Zobrazeno 1 - 10
of 23
pro vyhledávání: '"E L, Feldman"'
Autor:
E. M. Tank, C. Figueroa-Romero, L. M. Hinder, K. Bedi, H. C. Archbold, X. Li, K. Weskamp, N. Safren, X. Paez-Colasante, C. Pacut, S. Thumma, M. T. Paulsen, K. Guo, J. Hur, M. Ljungman, E. L. Feldman, S. J. Barmada
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
RNA instability may be a contributing factor in amyotrophic lateral sclerosis (ALS). Here the authors carry out genome-wide assessment of RNA synthesis and stability in cells derived from patients with C9orf72 ALS, sporadic ALS and healthy controls.
Externí odkaz:
https://doaj.org/article/a184e2bde9db4d10910de0c58efe84b6
Publikováno v:
Methods in molecular medicine. 2
The retinal pigment epithelium (RPE) is a layer of multipotential cells of neural ectoderm origin lying between Bruch's membrane and the neural retina. The RPE subserves several essential ocular functions, including phagocytosis of shed photoreceptor
Autor:
S C, Apfel, A K, Asbury, V, Bril, T M, Burns, J N, Campbell, C H, Chalk, P J, Dyck, E L, Feldman, H L, Fields, I A, Grant, J W, Griffin, C J, Klein, U, Lindblom, W J, Litchy, P A, Low, M, Melanson, J R, Mendell, M D, Merren, P C, O'Brien, M, Rendell, R A, Rizza, F J, Service, P K, Thomas, D, Walk, A K, Wang, K, Wessel, A J, Windebank, D, Ziegler, D W, Zochodne
Publikováno v:
Journal of the Neurological Sciences. 189:3-5
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 12(7)
Insulin-like growth factor I (IGF-I) protects cells from apoptosis primarily through the action of phosphatidylinositol-3 kinase and the downstream serine/threonine kinase Akt. The PTEN gene product, a protein which dephosphorylates phosphatidylinosi
Publikováno v:
Journal of neurochemistry. 76(3)
We previously reported that Schwann cells undergo apoptosis after serum withdrawal. Insulin-like growth factor-I, via phosphatidylinositol-3 kinase, inhibits caspase activation and rescues Schwann cells from serum withdrawal-induced apoptosis. In thi
Publikováno v:
The Journal of biological chemistry. 275(35)
Previously, we reported insulin-like growth factor-I (IGF-I) promotes motility and focal adhesion kinase (FAK) activation in neuronal cells. In the current study, we examined the role of IGF-I in Schwann cell (SC) motility. IGF-I increases SC process
Autor:
G, Comi, D, Fedele, C, Coscelli, D, Cucinotta, E L, Feldman, G, Ghirlanda, P, Negrin, F, Santeusanio, L, Maderna
Publikováno v:
Electroencephalography and clinical neurophysiology. Supplement. 50
Publikováno v:
Journal of neurobiology. 41(4)
Both neurons and glia succumb to programmed cell death (PCD) when deprived of growth factors at critical periods in development or following injury. Insulin-like growth factor-I (IGF-I) prevents apoptosis in neurons in vitro. To investigate whether I
Publikováno v:
Annals of the New York Academy of Sciences. 883
Insulin-like growth factor-I (IGF-I) promotes the proliferation and differentiation of Schwann cells (SC). We use SC/dorsal root ganglion neuron (DRG) cocultures to examine the effects of IGF-I on the interaction between axons and SC. As SC extend pr
Autor:
C M, Van Golen, E L, Feldman
Publikováno v:
Journal of cellular physiology. 182(1)
Neuroblastoma is a childhood tumor of the peripheral nervous system that remains largely uncurable by conventional methods. Mannitol induces apoptosis in neuroblastoma cell types and insulin-like growth factor I (IGF-I) protects these cells from hype