Zobrazeno 1 - 10
of 55
pro vyhledávání: '"E K Weir"'
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 75:889-897
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::085c5197dddf7a0160b256aa4d7ac975
https://doi.org/10.1139/y97-111
https://doi.org/10.1139/y97-111
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 264:H1478-H1484
Oxygen radicals have been implicated in the pathogenesis of myocardial injury. Enhanced chemiluminescence is a sensitive technique for continuous nondestructive measurement of oxygen radical generation. Using an isolated perfused rat heart model, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170dce847a291e5a95579474420cf73b
https://doi.org/10.1152/ajpheart.1993.264.5.h1478
https://doi.org/10.1152/ajpheart.1993.264.5.h1478
Publikováno v:
American Journal of Physiology-Cell Physiology. 262:C882-C890
Cellular mechanisms responsible for hypoxic pulmonary vasoconstriction were investigated in pulmonary arterial cells, isolated perfused lung, and pulmonary artery rings. Three K+ channel antagonists, Leiurus quinquestriatus venom, tetraethylammonium,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e4e73eedbc1285f8af0559c18ef112
https://doi.org/10.1152/ajpcell.1992.262.4.c882
https://doi.org/10.1152/ajpcell.1992.262.4.c882
Publikováno v:
British journal of pharmacology. 155(3)
Specialized tissues that sense acute changes in the local oxygen tension include type 1 cells of the carotid body, neuroepithelial bodies in the lungs, and smooth muscle cells of the resistance pulmonary arteries and the ductus arteriosus (DA). Hypox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41d4a99747ef34b91c701839cb71d077
https://pubmed.ncbi.nlm.nih.gov/18641675
https://pubmed.ncbi.nlm.nih.gov/18641675
Autor:
E D, Michelakis, E K, Weir
Publikováno v:
Clinics in chest medicine. 22(3)
Chronic hypoxic pulmonary arterial hypertension, APAH, and PPAH are characterized by vasoconstriction and vascular remodeling and are associated with decreased Kv currents in PA smooth muscle cells. Although Kv2.1 is less well studied, it seems that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3846290e38badd41396d757ecdba8fb4
https://pubmed.ncbi.nlm.nih.gov/11590838
https://pubmed.ncbi.nlm.nih.gov/11590838
Publikováno v:
Advances in experimental medicine and biology. 475
Small, muscular pulmonary arteries (PAs) constrict within seconds of the onset of alveolar hypoxia, diverting blood flow to better-ventilated lobes, thereby matching ventilation to perfusion and optimizing systemic PO2. This hypoxic pulmonary vasocon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7f85d7ec8cef994f17871a6fc5606182
https://pubmed.ncbi.nlm.nih.gov/10849663
https://pubmed.ncbi.nlm.nih.gov/10849663
Adenosine and selective reduction of pulmonary vascular resistance in primary pulmonary hypertension
Publikováno v:
Circulation. 84:1437-1439
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e452ad23e788a759089c03aa95c14a47
https://doi.org/10.1161/01.cir.84.3.1437
https://doi.org/10.1161/01.cir.84.3.1437
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 291(3)
Appetite suppressants, such as dexfenfluramine (dex), are associated with primary pulmonary hypertension, valvular heart disease, and systemic vascular complications, such as coronary, cerebral, or mesenteric ischemia. These drugs suppress appetite b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb86ccf06f280fc3aa79e6300e896189
https://pubmed.ncbi.nlm.nih.gov/10565835
https://pubmed.ncbi.nlm.nih.gov/10565835
Publikováno v:
Life sciences. 65(11)
G proteins are membrane-bound regulatory proteins which modulate the activity of ion channels and other effector systems. The GTP and GDP analogs GTP (gammaS) and GDP (betaS) have been used to study the role of G proteins in numerous physiologic syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b8afde0337dc26c623b3ee58a18dce62
https://pubmed.ncbi.nlm.nih.gov/10503929
https://pubmed.ncbi.nlm.nih.gov/10503929
Publikováno v:
Chest. 114
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0322cf8393e06cc7e9da4d6cbc5cbbe9
https://pubmed.ncbi.nlm.nih.gov/9676606
https://pubmed.ncbi.nlm.nih.gov/9676606