Zobrazeno 1 - 10
of 94
pro vyhledávání: '"E M, Copeland"'
Autor:
James M. Seeger, Tomas D. Martin, R I Wesdorp, Lyle L. Moldawer, N J Espat, M B Welborn, Thomas S. Huber, Phillip J. Hess, H. S A Oldenburg, E M Copeland rd, J A Rauwerda
Publikováno v:
Critical Care Medicine. 28:3191-3197
Plasma proinflammatory, anti-inflammatory cytokine, and soluble tumor necrosis factor (TNF) receptor concentrations were examined in hospitalized patients after abdominal and thoracoabdominal aortic aneurysm (TAAA) repair, with and without left atria
Autor:
C C Solorzano, R Ksontini, J H Pruitt, P J Hess, P D Edwards, A Kaibara, A Abouhamze, T Auffenberg, R E Galardy, J N Vauthey, E M Copeland, C K Edwards, G Y Lauwers, M Clare-Salzler, S L MacKay, L L Moldawer, D D Lazarus
Publikováno v:
The Journal of Immunology. 158:414-419
TNF-alpha is a pleiotropic cytokine that exists both as a 26-kDa cell-associated and a 17-kDa soluble form. Recently, a class of matrix metalloproteinase inhibitors has been identified that can prevent the processing by TNF convertase of 26-kDa TNF-a
Publikováno v:
Annals of Surgical Oncology. 3:501-508
Little is known about amino acid transport in human neoplastic cells. We previously characterized L-arginine transport in the primary human colon cancer cell line, SW480, and found it is principally mediated by the sodium-independent system y+. In th
Autor:
Lyle L. Moldawer, Gregory S. Schultz, rd E M Copeland, L R Yaswen, Kirby I. Bland, Roy W. Tarnuzzer, Sally L. D. MacKay
Publikováno v:
Annals of Surgery. 221:767-777
OBJECTIVE: The authors determined the molecular mechanisms for the failure of transforming growth factor-beta (TGF-beta) to inhibit the growth of SW1116 and SW48 colon cancer cell lines. BACKGROUND: Transforming growth factor-beta is a bifunctional r
Publikováno v:
Annals of Surgical Oncology. 2:257-265
Epidermal growth factor (EGF) and transforming growth factor alpha (TGF alpha) are potent mitogens that contribute to abnormal growth regulation in colon cancer. Growth factors have been shown to regulate transmembrane nutrient uptake as an adaptive
Publikováno v:
Journal of Surgical Oncology. 58:77-82
The clinical syndrome of cachexia is characterized by anorexia, continued losses of lean body mass, and altered carbohydrate and lipid metabolism. As early as the 1930s, this "chronic wasting" syndrome had been identified as the most frequent immedia
Autor:
E. M. Copeland III
Publikováno v:
Annals of Surgical Oncology. 8:477-479
Publikováno v:
The American surgeon. 70(6)
The technique of identifying the sentinel lymph node (SLN) varies from each individual institution. Generally, the highest isotope count in a lymph node is considered the SLN, whereas other radioactive nodes might also be removed. The purpose of our
Autor:
C L, Tannahill, K, Fukuzuka, T, Marum, Z, Abouhamze, S L, MacKay, E M, Copeland, L L, Moldawer
Publikováno v:
Surgery. 126(2)
Tumor necrosis factor-alpha (TNF-alpha) is a member of a large family of predominantly homotrimeric type II membrane-associated proteins with both proinflammatory and apoptosis-inducing properties. Although TNF-alpha expression has been studied exten
Autor:
Lyle L. Moldawer, P G Woost, C C Solorzano, Sally L. D. MacKay, Troy Auffenberg, M Pettitjean, Gregory S. Schultz, S C Jones, E M Copeland rd, T G O'Daniel
Publikováno v:
Annals of surgical oncology. 4(8)
Transforming growth factor alpha (TGF-alpha) and its receptor (EGF-R) may regulate normal and malignant epithelial cell growth by an autocrine mechanism. We investigated the role of TGF-alpha in regulating head and neck SCC tumor growth.TGF-alpha and