Zobrazeno 1 - 10
of 19
pro vyhledávání: '"E M, Gravallese"'
Autor:
D H, Solomon, J, Kay, J, Duryea, B, Lu, M B, Bolster, R A, Yood, R, Han, S, Ball, C, Coleman, E, Lo, A, Wohlfahrt, M, Sury, M, Yin, Z, Yu, A, Zak, E M, Gravallese
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 69(9)
Articular erosions correlate with disability in rheumatoid arthritis (RA). Biologic agents reduce erosion progression in RA, but erosion healing occurs infrequently. This study was undertaken to assess the effects of the anabolic agent teriparatide o
Autor:
N C, Walsh, K A, Alexander, C A, Manning, S, Karmakar, S K, Karmakar, J F, Wang, C M, Weyand, A R, Pettit, E M, Gravallese
Publikováno v:
Genes and immunity
Receptor activator of nuclear factor-kappaB-ligand (RANKL), encoded by the gene TNFSF11, is required for osteoclastogenesis, and its expression is upregulated in pathologic bone loss. Transcript variants of TNFSF11 messenger RNA (mRNA) have been desc
Publikováno v:
The Journal of Immunology. 147:2377-2383
The class II (Ia) MHC molecules are cell surface proteins that regulate the activation of T cells. B lymphocyte expression of class II molecules has been shown to be influenced by a number of external stimuli. It has been previously demonstrated that
Autor:
E J, Wexler, E M, Gravallese, P M, Czerniak, J J, Devenny, J, Longtine, M K, Wong, A M, Slee, J S, Kerr
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(8)
Tumor growth is dependent on the balance between cell proliferation and cell death, and these events occur heterogenously within an individual tumor. We present a methodology that provides integrative information about cell kinetics, cell death, and
Publikováno v:
Arthritis Research
The contribution of osteoclasts to the process of bone loss in inflammatory arthritis has recently been demonstrated. Studies in osteoclast biology have led to the identification of factors responsible for the differentiation and activation of osteoc
Publikováno v:
The Journal of rheumatology. 27(4)
It is not well appreciated that the clinical presentation of amyloid myopathy can mimic that of polymyositis. By retrospective clinicopathologic analysis we determined distinctive features of amyloid myopathy that differentiate the 2 diseases.Two pat
Publikováno v:
Arthritis and rheumatism. 43(2)
Osteoclast differentiation factor (ODF; also known as osteoprotegerin ligand, receptor activator of nuclear factor kappaB ligand, and tumor necrosis factor-related activation-induced cytokine) is a recently described cytokine known to be critical in
Autor:
S R, Goldring, E M, Gravallese
Publikováno v:
Arthritis Research
Rheumatoid arthritis represents an excellent model in which to gain insights into the local and systemic effects of joint inflammation on skeletal tissues. Three forms of bone disease have been described in rheumatoid arthritis. These include: focal
Publikováno v:
The American journal of pathology. 152(4)
Focal resorption of bone at the bone-pannus interface is common in rheumatoid arthritis (RA) and juvenile rheumatoid arthritis (JRA) and can result in significant morbidity. However, the specific cellular and hormonal mechanisms involved in this proc
Publikováno v:
The American journal of pathology. 150(4)
Pigmented villonodular synovitis (PVNS) and the histologically related lesion giant cell tumor of tendon sheath (GCTTS) are idiopathic, proliferative lesions that can induce osteolysis and formation of bone cysts. These lesions contain two predominan