Zobrazeno 1 - 10
of 2 968
pro vyhledávání: '"E Lynch"'
Autor:
Maiko Matsui, Lauren E. Lynch, Isabella Distefano, Allison Galante, Aravind R. Gade, Hong-Gang Wang, Nicolas Gómez-Banoy, Patrick Towers, Daniel S. Sinden, Eric Q. Wei, Adam S. Barnett, Kenneth Johnson, Renan Lima, Alfonso Rubio-Navarro, Ang K. Li, Steven O. Marx, Timothy E. McGraw, Paul S. Thornton, Katherine W. Timothy, James C. Lo, Geoffrey S. Pitt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The canonical G406R mutation that increases Ca2+ influx through the CACNA1C-encoded CaV1.2 Ca2+ channel underlies the multisystem disorder Timothy syndrome (TS), characterized by life-threatening arrhythmias. Severe episodic hypoglycemia is
Externí odkaz:
https://doaj.org/article/c69ae191aabc414ca794e63e3df33805
Autor:
Mikaela G. Bell, Rhys H. Parry, Tricia S. E. Lee, Gervais Habarugira, Isabella E. McMahon, Madeline A. Thompson, Naphak Modhiran, Daniel Watterson, Jana Batovska, Stacey E. Lynch, Roy A. Hall, Jessica J. Harrison, Jody Hobson-Peters
Publikováno v:
npj Viruses, Vol 2, Iss 1, Pp 1-14 (2024)
Abstract Few insect-specific alphaviruses (ISA) have been discovered, with even fewer culturable to facilitate full characterisation. Here, we report the recovery of an infectious clone of Yada Yada virus (YYV)—a virus previously only detected by m
Externí odkaz:
https://doaj.org/article/95d7c8f8c92442fdbc6c44ca096b5821
Autor:
Myungkoo Kang, Rashi Sharma, Cesar Blanco, Daniel Wiedeman, Quentin Altemose, Patrick E. Lynch, Gil B. J. Sop Tagne, Yifei Zhang, Mikhail Y. Shalaginov, Cosmin-Constantin Popescu, Brandon M. Triplett, Clara Rivero-Baleine, Casey M. Schwarz, Anuradha M. Agarwal, Tian Gu, Juejun Hu, Kathleen A. Richardson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Ge–Sb–Se–Te chalcogenides, namely Se-substituted Ge–Sb–Te, have been developed as an alternative optical phase change material (PCM) with a high figure-of-merit. A need for the integration of such new PCMs onto a variety of photoni
Externí odkaz:
https://doaj.org/article/8048acebe74640ee8503b0e232f0a69e
Autor:
Yun Lu, Hailey A. Houson, Carlos A. Gallegos, Alessandro Mascioni, Fang Jia, Argin Aivazian, Patrick N. Song, Shannon E. Lynch, Tiara S. Napier, Ameer Mansur, Benjamin M. Larimer, Suzanne E. Lapi, Ariella B. Hanker, Anna G. Sorace
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-15 (2024)
Abstract Background Immune-positron emission tomography (PET) imaging with tracers that target CD8 and granzyme B has shown promise in predicting the therapeutic response following immune checkpoint blockade (ICB) in immunologically “hot” tumors.
Externí odkaz:
https://doaj.org/article/a67333033d1f4caf9696ae27352ee60a
Autor:
Andrew J. Graves, Joshua S. Danoff, Minah Kim, Samantha R. Brindley, Amalia M. Skyberg, Stephanie N. Giamberardino, Morgan E. Lynch, Brenda C. Straka, Travis S. Lillard, Simon G. Gregory, Jessica J. Connelly, James P. Morris
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract While chronological age is a strong predictor for health-related risk factors, it is an incomplete metric that fails to fully characterize the unique aging process of individuals with different genetic makeup, neurodevelopment, and environme
Externí odkaz:
https://doaj.org/article/0a7474c6984a4e0cbc2d95f4ae620d46
Autor:
Samantha K. Davis, Fan Jia, Quentin G. Wright, Md. Tanjir Islam, Andrew Bean, Daniel Layton, David T. Williams, Stacey E. Lynch
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Enhancing livestock biosecurity is critical to safeguard the livelihoods of farmers, global and local economies, and food security. Vaccination is fundamental to the control and prevention of exotic and endemic high-priority infectious livestock dise
Externí odkaz:
https://doaj.org/article/3aa233ebdc7646c093b64f5c1bd6f9a3
Autor:
Patrick N. Song, Shannon E. Lynch, Chloe T. DeMellier, Ameer Mansur, Carlos A. Gallegos, Brian D. Wright, Yolanda E. Hartman, Laura E. Minton, Suzanne E. Lapi, Jason M. Warram, Anna G. Sorace
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and hypoxia are associated with radioresistance. The goal of this study is to study the synergy of anti-HER2, trastuzumab, and anti-EGFR, cetuximab, an
Externí odkaz:
https://doaj.org/article/558a8968bead47b69cf936d5c973deaa
Autor:
Andrew Stuart Lane, Kate E. Lynch, Mark Arnold, Ilan Dar-Nimrod, James Morandini, Stefan A. Gawronski, Paul E. Griffiths
Publikováno v:
BMC Medical Education, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Knowledge of the genetic basis of health conditions can influence how the public perceives their own and others’ health. When there are known genetic associations for such conditions, genetic essentialist biases facilitate deter
Externí odkaz:
https://doaj.org/article/3dc7563cee184ad7a9cfa96ad607f3b0
Autor:
Rachel Thomas, Cillian E. Lynch, Jeff Debad, Christopher Campbell, Onyinyechi Chidomere, Joseph Kilianski, Kan Ding, Christopher Madden, Danielle K. Sandsmark, Ramon Diaz-Arrastia, Joshua W. Gatson
Publikováno v:
Neurotrauma Reports, Vol 4, Iss 1, Pp 655-662 (2023)
Each year in the United States, ?2.7 million persons seek medical attention for traumatic brain injury (TBI), of which ?85% are characterized as being mild brain injuries. Many different cell types in the brain are affected in these heterogeneous inj
Externí odkaz:
https://doaj.org/article/f9e06a3c8db5439ab51b4fc8bca415c1
Publikováno v:
Parasites & Vectors, Vol 16, Iss 1, Pp 1-13 (2023)
Abstract Background Ross River virus (RRV) is Australia’s most common and widespread mosquito-transmitted arbovirus and is of significant public health concern. With increasing anthropogenic impacts on wildlife and mosquito populations, it is impor
Externí odkaz:
https://doaj.org/article/c671ea55492c4eba99b4856297e5762d