Zobrazeno 1 - 3
of 3
pro vyhledávání: '"E M, Bruin"'
Autor:
S. Pick, B. Freimark, E. M. Bruin, C. L. McAIlister, H. George, R. Goodman, L. R. Mantegna, R. L. Dowling, Janet S. Kerr, R. R. Harris, W. Feeser, M. Lischwe
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2, Iss 1, Pp 33-39 (1993)
Mediators of Inflammation, Vol 2, Iss 1, Pp 33-39 (1993)
The carrageenan pleurisy model, which is characterized by cellular influx and oedema, has been used to examine the effects of anti-inflammatory compounds such as naproxen. Interleukin-1alpha and beta (IL-1) are known to be pro-inflammatory mediators,
Autor:
S W, Wright, R R, Harris, J S, Kerr, A M, Green, D J, Pinto, E M, Bruin, R J, Collins, R L, Dorow, L R, Mantegna, S R, Sherk
Publikováno v:
Journal of Medicinal Chemistry. 35:4061-4068
Vinylogous hydroxamic acids (3-(N-hydroxy-N-alkylamino)-2-propen-1-ones, VHA) were prepared as antiinflammatory agents. The synthesis, chemical properties, and in vitro biological activities of these relatively unexplored compounds are described. The
Publikováno v:
Skin pharmacology : the official journal of the Skin Pharmacology Society. 3(1)
The possible utility of DuP 654, a potent 5-lipoxygenase inhibitor, for treating human inflammatory skin disease was investigated in murine skin treated with 1.0 mg arachidonic acid (AA). When DuP 654 was applied to murine skin treated with AA, it in