Zobrazeno 1 - 10
of 2 287
pro vyhledávání: '"E Kelley"'
Autor:
Salik Hussain, Nairrita Majumder, Md Habibul Hasan Mazumder, Sara E. Lewis, Olanrewaju Olapeju, Murugesan Velayutham, Md Shahrier Amin, Kathleen Brundage, Eric E. Kelley, Jeroen Vanoirbeek
Publikováno v:
Redox Biology, Vol 76, Iss , Pp 103330- (2024)
The ability of air pollution to induce acute exacerbation of asthma is well documented. However, the ability of ozone (O3), the most reactive gaseous component of air pollution, to function as a modulator during sensitization is not well established.
Externí odkaz:
https://doaj.org/article/baacc4854cc84a069ee556f502f997ac
Autor:
Nicholas R. Carr, Timothy M. Bahr, Robin K. Ohls, Sarah M. Tweddell, David S. Morris, Terry Rees, Sarah J. Ilstrup, Walter E. Kelley, Robert D. Christensen
Publikováno v:
American Journal of Perinatology Reports, Vol 14, Iss 02, Pp e129-e132 (2024)
Externí odkaz:
https://doaj.org/article/6080bd147084427d98b38b276e386dcd
Autor:
Julie A. Griffith, Rachel D. King, Allison C. Dunn, Sara E. Lewis, Brooke A. Maxwell, Timothy R. Nurkiewicz, William T. Goldsmith, Eric E. Kelley, Elizabeth C. Bowdridge
Publikováno v:
Advances in Redox Research, Vol 10, Iss , Pp 100090- (2024)
The placenta plays a critical role in nutrient-waste exchange between the maternal and fetal circulation, and thus impacts fetal growth and development. We have previously shown that nano-titanium dioxide (nano-TiO2) inhalation exposure during gestat
Externí odkaz:
https://doaj.org/article/462084994b304c8d88396bb92fb0046a
Autor:
Md Habibul Hasan Mazumder, Jasleen Gandhi, Nairrita Majumder, Lei Wang, Robert Ian Cumming, Sydney Stradtman, Murugesan Velayutham, Quincy A. Hathaway, Jonathan Shannahan, Gangqing Hu, Timothy R. Nurkiewicz, Robert M. Tighe, Eric E. Kelley, Salik Hussain
Publikováno v:
Particle and Fibre Toxicology, Vol 20, Iss 1, Pp 1-21 (2023)
Abstract Background Microbial dysbiosis is a potential mediator of air pollution-induced adverse outcomes. However, a systemic comparison of the lung and gut microbiome alterations and lung-gut axis following air pollution exposure is scant. In this
Externí odkaz:
https://doaj.org/article/e583f09a8a5a44668f3507be711a941b
Autor:
Evan R. DeVallance, Heidi M. Schmidt, Madison Seman, Sara E. Lewis, Katherine C. Wood, Schuyler D. Vickers, Scott A. Hahn, Murugesan Velayutham, Emily A. Hileman, Dario A. Vitturi, Roberta Leonardi, Adam C. Straub, Eric E. Kelley
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102866- (2023)
We recently reported a previously unknown salutary role for xanthine oxidoreductase (XOR) in intravascular heme overload whereby hepatocellular export of XOR to the circulation was identified as a seminal step in affording protection. However, the ce
Externí odkaz:
https://doaj.org/article/87ca64a023a542648045412108a3db24
Autor:
Megan E Kelley, Adi Y Berman, David R Stirling, Beth A Cimini, Yu Han, Shantanu Singh, Anne E Carpenter, Tarun M Kapoor, Gregory P Way
Publikováno v:
eLife, Vol 12 (2023)
Drug resistance is a challenge in anticancer therapy. In many cases, cancers can be resistant to the drug prior to exposure, that is, possess intrinsic drug resistance. However, we lack target-independent methods to anticipate resistance in cancer ce
Externí odkaz:
https://doaj.org/article/cfac481b631b4e0093cc24ca0e9a858b
Autor:
Younes Sadat-Nejad, Marlee M. Vandewouw, R. Cardy, J. Lerch, M. J. Taylor, A. Iaboni, C. Hammill, B. Syed, J. A. Brian, E. Kelley, M. Ayub, J. Crosbie, R. Schachar, S. Georgiades, R. Nicolson, E. Anagnostou, A. Kushki
Publikováno v:
Frontiers in Child and Adolescent Psychiatry, Vol 2 (2023)
IntroductionAttention-deficit/hyperactivity disorder (ADHD) and autism are multi-faceted neurodevelopmental conditions with limited biological markers. The clinical diagnoses of autism and ADHD are based on behavioural assessments and may not predict
Externí odkaz:
https://doaj.org/article/0f612ea801b740a69623bfc32ec5821f
Autor:
Margaret Wu, Ester Carballo-Jane, Haihong Zhou, Peter Zafian, Ge Dai, Mindy Liu, Julie Lao, Terri Kelly, Dan Shao, Judith Gorski, Dmitri Pissarnitski, Ahmet Kekec, Ying Chen, Stephen F. Previs, Giovanna Scapin, Yacob Gomez-Llorente, Scott A. Hollingsworth, Lin Yan, Danqing Feng, Pei Huo, Geoffrey Walford, Mark D. Erion, David E. Kelley, Songnian Lin, James Mu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/d6d3fdb3039843b9b530ac94e6eb34d2
Autor:
Heidi M. Schmidt, Evan R. DeVallance, Sara E. Lewis, Katherine C. Wood, Gowtham K. Annarapu, Mara Carreño, Scott A. Hahn, Madison Seman, Brooke A. Maxwell, Emily A. Hileman, Julia Z. Xu, Murugesan Velayutham, Werner J. Geldenhuys, Dario A. Vitturi, Sruti Shiva, Eric E. Kelley, Adam C. Straub
Publikováno v:
Redox Biology, Vol 62, Iss , Pp 102636- (2023)
Xanthine oxidase (XO) catalyzes the catabolism of hypoxanthine to xanthine and xanthine to uric acid, generating oxidants as a byproduct. Importantly, XO activity is elevated in numerous hemolytic conditions including sickle cell disease (SCD); howev
Externí odkaz:
https://doaj.org/article/fc1d13f5ed7a4f76bf1f12017427f9c4
Autor:
Xena M. Williams, Alec T. Bossert, Evan Devalance, Sara E. Lewis, Michael R. Gunther, Eric E. Kelley
Publikováno v:
Advances in Redox Research, Vol 7, Iss , Pp 100058- (2023)
One electron reduction of nitrite (NO2−) has been determined to be a significant, noncanonical source of nitric oxide (NO) with molybdopterin enzymes being identified as critical to this process. Of the molybdopterin enzymes identified as NO2− re
Externí odkaz:
https://doaj.org/article/35f25ec045434662af80bb4d656974c6