Zobrazeno 1 - 10
of 24
pro vyhledávání: '"E K, Kruithof"'
Publikováno v:
Thrombosis and haemostasis. 86(2)
Endothelial cell migration is stimulated by members of the vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) families, and is dependent on extracellular proteolytic activity provided by enzymes of the plasminogen act
Autor:
S, Dunoyer-Geindre, E K, Kruithof, B, Galve-de Rochemonteix, C, Rosnoblet, J, Gruenberg, G, Reber, P, de Moerloose
Publikováno v:
Thrombosis and haemostasis. 85(5)
Antiphospholipid antibodies (APLA) are associated with thrombophilia and recurrent pregnancy loss. Different mechanisms have been proposed to explain their pathogenic effects and among them, we have previously shown that APLA accumulate in late endos
Publikováno v:
Thrombosis and haemostasis. 83(2)
The low density lipoprotein receptor-related protein (LRP) is a multiligand clearance receptor that removes free tissue-type plasminogen activator (t-PA) or complexes of t-PA with plasminogen activator inhibitor type 1 (PAI-1) from the blood circulat
Publikováno v:
Thrombosis and haemostasis. 82(6)
Tissue factor pathway inhibitor (TFPI), the major downregulator of the procoagulant activity of tissue factor (TF), is synthesised by endothelial cells (EC) and acutely released in vitro after thrombin stimulation. Expression of TF on EC and subseque
Publikováno v:
Thrombosis and haemostasis. 77(5)
Disseminated intravascular coagulation (DIC) may lead to severe thrombotic or hemorrhagic complications. The present work was undertaken to study the effect of interleukin 6 (IL-6) on variations of key coagulation and fibrinolytic parameters in plasm
Publikováno v:
American journal of medical genetics. 74(2)
The presence of one or two apoliprotein E4 (apoE4) alleles constitutes a major risk factor for Alzheimer's disease (AD) and coronary heart disease (CHD). Numerous observations have suggested that misregulation of proteases may be instrumental in both
Publikováno v:
International journal of cancer. 70(4)
Involvement of extravascular sites, in particular infiltration of the central nervous system, is a frequent complication of T-lymphoblastic leukemia and contributes to leukemia-associated morbidity. In this report, we studied the contribution of plas
Publikováno v:
Thrombosis and haemostasis. 77(2)
Disseminated intravascular coagulation (DIC) is a frequent complication of septicemia or tissue injury and may be accompanied by elevations of interleukin-6, a mediator of the acute phase response. It is not known whether thrombin or fibrin depositio
Autor:
C, Camani, E K, Kruithof
Publikováno v:
International journal of hematology. 60(2)
Hepatic clearance is one of the principal mechanisms regulating plasma concentrations of tissue-type plasminogen activator (t-PA). Two distinct pathways appear to be involved. Liver endothelial cells and Kupffer cells clear t-PA via the mannose recep
Publikováno v:
European cytokine network. 5(3)
To assess the effect of interleukin-6 (IL-6) on the coagulation and the fibrinolytic systems, we administered a single subcutaneous injection of recombinant glycosylated human interleukin-6 (r-hIL-6) 100 micrograms per kg body weight) to four baboons