Zobrazeno 1 - 10
of 13
pro vyhledávání: '"E J Yurkow"'
Publikováno v:
British Journal of Cancer
Calmodulin-dependent protein kinase III (CaM kinase III, elongation factor-2 kinase) is a unique member of the Ca2+/CaM-dependent protein kinase family. Activation of CaM kinase III leads to the selective phosphorylation of elongation factor 2 (eEF-2
Publikováno v:
Biochemical Journal. 291:375-381
Transmembrane Ca2+ influx is recognized as a universal second messenger that transduces T-cell activation signals to cytoplasm and nucleus, thereby stimulating transcription and cell division. To examine the role of endogenous factors that regulate m
Publikováno v:
Journal of toxicology and environmental health. Part A. 60(4)
The relationship between metallothionein levels and concentrations of several metals and radionuclides was examined in liver tissues of raccoons (Procyon lotor, n = 47) from the Department of Energy's Savannah River Site in South Carolina to determin
Publikováno v:
Journal of biomedical materials research. 50(3)
Using a rodent air pouch, the inflammatory responses to biomaterials with distinct physical properties and chemical compositions were compared. The polymers examined were expanded poly(tetrafluoroethylene) (ePTFE), silicone, low-density polyethylene
Publikováno v:
Oncology Reports.
We have studied the effects of phytoestrogens (genistein, quercetin, daidzein, biochanin A and kaempferol) on proliferation, cell cycle kinetics, and apoptosis of MDA-MB-468 breast cancer cells. Genistein and quercetin inhibited cell growth with IC50
Publikováno v:
Cytometry. 37(1)
Measurement of vascular cell proliferation in animal models of hypertension is currently accomplished by demonstrating [(3)H]-thymidine ([(3)H]-dT) incorporation into DNA using autoradiography. This method, however, is labor intensive, requires radio
Publikováno v:
Oncology reports. 5(5)
Estradiol stimulates the growth of a majority of human breast tumors containing the estrogen receptors (ERs), proteins that mediates estrogen function. Opposing effects of estradiol have been found in cells expressing endogenous ER and those containi
Autor:
R D, Huhn, E J, Yurkow, R, Tushinski, L, Clarke, M G, Sturgill, R, Hoffman, W, Sheay, R, Cody, C, Philipp, D, Resta, M, George
Publikováno v:
Experimental hematology. 24(7)
To identify a precisely timed and safe protocol for progenitor cell mobilization, we studied the effects of rhIL-3 and rhG-CSF administration to normal volunteers. rhG-CSF 5 micrograms/kg/d was administered subcutaneously (s.c.) for 7 consecutive day
Autor:
G, Kim, E J, Yurkow
Publikováno v:
Cancer research. 56(9)
Chromium is an important industrial metal, an environmental pollutant, and a human carcinogen. To investigate the mechanisms of chromium-induced carcinogenesis, activation of mitogen-activated protein (MAP) kinases ERK1 and ERK2 was examined in rat h
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 273(2)
Topical application of beta-naphthoflavone to CD-1 mice induced an 87-fold increase in epidermal 7-ethoxyresorufin O-dealkylation activity per cell and a many-fold increase in epidermal cytochrome P-4501A1 (CYP1A1) concentration. Flow cytometric anal