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Toxic interactions of the munitions compounds TNT and RDX in F344 rats*1, *2

Autor: D. E. Gordon, E M Furedi, J.J. Barkley, P. M. Lish, B. S. Levine

Publikováno v: Fundamental and Applied Toxicology. 15:373-380

The potential toxic interactions in F344 rats of the munitions compounds trinitrotoluene (TNT) and hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) were examined following their coadministration in the diet. Groups of 10 rats per sex received TNT at dos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::23cea6f61047517a70b2dd2b18bfc7c1
https://doi.org/10.1016/0272-0590(90)90062-o

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Toxic Interactions of the Munitions Compounds TNT and RDX in F344 Rats

Autor: B. S. LEVINE, E. M. FUREDI, D. E. GORDON, J. J. BARKLEY, P. M. LISH

Publikováno v: Toxicological Sciences. 15:373-380

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb743619ee4ce2c207c47049249d759e
https://doi.org/10.1093/toxsci/15.2.373

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Phenolphthalein induces thymic lymphomas accompanied by loss of the p53 wild type allele in heterozygous p53-deficient (+/-) mice

Autor: John E. French, E M Furedi-Machacek, John C. Seely, Julie F. Foley, Ronald A. Herbert, Stanley Stasiewicz, June K. Dunnick, Jerry F. Hardisty, Gregory D. Lacks

Publikováno v: Toxicologic pathology. 25(6)

Epidemiology studies have indicated that many human cancers are influenced by environmental factors. Genetically altered mouse model systems offer us the opportunity to study the interaction of chemicals with genetic predisposition to cancer. Using t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8375c533057f35c9356394764460dc29
https://pubmed.ncbi.nlm.nih.gov/9437796

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Toxic interactions of the munitions compounds TNT and RDX in F344 rats

Autor: B S, Levine, E M, Furedi, D E, Gordon, J J, Barkley, P M, Lish

Publikováno v: Fundamental and applied toxicology : official journal of the Society of Toxicology. 15(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::383a510cdc183d3c50647e0949995884
https://pubmed.ncbi.nlm.nih.gov/2227162

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Six month oral toxicity study of trinitrotoluene in beagle dogs

Autor: J.H. Rust, J.J. Barkley, E M Furedi, B.S. Levine, Paul M Lish

Publikováno v: Toxicology. 63(2)

This study was conducted to evaluate the toxicity of the munitions compound 2,4,6-trinitrotoluene (TNT; CAS Reg. No. 118-96-7) in beagle dogs when administered daily for 26 weeks by capsule. Groups of six dogs per sex received TNT at doses of 0 (vehi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a51143d8240d56d926058fb3d70b452
https://pubmed.ncbi.nlm.nih.gov/2399537

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Subchronic toxicity of trinitrotoluene in Fischer 344 rats

Autor: J.J. Barkley, Paul M Lish, D. E. Gordon, E M Furedi, Barry S Levine

Publikováno v: Toxicology. 32(3)

This study was conducted to evaluate the toxicity of trinitrotoluene (TNT) in Fischer 344 rats when administered in the diet for 13 weeks. Groups of 10 rats per sex received TNT at doses of 1, 5, 25, 125 or 300 mg/kg/day. Thirty rats per sex served a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3c9ca44a454198754994900946b491
https://pubmed.ncbi.nlm.nih.gov/6474486

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