiology. 25(11)
The Holter bin method evaluates QT interval changes in the presence of heart rate changes without correcting the QT interval. However, the method does not allow time-matched comparisons, thus contradicting available guidance and good practice. We rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::694ad36ffd1d4ee31c3b861acf3c1342
https://pubmed.ncbi.nlm.nih.gov/24801246
https://pubmed.ncbi.nlm.nih.gov/24801246
Publikováno v:
Journal of Electrocardiology. 48:276-277
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c47cc5a57285be4f3e822ce1034a2aec
https://doi.org/10.1016/j.jelectrocard.2015.01.005
https://doi.org/10.1016/j.jelectrocard.2015.01.005
Publikováno v:
Journal of electrocardiology. 47(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2018723935f49d9e94c571668f596d
https://pubmed.ncbi.nlm.nih.gov/24468293
https://pubmed.ncbi.nlm.nih.gov/24468293
Publikováno v:
Journal of electrocardiology. 46(6)
The study investigated whether the beat-to-beat QT interval variability relationship to the mean heart rate and the RR interval variability depended on the cardiovascular autonomic status changed by postural positioning. Repeated long-term 12-lead Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b6e81ff5a6d1bc5e241d06ede68da5
https://pubmed.ncbi.nlm.nih.gov/23938108
https://pubmed.ncbi.nlm.nih.gov/23938108
Publikováno v:
European Journal of Pharmacology. 284:51-60
The sensory neuropeptide, calcitonin gene-related peptide (alpha-CGRP), has been implicated in the pathogenesis of migraine headache. The present study aimed to evaluate the effects of intracarotid infusions of human alpha-CGRP (10, 30 and 100 pmol/k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5bd4b306abb15b63f9eab65c5d8746
https://doi.org/10.1016/0014-2999(95)00366-s
https://doi.org/10.1016/0014-2999(95)00366-s