Zobrazeno 1 - 10
of 13
pro vyhledávání: '"E K Bayne"'
Autor:
H R Williams, C F Harper, John G. Flanagan, J R Weidner, E K Bayne, N I Hutchinson, S A Donatelli, I I Singer, L A Hoerrner, Michael W. Lark, L. S. Lohmander, R A Mumford
Publikováno v:
Scopus-Elsevier
To examine the activity of matrix metalloproteinases (MMPs) and aggrecanase in control and diseased human articular cartilage, metabolic fragments of aggrecan were detected with monospecific antipeptide antibodies. The distribution and quantity of MM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e050bd7b9d0c85b513d9581a9cacc457
https://doi.org/10.1172/jci119526
https://doi.org/10.1172/jci119526
Publikováno v:
The Journal of Immunology. 145:4154-4166
Human IL-1 alpha, IL-1 beta, and TNF-alpha mRNA expression was examined in peripheral blood monocytes (PBM) from normal individuals and in primary synoviocytes isolated from patients with rheumatoid arthritis by Northern blot and in situ hybridizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d36861666486cc9e8926b24c43e352b
https://doi.org/10.4049/jimmunol.145.12.4154
https://doi.org/10.4049/jimmunol.145.12.4154
Autor:
E K, Bayne, J, Flanagan, M, Einstein, J, Ayala, B, Chang, B, Azzolina, D A, Whiting, R A, Mumford, D, Thiboutot, I I, Singer, G, Harris
Publikováno v:
The British journal of dermatology. 141(3)
The predominant form of 5alpha-reductase (5aR) in human scalp is 5aR1. None the less, clinical studies have shown that finasteride, a selective inhibitor of 5aR2, decreases scalp dihydrotestosterone and promotes hair growth in men with androgenetic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08d6fa3d48ea6032b3829c24b870b7ee
https://pubmed.ncbi.nlm.nih.gov/10583052
https://pubmed.ncbi.nlm.nih.gov/10583052
Publikováno v:
Arthritis and rheumatism. 42(6)
Two major cleavage sites, one mediated by metalloproteinases (MMPs) and the other by an as-yet unidentified enzyme termed aggrecanase, have been observed in aggrecan. To learn more about the relative contribution of these enzymes during cartilage deg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e1277d8454269fcb41469e8a281e9ec6
https://pubmed.ncbi.nlm.nih.gov/10366105
https://pubmed.ncbi.nlm.nih.gov/10366105
Publikováno v:
Arthritis and rheumatism. 41(4)
To investigate the relationship between occurrence of the matrix metalloproteinase-generated neoepitope VDIPEN and proteoglycan (PG) loss in arthritis, and to examine the role of interleukin-1 (IL-1) in VDIPEN expression.VDIPEN expression was investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::61d83973f0c16bcd0942d4a7a7dd2242
https://pubmed.ncbi.nlm.nih.gov/9550473
https://pubmed.ncbi.nlm.nih.gov/9550473
Autor:
J S, Mudgett, N I, Hutchinson, N A, Chartrain, A J, Forsyth, J, McDonnell, I I, Singer, E K, Bayne, J, Flanagan, D, Kawka, C F, Shen, K, Stevens, H, Chen, M, Trumbauer, D M, Visco
Publikováno v:
Arthritis and rheumatism. 41(1)
It has long been proposed that stromelysin is one of the major degradative matrix metalloproteinases responsible for the loss of cartilage in rheumatoid arthritis (RA) and osteoarthritis (OA). This hypothesis was tested by examining the arthritic paw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2e3a86f5cb5e87a1c9cdc6022209701
https://pubmed.ncbi.nlm.nih.gov/9433876
https://pubmed.ncbi.nlm.nih.gov/9433876
Publikováno v:
Acta orthopaedica Scandinavica. Supplementum. 266
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::219fc96fc885c1932850d21cef2c0df9
https://pubmed.ncbi.nlm.nih.gov/8553869
https://pubmed.ncbi.nlm.nih.gov/8553869
Autor:
M W, Lark, K A, MacNaul, S, Donatelli, J, McDonnell, L A, Hoerrner, K A, Stevens, C A, Saphos, E K, Bayne, N I, Hutchinson, V L, Moore
Publikováno v:
The Journal of rheumatology. 21(9)
To study the effects of the intraarticular injection of canine monocyte conditioned medium (cMCM) into dogs on proteoglycan fragment and stromelysin levels in the joint.cMCM was injected intraarticularly into dogs, and the levels of proteoglycan frag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e71a1d6afb9804496e6996c1c40c6edf
https://pubmed.ncbi.nlm.nih.gov/7799356
https://pubmed.ncbi.nlm.nih.gov/7799356
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 145(12)
Human IL-1 alpha, IL-1 beta, and TNF-alpha mRNA expression was examined in peripheral blood monocytes (PBM) from normal individuals and in primary synoviocytes isolated from patients with rheumatoid arthritis by Northern blot and in situ hybridizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de9b857bfcfddd26868748fa59f1b657
https://pubmed.ncbi.nlm.nih.gov/2258613
https://pubmed.ncbi.nlm.nih.gov/2258613
Autor:
D D Wood, E K Bayne, M B Goldring, M Gowen, D Hamerman, J L Humes, E J Ihrie, P E Lipsky, M J Staruch
Publikováno v:
The Journal of Immunology. 134:895-903
The supernatants of human monocytes incubated with endotoxin are able to stimulate the proliferation of murine thymocytes in the presence of PHA. This is known as LAF (lymphocyte activating factor) activity and is a characteristic activity of interle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef8730cbc42b3d91583650e4b7706ea4
https://doi.org/10.4049/jimmunol.134.2.895
https://doi.org/10.4049/jimmunol.134.2.895