Výsledky vyhledávání - "E M Dorokhova"

A comparative analysis of the distribution of glyprolines after their administration by different ways

Autor: N. F. Myasoedov, V. K. Meshavkin, Yu. A. Zolotarev, E. M. Dorokhova, L. A. Andreeva, G. E. Samonina, L. Yu. Alfeeva, T. S. Pavlov, V. S. Kozik, K. E. Baglikova, I. P. Ashmarin, G. N. Kopylova, B. V. Vaskovsky, S. E. Edeeva, N. V. Kost, A. A. Zozulya, A. K. Dadayan, O. Yu. Sokolov

Publikováno v: Russian Journal of Bioorganic Chemistry. 34:415-420

The distribution of the glyprolines, Pro-Gly-Pro and Thr-Lys-Pro-Arg-Pro-Gly-Pro (Selanc), was analyzed and compared in tissues of rat organs after different ways of their administration using the peptides uniformly labeled with tritium. Comparative

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::16df7564a43d43fdbd8f50f87b402847
https://doi.org/10.1134/s1068162008040043

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Degradation of the ACTH(4-10) analog Semax in the presence of rat basal forebrain cell cultures and plasma membranes

Autor: E. M. Dorokhova, L. Yu. Alfeeva, L. A. Andreeva, Igor A. Grivennikov, L. S. Inozemtseva, Yu. A. Zolotarev, A. K. Dadayan, N. F. Myasoedov, O. V. Dolotov

Publikováno v: Amino Acids. 30:403-408

Here a new approach of the elucidation of paths of proteolytic biodegradation of physiologically active peptides, based on the use of a peptide with isotopic label at all amino acid residues and the enrichment of HPLC samples with unlabeled peptide f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae258d11c175ad21a86173626284d011
https://doi.org/10.1007/s00726-006-0328-8

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Evenly tritium labeled peptides in study of peptide in vivo and in vitro biodegradation

Publikováno v: Russian Journal of Bioorganic Chemistry. 32:166-173

Biologically active peptides evenly labeled with tritium were used for studying the in vitro and in vivo biodegradation of the peptides. Tritium-labeled peptides with a specific radioactivity of 50–150 Ci/mmol were obtained by high temperature soli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::647024a96731f7cfab900bcced89192d
https://doi.org/10.1134/s1068162006020099

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The Binding of Semax, ACTH 4–10 Heptapeptide, to Plasma Membranes of the Rat Forebrain Basal Nuclei and Its Biodegradation

Autor: Iu A Zolotarev, E M Dorokhova, L. A. Andreeva, Igor A. Grivennikov, O. V. Dolotov, Miasoedov Nf, L Iu Alfeeva

Publikováno v: Russian Journal of Bioorganic Chemistry. 30:213-217

The binding characteristics of the peptide Semax (Met-Glu-His-Phe-Pro-Gly-Pro) to plasma membranes of basal nuclei of the rat forebrain and the dynamics of its degradation during its incubation with these membranes were studied. Binding of the homoge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d46e95d626ca233f451bb940b724ec
https://doi.org/10.1023/b:rubi.0000030127.46845.f0

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New development in the tritium labelling of peptides and proteins using solid catalytic isotopic exchange with spillover-tritium

Autor: Yu. A. Zolotarev, E. M. Dorokhova, A. K. Dadayan, B. V. Vaskovsky, Yu. A. Borisov, Eduard V. Bocharov, N. F. Myasoedov

Publikováno v: Amino Acids. 24:325-333

The mechanism of the reaction of high temperature solid state catalytic isotope exchange (HSCIE) of hydrogen in peptides with spillover-tritium at 140-180 degrees C was analyzed. This reaction was used for preparing [(3)H]enkephalins such as [(3)H]DA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::345149eec6ae13f68aab6d0a2b7bb122
https://doi.org/10.1007/s00726-002-0404-7

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Stereoselective effects in the solid-phase hydrogenation of unsaturatedl-hydroxyproline derivatives

Autor: Yu. A. Zolotarev, E. M. Dorokhova, E. V. Laskatelev, N. F. Myasoedov, Yu. A. Borisov, S. G. Rozenberg, V. S. Kozik

Publikováno v: Russian Chemical Bulletin. 46:1726-1729

The solid-phase catalytic hydrogenation of (R-4tert-butoxy-Δ1-pyrroline-2-carboxylic) acid under the action of hydrogen spillover was studied. The reaction proceeds stereoselectively with the predominant formation of thel-amino acid. The configurati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d532304e5190732e6ad0d7795fc12daa
https://doi.org/10.1007/bf02495124

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The solid-state catalytic synthesis of tritium labeled amino acids, peptides and proteins

Autor: N. F. Myasoedov, L. V. Neumivakin, E. M. Dorokhova, Yu. A. Zolotarev, Vladimir V. Zverlov, V. N. Nezavibatko, Yu. A. Borisov, Velikodvorskaia Ga, S. G. Rosenberg

Publikováno v: Amino Acids. 8:353-365

New catalytic reaction between a solid bioorganic compound and activated spillover tritium (ST), based on High-temperature Solid-state Catalytic Isotopic Exchange (HSCIE) was examined. The HSCIE mechanism and determination of the reactivity of hydrog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586ca77d0b00e4251c4863c969fb07e8
https://doi.org/10.1007/bf00806553

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High temperature solid state catalytic isotope exchange with deuterium and tritium

Autor: E. M. Dorokhova, D. A. Zaitsev, Yu. A. Zolotarev, V. S. Kozik, S. G. Rozenberg, N. F. Myasoedov

Publikováno v: Journal of Radioanalytical and Nuclear Chemistry Articles. 162:3-14

A method for synthesizing tritium- or deuterium-labeled amino acids, peptides and biogenic amines through high temperature solid state catalytic isotope exchange (HSCIE) is proposed. The dependence of the degree of isotope exchange in HSCIE on the st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::04e941e5fa96cdf7b35265aa44d0f786
https://doi.org/10.1007/bf02039919

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The synthesis of tritium-labelled alanine by solid-state catalytic reactions

Autor: N. F. Myasoedov, Zolotarev Yu. A., E. M. Dorokhova, S. G. Rosenberg, V. S. Kozik, V. Yu. Tatur

Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 31:71-75

The solid-state catalytic hydrogenation (SCH) of unsaturated precursor compound and the high-temperature solid-state catalytic isotope exchange (HSCIE) showed that the total incorporation of isotope and its distribution between the α-and β-position

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b43fb88d33b480857191ee77899000a
https://doi.org/10.1002/jlcr.2580310109

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[Solid phase reaction of hemoglobin with spillover hydrogen]

Autor: N. F. Myasoedov, Yu. A. Borisov, E. M. Dorokhova, A. K. Dadayan, V. S. Kozik, B. V. Vaskovsky, Yu. A. Zolotarev, R. Kh. Ziganshin

Publikováno v: Bioorganicheskaia khimiia. 35(1)

The reaction of high-temperature solid-state catalytic isotope exchange (HSCIE) between bovine hemoglobin and spillover hydrogen (SH) was studied. It was shown that, in the field of subunit contact, there is a significant decrease in ability for hydr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d569d8d522c23d093805b4863dacc04d
https://pubmed.ncbi.nlm.nih.gov/19377520

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