Effects of meal composition and meal timing on the expression of genes involved in hepatic drug metabolism in rats.

Autor: E M de Vries, J E Oosterman, H M Eggink, P de Goede, S Sen, E Foppen, O Boudzovitch-Surovtseva, A Boelen, J A Romijn, S E laFleur, A Kalsbeek

Publikováno v: PLoS ONE, Vol 12, Iss 10, p e0185520 (2017)

With chronotherapy, drug administration is synchronized with daily rhythms in drug clearance and pharmacokinetics. Daily rhythms in gene expression are centrally mastered by the suprachiasmatic nucleus of the hypothalamus as well as by tissue clocks

Externí odkaz: https://doaj.org/article/29e290a5fbd8404787f2f192a9e505ba

Unmasking a silent killer: Prevalence of diagnosed and undiagnosed diabetes mellitus among people living with HIV in rural South Africa

Autor: Annemiek E. M. de Vries, Zanele Xaba, Sehulong R. Moraba, Luise Goerlitz, Hugo A. Tempelman, Kerstin Klipstein‐Grobusch, Lucas E. Hermans, Karine Scheuermaier, Walter L. J. M. Devillé, Alinda G. Vos

Publikováno v: Tropical Medicine & International Health. 28:367-373

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f042f9caf8715eafe8689389a73df84
https://doi.org/10.1111/tmi.13871

A Novel Role for the Thyroid Hormone-Activating Enzyme Type 2 Deiodinase in the Inflammatory Response of Macrophages

Autor: Ellen A. Fliers, Olga V. Surovtseva, Anita Boelen, J. Stap, E. M. de Vries, Joan Kwakkel

Publikováno v: Endocrinology, 155(7), 2725-2734. The Endocrine Society

Deiodinase type 2 (D2) is a thyroid hormone-activating enzyme converting the prohormone T-4 into the active hormone T-3. In the present study, we show for the first time that D2 is up-regulated in the mouse liver during acute and chronic inflammation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3e8a9591abed4f781df60806db8f00
https://doi.org/10.1210/en.2013-2066

The Role of Hypothalamic NF-κB Signaling in the Response of the HPT-Axis to Acute Inflammation in Female Mice

Autor: Heike Heuer, F. W. Pfrieger, Sigrun Nagel, S. M. Sundaram, Ronny Haenold, Anita Boelen, E. M. de Vries, Ellen A. Fliers

Publikováno v: Endocrinology
Endocrinology, Oxford University Press, 2016, 157 (7), pp.2947-2956. ⟨10.1210/en.2016-1027⟩
Endocrinology, 157(7), 2947-2956. The Endocrine Society

A large proportion of critically ill patients have alterations in the hypothalamus-pituitary-thyroid (HPT) axis, collectively known as the nonthyroidal illness syndrome. Nonthyroidal illness syndrome is characterized by low serum thyroid hormone (TH)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd48b8709a1e8224ab1fc2af3f8c930a
https://hal.archives-ouvertes.fr/hal-02882613

Fasting-induced changes in hepatic thyroid hormone metabolism in male rats are independent of autonomic nervous input to the liver

Autor: Leslie Eggels, Ellen A. Fliers, Mariëtte T. Ackermans, Anita Boelen, H C van Beeren, E. M. de Vries, Andries Kalsbeek

Publikováno v: Endocrinology, 155(12), 5033-5041. The Endocrine Society
Endocrinology. The Endocrine Society

During fasting, profound changes in the regulation of the hypothalamus-pituitary-thyroid axis occur in order to save energy and limit catabolism. In this setting, serum T3 and T4 are decreased without an appropriate TSH and TRH response reflecting ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee975f6047f9cb7bc5dc0c5fdd3ae21
https://pure.amc.nl/en/publications/fastinginduced-changes-in-hepatic-thyroid-hormone-metabolism-in-male-rats-are-independent-of-autonomic-nervous-input-to-the-liver(55c25b3c-a464-4cff-b181-3affb430412c).html