Zobrazeno 1 - 10
of 50
pro vyhledávání: '"E L, Schwartz"'
Autor:
Avi I. Einzig, E. L. Schwartz, Peter H. Wiernik, Scott Wadler, Zhihang Lu, R. B. Diasio, Ruiwen Zhang, Joseph A. Sparano
Publikováno v:
Journal of Clinical Oncology. 11:1609-1617
PURPOSE To determine the maximum-tolerable dose (MTD) of fluorouracil (5-FU) administered as a low-dose, prolonged continuous intravenous infusion (PCI) plus interferon-alfa (IFN-alpha) that would permit treatment for at least 28 consecutive days, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::836397fcdec86894f416d24c786a96e0
https://doi.org/10.1200/jco.1993.11.8.1609
https://doi.org/10.1200/jco.1993.11.8.1609
Publikováno v:
Biochemical pharmacology. 62(9)
Thymidine phosphorylase (TP) catalyzes the reversible phosphorolysis of thymidine and other pyrimidine 2'-deoxyribonucleosides. In addition, TP has been shown to possess angiogenic activity in a number of in vitro and in vivo assays, and its angiogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee7d8c36de831c7faf2c4bfad74f01f7
https://pubmed.ncbi.nlm.nih.gov/11705459
https://pubmed.ncbi.nlm.nih.gov/11705459
Autor:
E L, Schwartz, M, Cohen
Publikováno v:
Journal of cognitive neuroscience. 12(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91a31185b8f562cd1b01c9ad1a1234ff
https://pubmed.ncbi.nlm.nih.gov/11054931
https://pubmed.ncbi.nlm.nih.gov/11054931
Autor:
S, Wadler, E L, Schwartz, P, Anderson, C D, Runowicz, L, Chuang, G, Del Priore, H, Hochster, G, Goldberg, A, Fields, G, Loewen, H, Haynes
Publikováno v:
The cancer journal from Scientific American. 5(3)
9-cis retinoic acid (ALRT 1057; 9cRA) is a promising new retinoid that binds to all known retinoic acid receptors (RAR and RXR), potentially providing it with a broader spectrum of biologic activity than either 13-cis retinoic acid or all-trans retin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ada083a08e6b9091f53c37bbb703e791
https://pubmed.ncbi.nlm.nih.gov/10367173
https://pubmed.ncbi.nlm.nih.gov/10367173
Autor:
R, Metzger, K, Danenberg, C G, Leichman, D, Salonga, E L, Schwartz, S, Wadler, H J, Lenz, S, Groshen, L, Leichman, P V, Danenberg
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(10)
The gene expression levels of the nucleoside cleavage enzyme/angiogenic factor thymidine phosphorylase (TP), also known as platelet-derived endothelial cell growth factor, were measured by quantitative reverse transcription-PCR in 38 pretreatment bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::14332590d844e862e50e157e99afef4f
https://pubmed.ncbi.nlm.nih.gov/9796967
https://pubmed.ncbi.nlm.nih.gov/9796967
Publikováno v:
Cancer research. 58(7)
The enzyme/cytokine thymidine phosphorylase/platelet-derived endothelial cell growth factor (TP/PD-ECGF) has diverse functions within cells, including the regulation of steady-state thymidine levels, the conversion of cancer chemotherapeutic agent 5-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28cc95acc8058f48f5596cbf9a2bdc7a
https://pubmed.ncbi.nlm.nih.gov/9537263
https://pubmed.ncbi.nlm.nih.gov/9537263
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(8)
We have used pulsed-field gel electrophoresis to examine 5-fluorouracil (5FU)-induced DNA double-strand breaks (DSBs), both with and without modulation by IFN-alpha2a (IFNalpha), in HT29 human colon adenocarcinoma cells. Although 24-h treatment with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1211a4ebf3ab49b871c25909b2e955d
https://pubmed.ncbi.nlm.nih.gov/9815814
https://pubmed.ncbi.nlm.nih.gov/9815814
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(6)
The enzyme/cytokine thymidine phosphorylase/platelet-derived endothelial cell growth factor (TP/PD-ECGF) has diverse functions within cells, including the regulation of steady-state thymidine levels, the conversion of the cancer chemotherapeutic agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::568c1f9b29b521e5703af66f858d4f6d
https://pubmed.ncbi.nlm.nih.gov/9815767
https://pubmed.ncbi.nlm.nih.gov/9815767
Autor:
S, Wadler, E L, Schwartz, H, Haynes, R, Rameau, A, Quish, J, Mandeli, R, Gallagher, S, Hallam, A, Fields, G, Goldberg, F, McGill, S, Jennings, R C, Wallach, C D, Runowicz
Publikováno v:
Cancer. 79(8)
Recent clinical trials with a combination of interferon (IFN alpha) and 13 cis-retinoic acid resulted in high response rates among women with locally advanced and metastatic carcinoma of the uterine cervix. The authors sought to amplify these observa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce9b759c51a6def40da2f80a228897b3
https://pubmed.ncbi.nlm.nih.gov/9118041
https://pubmed.ncbi.nlm.nih.gov/9118041
Autor:
K P, O'Boyle, Y, Wang, E L, Schwartz, D L, Regl, A, Einzig, J P, Dutcher, P H, Wiernik, S B, Horwitz
Publikováno v:
Cancer. 79(5)
Paclitaxel is an antimitotic agent isolated from the Pacific yew tree. It has demonstrated antitumor activity in several cancers and is the first of a new class of antineoplastic agents containing a taxane ring system. Its levels in serum and urine h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b72ae42e3de055b00ac4b580639884c6
https://pubmed.ncbi.nlm.nih.gov/9041166
https://pubmed.ncbi.nlm.nih.gov/9041166