Zobrazeno 1 - 10
of 61
pro vyhledávání: '"E Lynette Wilson"'
Autor:
Jean-Christophe Pignon, Chiara Grisanzio, Ingrid Carvo, Lillian Werner, Meredith Regan, E Lynette Wilson, Sabina Signoretti
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128489 (2015)
There is evidence that stem cells and their progeny play a role in the development of the prostate. Although stem cells are also considered to give rise to differentiated progeny in the adult prostate epithelium ex vivo, the cohort of adult prostate
Externí odkaz:
https://doaj.org/article/c3a454f793b94968b7d9667c2b6c44fc
Autor:
Roy Blum, Rashmi Gupta, Patricia E Burger, Christopher S Ontiveros, Sarah N Salm, Xiaozhong Xiong, Alexander Kamb, Holger Wesche, Lisa Marshall, Gene Cutler, Xiangyun Wang, Jiri Zavadil, David Moscatelli, E Lynette Wilson
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Signals between stem cells and stroma are important in establishing the stem cell niche. However, very little is known about the regulation of any mammalian stem cell niche as pure isolates of stem cells and their adjacent mesenchyme are not readily
Externí odkaz:
https://doaj.org/article/edc2e4d8f0b5421992293e7bdc8e072e
Autor:
Roy Blum, Rashmi Gupta, Patricia E Burger, Christopher S Ontiveros, Sarah N Salm, Xiaozhong Xiong, Alexander Kamb, Holger Wesche, Lisa Marshall, Gene Cutler, Xiangyun Wang, Jiri Zavadil, David Moscatelli, E Lynette Wilson
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5722 (2009)
BACKGROUND:The global gene expression profiles of adult and fetal murine prostate stem cells were determined to define common and unique regulators whose misexpression might play a role in the development of prostate cancer. METHODOLOGY/PRINCIPAL FIN
Externí odkaz:
https://doaj.org/article/9ee26821c0a342a0927e05c63688aeea
Publikováno v:
Proceedings of the National Academy of Sciences. 110:20611-20616
The adult mouse prostate has a seemingly endless capacity for regeneration, and sonic hedgehog (SHH) signaling has been implicated in this stem cell-driven process. However, it is not clear whether SHH acts on the epithelium or stromal cells that sec
Autor:
Patricia E. Burger, David Moscatelli, Christopher S. Ontiveros, E. Lynette Wilson, Xiaozhong Xiong, Rashmi Gupta, Sarah N. Salm
Publikováno v:
Stem Cells. 27:2220-2228
We have shown previously that prostatic stem/progenitor cells can be purified from isolated prostate ducts, based on their high expression of the Sca-1 surface antigen. We now report that high levels of aldehyde dehydrogenase (ALDH) activity are pres
Publikováno v:
The Prostate. 68:893-901
The development of the murine prostate depends on reciprocal signals between the stroma and epithelium (1,2). The importance of stromal signals has been shown in prostate reconstitution experiments in which combinations of dissociated prostate epithe
Publikováno v:
The Prostate. 67:968-975
The prostate is androgen-sensitive, but hormone sensitivity differs in the different regions of the organ. After castration of rodents, the prostate involutes to one-third to one-fifth of its normal size. Involution is accompanied by apoptosis of pro
Autor:
David Moscatelli, Sarah N. Salm, Sandra Coetzee, Ken Goto, E. Lynette Wilson, Patricia E. Burger
Publikováno v:
The Journal of Cell Biology
We have previously shown that prostatic stem cells are located in the proximal region of mouse prostatic ducts. Here, we show that this region responds differently to transforming growth factor (TGF)-beta than the distal ductal region and that under
Autor:
Tetsuya Takao, Sarah N. Salm, Akira Tsujimura, David Moscatelli, E. Lynette Wilson, Sandra Coetzee
Publikováno v:
The Prostate. 51:175-188
BACKGROUND We have derived a panel of p53-null prostatic “basal” and “luminal” epithelial cell lines and their ras transformed counterparts to study stromal/epithelial interactions and the properties of tumors arising from “basal” and “