Zobrazeno 1 - 10
of 29
pro vyhledávání: '"E L, Travis"'
Publikováno v:
International journal of cancer. 96(1)
Intratracheal (IT) injection of the transgene for human manganese superoxide dismutase in plasmid/liposome (SOD2-PL) complex prior to irradiation protects C57BL/6J mice from whole lung irradiation-induced organizing alveolitis/fibrosis. Transgene mRN
Autor:
M W, Skwarchuk, E L, Travis
Publikováno v:
Radiation research. 149(1)
The use of three-dimensional treatment planning and volume-reduction techniques in radiotherapy has prompted the development of a number of mathematical models to describe the effect of changing treatment volume on the probability of associated compl
Autor:
C K, Haston, E L, Travis
Publikováno v:
Cancer research. 57(23)
From evidence of interpatient variability in normal tissue sensitivity to radiotherapy and from radiation studies using inbred mouse strains, it is hypothesized that individual variation in susceptibility to radiation-induced pulmonary fibrosis is ge
Publikováno v:
Cancer research. 57(10)
9-Amino-20(S)-camptothecin (9-AC) has demonstrated efficacy against several human cancer xenografts, including cancers of the colon, breast, lung, ovary, and stomach and malignant melanoma, and is currently undergoing Phase I clinical trials. In vitr
Autor:
C L, Dileto, E L, Travis
Publikováno v:
Radiation research. 146(1)
Radiation-induced pneumonitis and fibrosis in the lung after treatment to the thoracic cavity for malignant disease currently limit the maximum tolerated dose to that region. It has been suggested that heterogeneity in susceptibility to radiation-ind
Publikováno v:
Cancer research. 56(11)
Based on the range of patient responses to treatment, and on animal studies, it is hypothesized that individual variation in sensitivity to bleomycin-induced pulmonary fibrosis is controlled genetically. A genetic model has been developed by (a) esta
Autor:
D S, Followill, E L, Travis
Publikováno v:
Radiation research. 144(3)
These studies were undertaken to understand further the pathogenesis of consequential and primary fibrosis in mouse colon after irradiation. The distal 2.5 cm of colon of C3Hf/Kam mice was irradiated with either a single dose of 27 Gy or a split dose
Autor:
P G, Tee, E L, Travis
Publikováno v:
Cancer research. 55(2)
Basic fibroblast growth factor recently has been reported to confer significant protection against death from radiation pneumonitis in C3H/HeJ mice. Although the mechanism of this protection remains unknown, one hypothesis, based on in vitro data, is
Publikováno v:
Radiation research. 141(1)
Data published previously have shown that repair of sublethal damage in mouse lung proceeds with two significantly different repair half-times of 0.4 h and 4.0 h and that the fast component has approximately four times more weight than the slow compo
Autor:
Z X, Liao, E L, Travis
Publikováno v:
Radiation research. 139(3)
The effect of unilateral nephrectomy 24 h after irradiation on renal function and death with renal insufficiency as well as histopathological changes in the kidney was assessed. Single doses totaling 8-18 Gy were given bilaterally to unanesthetized f