Výsledky vyhledávání - "E J Weening-Verhoeff"

Complementation between urokinase-producing and receptor-producing cells in extracellular matrix degradation

Autor: Keld Danø, Francesco Blasi, E J Weening-Verhoeff, Paul H.A. Quax, Jan H. Verheijen, Nina Pedersen, M T Masucci

Publikováno v: Europe PubMed Central

The respective roles of urokinase plasminogen activator (u-PA) and the u-PA receptor in extracellular matrix degradation was investigated. Human pro-u-PA and the human u-PA receptor were expressed independently by two different mouse LB6 cell lines.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5379c6bb27b0aa57ff6870b76e7bcd6a
https://doi.org/10.1091/mbc.2.10.793

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Involvement of aspartic and glutamic residues in kringle-2 of tissue-type plasminogen activator in lysine binding, fibrin binding and stimulation of activity as revealed by chemical modification and oligonucleotide-directed mutagenesis

Autor: Jan H. Verheijen, R.T.J. van Leeuwen, Edward F. Rehberg, Keith R. Marotti, E J Weening-Verhoeff, Paul H.A. Quax

Publikováno v: "Protein Engineering, Design and Selection". 4:191-198

Modification of glutamic and aspartic acid residues of tissue-type plasminogen activator (t-PA) with 1-ethyl-3(3-dimethyl-aminopropyl)-carbodiimide leads to a decrease in affinity for lysine and fibrin, to a decrease of plasminogen activation activit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4a20802ae0319d44ad08956fbce1e48
https://doi.org/10.1093/protein/4.2.191

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