Zobrazeno 1 - 10
of 69
pro vyhledávání: '"E M, de Jong"'
Autor:
Adam M. Thorne, Justina C. Wolters, Bianca Lascaris, Silke B. Bodewes, Veerle A. Lantinga, Otto B. van Leeuwen, Iris E. M. de Jong, Kirill Ustyantsev, Eugene Berezikov, Ton Lisman, Folkert Kuipers, Robert J. Porte, Vincent E. de Meijer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Normothermic machine perfusion (NMP) after static cold storage is increasingly used for preservation and assessment of human donor livers prior to transplantation. Biliary viability assessment during NMP reduces the risk of post-transplant b
Externí odkaz:
https://doaj.org/article/4196b91cef814f6483a06b7a72696332
Autor:
Kapish Gupta, Jimmy P Xu, Tamir Diamond, Iris E M de Jong, Andrew Glass, Jessica Llewellyn, Neil D Theise, Orith Waisbourd-Zinman, Jeffrey D Winkler, Edward M Behrens, Clementina Mesaros, Rebecca G Wells
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301824 (2024)
Biliary atresia is a neonatal disease characterized by damage, inflammation, and fibrosis of the liver and bile ducts and by abnormal bile metabolism. It likely results from a prenatal environmental exposure that spares the mother and affects the fet
Externí odkaz:
https://doaj.org/article/74507efcbeca4a1daf62e83fff6e33fb
Autor:
Ditte Olsen, Niels Wellner, Mathias Kaas, Inge E. M. de Jong, Florence Sotty, Michael Didriksen, Simon Glerup, Anders Nykjaer
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Attention deficit hyperactivity disorder (ADHD) is the most frequently diagnosed neurodevelopmental disorder worldwide. Affected individuals present with hyperactivity, inattention, and cognitive deficits and display a characteristic paradox
Externí odkaz:
https://doaj.org/article/92593cd7cc714224b571f4954375bcbe
Autor:
Yvonne de Vries, MD, PhD, Isabel M. A. Brüggenwirth, BSc, Shanice A. Karangwa, MD, Fien A. von Meijenfeldt, BSc, Otto B. van Leeuwen, PhD, Laura C. Burlage, MD, PhD, Iris E. M. de Jong, MD, Annette S. H. Gouw, MD, PhD, Vincent E. de Meijer, MD, PhD, Ton Lisman, PhD, Robert J. Porte, MD, PhD
Publikováno v:
Transplantation Direct, Vol 7, Iss 9, p e741 (2021)
Background. Hypothermic oxygenated machine perfusion (HOPE) reduces ischemia-reperfusion injury of donor livers and is increasingly used in clinical transplantation. However, it remains unclear whether perfusion via the portal vein alone (HOPE) or vi
Externí odkaz:
https://doaj.org/article/7f0f666f4ffd4df4b0ba053029a14e60
Autor:
Iris E. M. de Jong, Michael E. Sutton, Marius C. van den Heuvel, Annette S. H. Gouw, Robert J. Porte
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
IntroductionChimerism after orthotopic liver transplantation (OLT) has largely been investigated in intrahepatic cellular constituents. However, little is known about chimerism in the extrahepatic and large intrahepatic bile ducts. Our aim was to eva
Externí odkaz:
https://doaj.org/article/5a69b211a25d49c782d81d7b574d9328
Publikováno v:
The Mesentery and Inflammation ISBN: 9783031177736
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97fede9e9f6141f4d8c0538ff4b7ef8f
https://doi.org/10.1007/978-3-031-17774-3_3
https://doi.org/10.1007/978-3-031-17774-3_3
Publikováno v:
Cells, Vol 9, Iss 4, p 982 (2020)
Necroptosis is a type of regulated cell death that is increasingly being recognized as a relevant pathway in different pathological conditions. Necroptosis can occur in response to multiple stimuli, is triggered by the activation of death receptors,
Externí odkaz:
https://doaj.org/article/95c9583003914d0e9071ac738cd59af0
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
The 5-HT6 receptor is a promising target for cognitive disorders, in particular for Alzheimer's disease (AD) and other CNS disorders. The high-affinity and selective 5-HT6 receptor antagonist idalopirdine (Lu AE58054) is currently in development for
Externí odkaz:
https://doaj.org/article/90099704715d4a1292189ee8ac76edd0
Publikováno v:
J Hepatol
Journal of Hepatology, 75(5), 1236-1238. ELSEVIER SCIENCE BV
Journal of Hepatology, 75(5), 1236-1238. ELSEVIER SCIENCE BV
[Image: see text]
Autor:
Ton Lisman, Eugenio Gaudio, Jasper van Praagh, S. Suriguga, Raditya Iswandana, Janneke Wiersema-Buist, Diletta Overi, Louise A van Wijk, Wouter T. van Haaften, Dorenda Oosterhuis, Iris E M de Jong, Robert J. Porte, Guido Carpino, Alix P M Matton, Peter Olinga, Annette S. H. Gouw
Publikováno v:
Hepatology, 69(4), 1719-1734. Wiley
Hepatology (Baltimore, Md.)
Hepatology (Baltimore, Md.)
Peribiliary glands (PBG) are a source of stem/progenitor cells organized in a cellular network encircling large bile ducts. Severe cholangiopathy with loss of luminal biliary epithelium has been proposed to activate PBG, resulting in cell proliferati