Zobrazeno 1 - 10
of 40
pro vyhledávání: '"E James Delikatny"'
Autor:
Mitchell G Bryski, Lydia G Frenzel-Sulyok, E James Delikatny, Charuhas Deshpande, Leslie A Litzky, Sunil Singhal
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252731 (2021)
BackgroundIntraoperative frozen section (FS) consultation is an important tool in surgical oncology that suffers from sampling error because the pathologist does not always know where to perform a biopsy of the surgical specimen. Intraoperative molec
Externí odkaz:
https://doaj.org/article/9b085d30b461440480281eb3e77ba32f
Autor:
Alejandro D. Arroyo, Andrea E. Guzman, Alexander V. Kachur, Anatoliy V. Popov, E. James Delikatny
Publikováno v:
Frontiers in Physics, Vol 9 (2021)
This paper describes functional fluorinated bioactivatable molecules to study cancer metabolism using Cerenkov imaging. Resazurin (RA), or Alamar Blue, is a commonly used viability dye and redox sensor. Under reductive conditions or by the action of
Externí odkaz:
https://doaj.org/article/16978d1c68514c5a8c43b37b68526993
Autor:
Chongzhao Ran, James R. Mansfield, Mingfeng Bai, Nerissa T. Viola, Abhishek Mahajan, E. James Delikatny
Publikováno v:
Molecular Imaging and Biology. 25:240-264
Autor:
Theresa M. Busch, Alejandro D. Arroyo, Benjamin K. Liebov, Natalia I. Rubtsova, Michael C Hart, Nadia Anikeeva, Anatoliy V. Popov, Sanghoon Chong, Joann Miller, E. James Delikatny, Sofya A Osharovich, Jeffrey M. Cochran, Min Yuan, Arjun G. Yodh
Publikováno v:
Bioconjugate Chemistry. 32:1852-1863
New exogenous probes are needed for both imaging diagnostics and therapeutics. Here, we introduce a novel nanocomposite near-infrared (NIR) fluorescent imaging probe and test its potency as a photosensitizing agent for photodynamic therapy (PDT) agai
Autor:
Anatoliy V. Popov, Sarah J. Saylor, Alexander V. Kachur, Andrea E. Guzman, E. James Delikatny, Alejandro D. Arroyo
Publikováno v:
J Fluor Chem
In this paper, we report the synthesis and characterization of fluorinated derivatives of naphthofluorescein (NF), a fluorescent pH-sensitive probe that can be used for functional Cerenkov imaging. The compounds were prepared using electrophilic fluo
Autor:
Charuhas Deshpande, Lydia G. Frenzel-Sulyok, Mitchell G. Bryski, Leslie A. Litzky, Sunil Singhal, E. James Delikatny
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252731 (2021)
PLoS ONE
PLoS ONE
Background Intraoperative frozen section (FS) consultation is an important tool in surgical oncology that suffers from sampling error because the pathologist does not always know where to perform a biopsy of the surgical specimen. Intraoperative mole
Autor:
Benjamin K. Liebov, Natalia I. Rubtsova, E. James Delikatny, Alejandro D. Arroyo, Sofya A Osharovich, Anatoliy V. Popov
Publikováno v:
ACS Omega
ACS Omega, Vol 3, Iss 6, Pp 6867-6873 (2018)
ACS Omega, Vol 3, Iss 6, Pp 6867-6873 (2018)
The near-infrared fluorescent activatable smart probe Pyro-phosphatidylethanolamine (PtdEtn)-QSY was synthesized and observed to selectively fluoresce in the presence of phosphatidylcholine-specific phospholipase C (PC-PLC). PC-PLC is an important bi
Autor:
Alexander V. Kachur, E. James Delikatny, Anatoliy V. Popov, Alejandro D. Arroyo, Sarah J. Saylor, Nikaela W. Bryan
Publikováno v:
Journal of Fluorine Chemistry. 200:146-152
Direct electrophilic fluorination using molecular fluorine gas is used in organic synthesis to create novel fluorine-containing compounds with potential beneficial activity that could not be obtained by nucleophilic substitution. In this paper, we re
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1862(4):651-661
Neurodegenerative disorders represent the culmination of numerous insults including oxidative stress. The long etiology of most of these disorders suggests that lessening the effects of one or more of the insults could significantly delay disease ons
Autor:
Michael G. Chiorazzo, Anatoliy V. Popov, Berit Johansen, E. James Delikatny, Hanna Maja Tunset, Siver Andreas Moestue
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Cytosolic phospholipase A2α (cPLA2α) has been shown to be elevated in breast cancer and is a potential biomarker in the differentiation of molecular sub-types. Using a cPLA2α activatable fluorophore, DDAO arachidonate, we explore its ability to fu