Zobrazeno 1 - 10
of 109
pro vyhledávání: '"E M, SHOOTER"'
Autor:
P J, Kahle, M, Jakowec, S J, Teipel, H, Hampel, G M, Petzinger, D A, Di Monte, G D, Silverberg, H J, Möller, J A, Yesavage, J R, Tinklenberg, E M, Shooter, G M, Murphy
Publikováno v:
Neurology. 54:1498-1504
Comparative study of CSF levels of tau and AD7C-neuronal thread protein (NTP) in patients with AD and control subjects.AD is characterized by neurofibrillary tangles composed of the abnormally hyperphosphorylated microtubule-associated protein tau. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ca591548ac55ff08ed1cff24d05368
https://doi.org/10.1212/wnl.54.7.1498
https://doi.org/10.1212/wnl.54.7.1498
Publikováno v:
Scopus-Elsevier
The role of the low affinity nerve growth factor receptor (p75(NGFR)) in NGF-mediated signaling is not yet understood. Here we show by co-immunoprecipitation that NGF activates a protein kinase that is directly associated with p75(NGFR) in dorsal roo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fcdc8fa07f94a640242d53d426603db
https://doi.org/10.1002/j.1460-2075.1996.tb00702.x
https://doi.org/10.1002/j.1460-2075.1996.tb00702.x
Autor:
A. A. Welcher, G. J. Snipes, J. R. Lupski, Sangeeta Pareek, R. A. Murphy, R. Schoener-Scott, Ueli Suter, E. M. Shooter, Pragna Patel
Publikováno v:
Journal of Biological Chemistry. 269:25795-25808
Mutations affecting the peripheral myelin protein-22 (PMP22) gene have been shown to be associated with inherited peripheral neuropathies. To provide the molecular basis for the analysis of such mutations, we have cloned and characterized the human P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c45521d47bbc970cc7179311ef39db2
https://doi.org/10.1016/s0021-9258(18)47318-8
https://doi.org/10.1016/s0021-9258(18)47318-8
Publikováno v:
Journal of Biological Chemistry. 268:10372-10379
Peripheral myelin protein, 22 kDa (PMP22), is a myelin molecule associated with Schwann cells in peripheral nerves (Snipes, G. J., Suter, U., Welcher, A. A., and Shooter, E. M. (1992) J. Cell Biol. 117, 225-238). Mutations affecting the PMP22 gene ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f10f888479466fc764c6e2b0e392d9ae
https://doi.org/10.1016/s0021-9258(18)82211-6
https://doi.org/10.1016/s0021-9258(18)82211-6
Publikováno v:
Journal of neuroscience research. 75(6)
Neurotrophins (NTs) play an important role in the modulation of synaptic transmission and in morphological changes in synaptic structures. Although there is agreement that brain-derived neurotrophic factor (BDNF) is sorted to large dense-core vesicle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4dab70468827954545bb6ffc49a82731
https://pubmed.ncbi.nlm.nih.gov/14994343
https://pubmed.ncbi.nlm.nih.gov/14994343
Autor:
J M, Cosgaya, E M, Shooter
Publikováno v:
Journal of neurochemistry. 79(2)
Nerve growth factor (NGF) regulates the activity of the transcription factor NF-kappaB (nuclear factor-kappaB) through its low affinity receptor, p75. In the present study we found that NGF binding to p75 induces nuclear translocation of p65 and incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d00cd5b14721de72ba8e8f143ab310b
https://pubmed.ncbi.nlm.nih.gov/11677267
https://pubmed.ncbi.nlm.nih.gov/11677267
Publikováno v:
Journal of neuroscience research. 62(2)
The short- and long-term effects of nerve growth factor (NGF) were studied on fibroblast cell lines stably expressing both TrkA and either wild-type p75 or a mutant that lacks the palmitoylation site of p75. The lack of palmitoylation had no effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e876b5a91d2d8e85bcfeab43a986f5fb
https://pubmed.ncbi.nlm.nih.gov/11020215
https://pubmed.ncbi.nlm.nih.gov/11020215
Publikováno v:
Glia. 25(4)
Peripheral myelin protein 22 (PMP22) was initially described as a minor component of peripheral myelin. Mutations affecting the PMP22 gene cause demyelinating neuropathies, supporting a role for the protein in PNS myelination. Furthermore, PMP22 carr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a68f5a6834d03f64a14c580ca70f9225
https://pubmed.ncbi.nlm.nih.gov/10028918
https://pubmed.ncbi.nlm.nih.gov/10028918
Autor:
J L, Twiss, H G, Wada, K S, Fok, S D, Chan, A N, Verity, G T, Baxter, E M, Shooter, H H, Sussman
Publikováno v:
Journal of neuroscience research. 51(4)
The role of the low affinity neurotrophin receptor p75LNTR in neurotrophin signal transduction remains open. Recent reports show that this receptor generates intracellular signals independent of Trk activity, and others imply that it collaborates wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d40bd2bbd2ee049daf5ef5438b4693d
https://pubmed.ncbi.nlm.nih.gov/9514198
https://pubmed.ncbi.nlm.nih.gov/9514198
Publikováno v:
Journal of neuroscience research. 51(4)
A growing body of evidence suggests that neurotrophins (NTs) play a critical role in synaptic plasticity and other activity dependent processes in the CNS. Release of these growth factors by neurons and neuroendocrine cells was recently shown to occu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0fa3af677c0e1919e21a88e60911b16
https://pubmed.ncbi.nlm.nih.gov/9514200
https://pubmed.ncbi.nlm.nih.gov/9514200