Zobrazeno 1 - 2
of 2
pro vyhledávání: '"E L Klotz"'
Publikováno v:
The Journal of Immunology. 157:4458-4463
Previous experiments have suggested an important role for the Ig enhancers and transcription in targeting somatic hypermutation. To determine whether the requirement of the enhancers is Ig chain specific, we analyzed two lambda 2 light chain transgen
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(2)
We have characterized a novel substrate for somatic hypermutation, confirming that non-Ig sequences can be targeted for mutation and demonstrating that this substrate allows for the rapid assay for mutations. An artificial sequence containing alterna