Výsledky vyhledávání

IL-1 and its role in rat carrageenan pleurisy

Autor: S. Pick, B. Freimark, E. M. Bruin, C. L. McAIlister, H. George, R. Goodman, L. R. Mantegna, R. L. Dowling, Janet S. Kerr, R. R. Harris, W. Feeser, M. Lischwe

Publikováno v: Mediators of Inflammation
Mediators of Inflammation, Vol 2, Iss 1, Pp 33-39 (1993)

The carrageenan pleurisy model, which is characterized by cellular influx and oedema, has been used to examine the effects of anti-inflammatory compounds such as naproxen. Interleukin-1alpha and beta (IL-1) are known to be pro-inflammatory mediators,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ed961487502a2959ba5bcbbc3d0a2a
http://europepmc.org/articles/PMC2365377

Zobrazit plný text záznamu

Synthesis, chemical, and biological properties of vinylogous hydroxamic acids: dual inhibitors of 5-lipoxygenase and IL-1 biosynthesis

Autor: S W, Wright, R R, Harris, J S, Kerr, A M, Green, D J, Pinto, E M, Bruin, R J, Collins, R L, Dorow, L R, Mantegna, S R, Sherk

Publikováno v: Journal of Medicinal Chemistry. 35:4061-4068

Vinylogous hydroxamic acids (3-(N-hydroxy-N-alkylamino)-2-propen-1-ones, VHA) were prepared as antiinflammatory agents. The synthesis, chemical properties, and in vitro biological activities of these relatively unexplored compounds are described. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1610f027838fd26641fc716db57f498d
https://doi.org/10.1021/jm00100a011

Zobrazit plný text záznamu

Cellular and biochemical characterization of the anti-inflammatory effects of DuP 654 in the arachidonic acid murine skin inflammation model

Autor: R R, Harris, W M, Mackin, D G, Batt, S M, Rakich, R J, Collins, E M, Bruin, N R, Ackerman

Publikováno v: Skin pharmacology : the official journal of the Skin Pharmacology Society. 3(1)

The possible utility of DuP 654, a potent 5-lipoxygenase inhibitor, for treating human inflammatory skin disease was investigated in murine skin treated with 1.0 mg arachidonic acid (AA). When DuP 654 was applied to murine skin treated with AA, it in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::146460f0c5b6f114fc77d6181db2a98f
https://pubmed.ncbi.nlm.nih.gov/2167696

Zobrazit plný text záznamu

Akademický článek

Azetidinium Functionalized Polytetrahydrofurans: Antimicrobial Properties in Solution and Application to Prepare Non Leaching Antimicrobial Surfaces.

Autor: Chattopadhyay, Subrata¹ Chattopadhyay@dwi.rwth-aachen.de, Heine, Elisabeth¹ Heine@dwi.rwth-aachen.de, Keul, Helmut¹ keul@dwi.rwth-aachen.de, Moeller, Martin¹ moeller@dwi.rwth-aachen.de

Publikováno v: Polymers (20734360). Sep2014, Vol. 6 Issue 9, p1618-1630. 15p. 1 Color Photograph, 4 Diagrams, 8 Charts, 1 Graph.

Zobrazit plný text záznamu