Zobrazeno 1 - 10
of 110
pro vyhledávání: '"E M Wintour"'
Publikováno v:
Placenta. 29:840-847
Aquaporins were first described as channels which increased permeability of lipid membranes to water, in response to osmotic and/or hydrostatic gradients. Some were shown to increase permeability also of other small solutes, particularly urea and gly
Autor:
Miodrag Dodic, E. M. Wintour, Karen M. Moritz, M. J. De Blasio, Julie A. Owens, Andrew J. Jefferies
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 293:E75-E82
An adverse intrauterine environment increases the risk of developing various adult-onset diseases, whose nature varies with the timing of exposure. Maternal undernutrition in humans can increase adiposity, and the risk of coronary heart disease and i
Autor:
Miodrag Dodic, Clive N. May, Megan L Cock, A. T. McAlinden, Andrew J. Jefferies, Roger G. Evans, Karen M. Moritz, E. M. Wintour
Publikováno v:
The Journal of Physiology. 571:651-660
Prenatal exposure to elevated maternal glucocorticoids (dexamethasone (DEX) or cortisol (CORT)) for 2 days early in pregnancy can 'programme' alterations in adult offspring of sheep, including elevated arterial pressure. DEX treatment also results in
Autor:
Arunmozhiarasi Armugam, T. Ferraro, Stuart B. Hooper, E. M. Wintour, H. Liu, Irene Koukoulas, Kandiah Jeyaseelan, N. Dawson, A. Thiel
Publikováno v:
The Journal of Physiology. 551:503-514
Fetal lung development is dependent upon secretion of liquid into the future airways which must be cleared at birth to establish air-breathing. Aquaporins (AQP) 1, 3, 4 and 5 are membranous water channel proteins that are present in the lung after bi
Publikováno v:
Endocrinology. 143:4455-4463
Ovine fetuses exposed to high concentrations of synthetic (dexamethasone, D) or naturally occurring glucocorticoids (cortisol, F) in utero during early gestation develop high blood pressure in adulthood. To investigate potential mechanisms involved,
Autor:
Irene Koukoulas, E. M. Wintour, Kandiah Jeyaseelan, T. Ferraro, H. Johnston, N. Dawson, L. Earnest, R Baird, Arunmozhiarasi Armugam
Publikováno v:
Placenta. 21:88-99
A sensitive and highly reproducible method has been used to show that Aquaporin 3 (AQP 3 ) mRNA is present in the ovine placenta and chorion from at least 60 days of gestation (term=145–150d) with levels increasing substantially (>16 fold) at 100 d
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 26:857-864
1. The role of the kidneys in the maintenance of normal foetal plasma (FP) composition and hormone concentrations was examined in the present study. Five ovine foetuses were chronically cannulated and nephrectomized (nephx) at 100 +/- 1 days of gesta
Publikováno v:
Molecular and Cellular Endocrinology. 157:161-170
The expression and regulation of the receptors for angiotensin II (both AT1 and AT2) were examined in the ovine fetal adrenal gland by RNase protection assay (RPA), in situ hybridisation histochemistry, immunohistochemistry and Western blotting. Both
Autor:
Clive N. May, E. M. Wintour, John P. Coghlan, Ze-Yan Yu, Miodrag Dodic, Eugenie R. Lumbers, Arianne Peers
Publikováno v:
Clinical Science. 97:103-109
Numerous epidemiological studies, together with mounting evidence from studies in animals, point to a correlation between an adverse intrauterine environment and the early onset of cardiovascular and metabolic diseases later in life. We were the firs
Autor:
E. M. Wintour, Karen M. Moritz
Publikováno v:
ResearcherID
This review highlights the important roles the mesonephros may play in development. In the ovine fetus it is an excretory and endocrine organ and may contribute to the formation of normal gonads and adrenals. The metanephros of the ovine fetus has th