Zobrazeno 1 - 10 of 72 pro vyhledávání: '"E L, Vitters"'
1
Gene expression analysis of murine and human osteoarthritis synovium reveals elevation of transforming growth factor β-responsive genes in osteoarthritis-related fibrosis
Autor: D F G, Remst, A B, Blom, E L, Vitters, R A, Bank, W B, van den Berg, E N, Blaney Davidson, P M, van der Kraan
Publikováno v: Arthritisrheumatology (Hoboken, N.J.). 66(3)
Synovial fibrosis is a major contributor to joint stiffness in osteoarthritis (OA). Transforming growth factor β (TGFβ), which is elevated in OA, plays a key role in the onset and persistence of synovial fibrosis. However, blocking of TGFβ in OA a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::274f04e677984a97abd6ce0586abdf7f
https://pubmed.ncbi.nlm.nih.gov/24574225
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2
Akademický článek
A Proteomic Approach to Determine Stem Cell Skeletal Differentiation Signature on Additive Manufactured Scaffolds.
Autor: Tomasina, Clarissa1 (AUTHOR), Mohren, Ronny2 (AUTHOR), Camarero‐Espinosa, Sandra1,3,4 (AUTHOR), Cillero‐Pastor, Berta1,2 (AUTHOR), Moroni, Lorenzo1 (AUTHOR) l.moroni@maastrichtuniversity.nl
Publikováno v: Small Science. Jul2024, Vol. 4 Issue 7, p1-16. 16p.
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3
Stimulation of articular cartilage repair in established arthritis by local administration of transforming growth factor-beta into murine knee joints
Autor: H L, Glansbeek, H M, van Beuningen, E L, Vitters, P M, van der Kraan, W B, van den Berg
Publikováno v: Laboratory investigation; a journal of technical methods and pathology. 78(2)
A severe consequence of rheumatoid arthritis is depletion of proteoglycans (PGs) from articular cartilage leading to functional impairment of this tissue. We investigated whether local administration of anabolic factors (transforming growth factors-b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::73651fd587cf60d3af71bec6fb211f20
https://pubmed.ncbi.nlm.nih.gov/9484711
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4
Early elevation of transforming growth factor-beta, decorin, and biglycan mRNA levels during cartilage matrix restoration after mild proteoglycan depletion
Autor: P M, van der Kraan, H L, Glansbeek, E L, Vitters, W B, van den Berg
Publikováno v: The Journal of rheumatology. 24(3)
To elucidate the role of transforming growth factor-beta (TGF-beta) and the small proteoglycans biglycan and decorin in the repair of articular cartilage after proteoglycan depletion.Limited and reversible proteoglycan depletion was induced by inject
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f68a8fa59b363490813b66662aa03ba3
https://pubmed.ncbi.nlm.nih.gov/9058663
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5
Stimulation of proteoglycan synthesis by triamcinolone acetonide and insulin-like growth factor 1 in normal and arthritic murine articular cartilage
Autor: P J, Verschure, P M, van der Kraan, E L, Vitters, W B, van den Berg
Publikováno v: The Journal of rheumatology. 21(5)
During experimentally induced arthritis, inhibition of proteoglycan synthesis is one of the mechanisms leading to cartilage destruction. Disturbed anabolic signalling might contribute to this impaired chondrocyte proteoglycan synthesis. We investigat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::91b3f4e3c80825cfa7712b45cd184e27
https://pubmed.ncbi.nlm.nih.gov/8064735
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6
Variable TGF-beta receptor expression regulates TGF-beta responses of articular chondrocytes
Autor: H L, Glansbeek, P M, van der Kraan, E L, Vitters, W B, van den Berg
Publikováno v: Agents and actions. Supplements. 39
TGF-beta inhibits the proteoglycan synthesis of freshly isolated articular chondrocytes while TGF-beta stimulates the proteoglycan synthesis of articular chondrocytes cultured for 14 days. To investigate if this differential effect was the result of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::acc4e035e78bcdf3887861d8e39ed396
https://pubmed.ncbi.nlm.nih.gov/8384401
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7
Proteoglycan synthesis and osteophyte formation in 'metabolically' and 'mechanically' induced murine degenerative joint disease: an in-vivo autoradiographic study
Autor: P M, van der Kraan, E L, Vitters, H M, van Beuningen, W B, van den Berg
Publikováno v: International journal of experimental pathology. 73(3)
We investigated the in-vivo proteoglycan synthesis in specific areas of murine knee joint articular cartilage after the induction of degenerative joint disease by means of 35S-sulphate autoradiography. Degenerative joint disease was induced either by
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::25ae70d927715446a5ccee285bed353d
https://pubmed.ncbi.nlm.nih.gov/1320394
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8
Degenerative knee joint lesions in mice after a single intra-articular collagenase injection. A new model of osteoarthritis
Autor: P M, van der Kraan, E L, Vitters, H M, van Beuningen, L B, van de Putte, W B, van den Berg
Publikováno v: Journal of experimental pathology (Oxford, England). 71(1)
A single intra-articular injection with bacterial collagenase in the right knee joints of 10-week-old male C57bl10 mice led to osteoarthritic lesions within a few weeks in these joints. The collagenase-induced osteoarthritis was characterized by seve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::12beccb5d71cc1d7bec87cfc134c5432
https://pubmed.ncbi.nlm.nih.gov/2155638
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10
Akademický článek
Age-related alterations in TGF beta signaling as a causal factor of cartilage degeneration in osteoarthritis.
Autor: van der Kraan, Peter M.1
Publikováno v: Bio-Medical Materials & Engineering. 2014 Supplement, Vol. 24, p75-80. 6p.
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