Zobrazeno 1 - 10
of 56
pro vyhledávání: '"E Kenneth, Parkinson"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 4092 (2024)
We explore the possibility that defects in genes associated with the response and repair of DNA double strand breaks predispose oral potentially malignant disorders (OPMD) to undergo malignant transformation to oral squamous cell carcinoma (OSCC). De
Externí odkaz:
https://doaj.org/article/8e634557fcdc4b9281b0ec0bfb4af455
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Many of the characteristics ascribed to cancer-associated fibroblasts (CAFs) are shared by activated, autophagic and senescent fibroblasts. Whilst most oral squamous cell carcinomas (OSCCs) are genetically unstable (GU-OSCC), genetically sta
Externí odkaz:
https://doaj.org/article/2148c927ce1b407c85b7d5e10ed48543
Publikováno v:
Biology, Vol 12, Iss 1, p 103 (2023)
An escape from cellular senescence through the development of unlimited growth potential is one of the hallmarks of cancer, which is thought to be an early event in carcinogenesis. In this review, we propose that the molecular effectors of senescence
Externí odkaz:
https://doaj.org/article/d765488cc51a45f0a59141323b4d0a52
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/9f962be5ad6a4a9dbf9dadfd350a5b1a
Autor:
Sebastian Haferkamp, Konstantin Drexler, Marianne Federlin, Hans J. Schlitt, Mark Berneburg, Jerzy Adamski, Andreas Gaumann, Edward K. Geissler, Vadivel Ganapathy, E. Kenneth Parkinson, Maria E. Mycielska
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Cancer cells need excess energy and essential nutrients/metabolites not only to divide and proliferate but also to migrate and invade distant organs for metastasis. Fatty acid and cholesterol synthesis, considered a hallmark of cancer for anabolism a
Externí odkaz:
https://doaj.org/article/c535675aec8b489abe46ee49c300d3a5
Autor:
E. Kenneth Parkinson, Jerzy Adamski, Grit Zahn, Andreas Gaumann, Fabian Flores-Borja, Christine Ziegler, Maria E. Mycielska
Publikováno v:
Cancer Metastasis Rev., DOI: 10.1007/s10555-021-10007-1 (2021)
It is well established that cancer cells acquire energy via the Warburg effect and oxidative phosphorylation. Citrate is considered to play a crucial role in cancer metabolism by virtue of its production in the reverse Krebs cycle from glutamine. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf7b59659e08f50312499b82baf230c
https://epub.uni-regensburg.de/51272/
https://epub.uni-regensburg.de/51272/
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133745 (2015)
Limited options for the treatment of cartilage damage have driven the development of tissue engineered or cell therapy alternatives reliant on ex vivo cell expansion. The study of chondrogenesis in primary cells is difficult due to progressive cellul
Externí odkaz:
https://doaj.org/article/bcc6e6d001a146699f5c694d09d85540
Autor:
Steven D. Bryce, Vivienne Morrison, Nicola J. Craig, Nicholas R. Forsyth, Sara A. Fitzsimmons, Hazel Ireland, Andrew P. Cuthbert, Robert F. Newbold, E. Kenneth Parkinson
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 4, Iss 6, Pp 544-550 (2002)
Human chromosome 4 was previously shown to elicit features of senescence when introduced into cell lines that map to complementation group B for senescence, including HeLa cells. Subsequently, a DNA segment encoding the pseudogene Mortality Factor 4
Externí odkaz:
https://doaj.org/article/a6179be447d349699fd49d61c5fd5ae5
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Many of the characteristics ascribed to cancer-associated fibroblasts (CAFs) are shared by activated, autophagic and senescent fibroblasts. Whilst most oral squamous cell carcinomas (OSCCs) are genetically unstable (GU-OSCC), genetically stable varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf52db5819f12b130798571495b7903
https://doi.org/10.1038/s41598-020-79789-8
https://doi.org/10.1038/s41598-020-79789-8
Autor:
Sebastian, Haferkamp, Konstantin, Drexler, Marianne, Federlin, Hans J, Schlitt, Mark, Berneburg, Jerzy, Adamski, Andreas, Gaumann, Edward K, Geissler, Vadivel, Ganapathy, E Kenneth, Parkinson, Maria E, Mycielska
Publikováno v:
Front. Cell Dev. Biol. 8:602476 (2020)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
Cancer cells need excess energy and essential nutrients/metabolites not only to divide and proliferate but also to migrate and invade distant organs for metastasis. Fatty acid and cholesterol synthesis, considered a hallmark of cancer for anabolism a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f164230d585f796c1548dc4389d1b08
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=60842
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=60842