Zobrazeno 1 - 10
of 36
pro vyhledávání: '"E M, Oden"'
Autor:
E. M. Oden, George H. Miller, R. D'Souza, Menger Chung, Chin-Chung Lin, Samson Symchowicz, Hong-Ki Kim, J. Veals, C.A. Korduba, Eugene L. Moss, David Loebenberg, Josephine Lim
Publikováno v:
Journal of Antimicrobial Chemotherapy. 15:219-226
The pharmacokinetics of 14C-Sch 34343 were studied in rats and dogs following intravenous and intramuscular dosing. In both species, it was rapidly absorbed after intramuscular dosing. The serum AUC for total radioactivity and for intact drug after i
Publikováno v:
American Journal of Health-System Pharmacy. 38:1737-1742
The compatibility and stability of netilmicin sulfate in a concentration of 3 mg/ml in 37 intravenous injections and in 5% dextrose and 0.9% sodium chloride injection with 26 commonly used additives were studied. Compatibility between an intravenous
Publikováno v:
Antimicrobial Agents and Chemotherapy. 22:848-851
A high-pressure liquid chromatographic method was developed for quantitative determination in human serum of a new penem antibiotic known as Sch 29482 (5R,6S,8R-2-ethylthio-6(1-hydroxyethyl)penem-3-carboxylic acid). The method involves serum extracti
Publikováno v:
Journal of Antimicrobial Chemotherapy. 15:207-218
Sch 34343 showed a linear dose response (with respect to AUCs) in mice following both intravenous and subcutaneous administration. It was 100% bioavailable following subcutaneous administration. Peak serum levels, AUCs, beta-phase half-life and recov
Autor:
Roberta S. Hare, J. A. Waitz, George H. Miller, David Loebenberg, Menger Chung, Eugene L. Moss, E. M. Oden
Publikováno v:
Journal of Antimicrobial Chemotherapy. 9:221-231
Autor:
Samson Symchowicz, E. M. Oden, Menger Chung, Chin-Chung Lin, Richard Gural, George H. Miller, Elaine Radwanski, David Loebenberg
Publikováno v:
Journal of Antimicrobial Chemotherapy. 15:227-233
Pharmacokinetic parameters of Sch 34343 have been determined for mice, rats, rabbits, monkeys, dogs and humans and correlated among species as an exponential function of body weight. The pertinent pharmacokinetic parameters tested are apparent and st
Publikováno v:
Journal of Clinical Microbiology. 22:596-599
A sensitive immunoradiometric assay for recombinant alpha-2 interferon (IFN-alpha 2; SCH 30500) was developed by using the monoclonal antibody NK2. A polystyrene bead with polyclonal sheep anti-human IFN-alpha (Hu IFN-alpha) antibody adsorbed to it f
Autor:
A. Murawski, Raymond T. Testa, E. M. Oden, Marvin J. Weinstein, Gerald H. Wagman, Joseph A. Marquez, J. A. Waitz
Publikováno v:
The Journal of Antibiotics. 25:641-646
A new antibiotic, rosamicin, classified as a macrolide, has been isolated from the fermentation broth of a new species of Micromonospora, M. rosaria. The antibiotic is separated from the broth by a solvent extraction procedure and purified by column
Publikováno v:
The Journal of Antibiotics. 22:265-272
In vitro studies with megalomicin A base demonstrated enhanced activity with increased pH, decreased activity with increasing serum content in the medium and serum binding in the range of 20-30%. There is an inoculum effect with megalomicin A. In viv
Publikováno v:
Applied Microbiology. 16:624-627
A differential paper chromatographic assay for the components of the gentamicin complex, designated as C 1 , C 1a , and C 2 , is described. The gentamicins are separated on paper strips with the lower phase of a solvent mixture consisting of chlorofo