Zobrazeno 1 - 9
of 9
pro vyhledávání: '"E M, Conner"'
Publikováno v:
Inflammatory bowel diseases. 2(2)
There is a growing body of both experimental and clinical evidence to suggest that chronic gut inflammation is associated with enhanced production of reactive metabolites of oxygen (e.g., superoxide, hydrogen peroxide) and nitrogen (e.g., nitric oxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::745493917695deefd75d28dab2fa4bad
https://pubmed.ncbi.nlm.nih.gov/23282521
https://pubmed.ncbi.nlm.nih.gov/23282521
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 296(1)
A specific and potent inhibitor of S-adenosyl-L-homocysteine (AdoHcy) hydrolase, 9-[(1'R,2'S,3'R)-2', 3'-dihydroxycyclopentanyl]adenine (DHCaA), was evaluated for its immunosuppressive efficacy on murine T-cell proliferation in vitro and in several a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c39c195a28342e3df76ce4d10f881256
https://pubmed.ncbi.nlm.nih.gov/11123369
https://pubmed.ncbi.nlm.nih.gov/11123369
Autor:
M B, Grisham, V J, Palombella, P J, Elliott, E M, Conner, S, Brand, H L, Wong, C, Pien, L M, Mazzola, A, Destree, L, Parent, J, Adams
Publikováno v:
Methods in enzymology. 300
It is becoming increasingly apparent that NF-kappa B plays a critical role in regulating the inflammatory response. Data obtained from studies in our laboratories demonstrate that the proteasome plays an important role in the inflammatory cascade by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ca660fef77bcfddf80467d8048d10722
https://pubmed.ncbi.nlm.nih.gov/9919536
https://pubmed.ncbi.nlm.nih.gov/9919536
Autor:
E M, Conner, S, Brand, J M, Davis, F S, Laroux, V J, Palombella, J W, Fuseler, D Y, Kang, R E, Wolf, M B, Grisham
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 282(3)
The objectives of this study were to (1) assess the role of the 26S proteasome complex in regulating the expression of the inducible isoform of nitric oxide synthase (iNOS) and vascular cell adhesion molecule-1 (VCAM-1) in a model of chronic granulom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f44e8f9a66b765d68c57706c731dbbc7
https://pubmed.ncbi.nlm.nih.gov/9316879
https://pubmed.ncbi.nlm.nih.gov/9316879
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 280(2)
The objective of this study was to quantitatively characterize the effects FK506 on the pathophysiology observed in a model of chronic granulomatous colitis in rats and compare these effects to those obtained with cyclosporin A (CyA). Chronic granulo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::370682357491603e665e047ca429239d
https://pubmed.ncbi.nlm.nih.gov/9023326
https://pubmed.ncbi.nlm.nih.gov/9023326
Publikováno v:
Inflammation. 21(1)
We have investigated the temporal relationship among proinflammatory cytokine expression, nitric oxide (NO) production and joint inflammation in the acute phase of bacterial cell wall-derived peptidoglycan polysaccharide (PG/PS)-induced arthritis. Ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e240d2fefee803c661175846939c595
https://pubmed.ncbi.nlm.nih.gov/9179627
https://pubmed.ncbi.nlm.nih.gov/9179627
Autor:
R J, Benschop, E C, Collins, R J, Darling, B W, Allan, D, Leung, E M, Conner, J, Nelson, B, Gaynor, J, Xu, X-F, Wang, R A, Lynch, B, Li, D, McCarty, E S, Nisenbaum, J L, Oskins, C, Lin, K W, Johnson, M G, Chambers
Publikováno v:
Osteoarthritis and Cartilage. (4):578-585
Summary Objective Investigate a role for calcitonin gene-related peptide (CGRP) in osteoarthritis (OA)-related pain. Design Neutralizing antibodies to CGRP were generated de novo . One of these antibodies, LY2951742, was characterized in vitro and te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3059a2606039e1ec40214ef7c794648c
Publikováno v:
Antimicrobial agents and chemotherapy. 31(8)
The therapeutic efficacy of zinc gluconate lozenge therapy in experimentally induced rhinovirus infection was assessed in two randomized controlled trials in susceptible adult volunteers. In trial 1, lozenges containing either zinc gluconate (23 mg o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad9ebb30ae4ea2ae9de50f4ded471e3
https://pubmed.ncbi.nlm.nih.gov/2820298
https://pubmed.ncbi.nlm.nih.gov/2820298
Publikováno v:
JAMA. 253(12)
Community-oriented primary care (COPC) is a variation on the primary care model, which is characterized by the complementary use of epidemiologic and primary care skills to systematically address the health care needs of a defined population. A study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8cb452bf8fc640f3f3d044ac918188f8
https://pubmed.ncbi.nlm.nih.gov/3974056
https://pubmed.ncbi.nlm.nih.gov/3974056