P377 Impact of moderate-to-severe endoscopic disease criteria on endoscopic response, endoscopic remission, and deep remission in patients receiving ustekinumab or adalimumab in the SEAVUE study

Autor: M Allez, J D Lewis, S B Hanauer, S Danese, P M Irving, C Gasink, T Hoops, J L Izanec, T Ma, E V Loftus, E J Scherl, R Panaccione, W J Sandborn, B E Sands

Publikováno v: Journal of Crohn's and Colitis. 16:i379-i380

Background Entry criteria and outcome measures of Crohn’s disease (CD) clinical trials have evolved. Patients are now required to have active inflammation on screening endoscopy, with some studies requiring moderate-severe SES-CD scores. Recent tri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa7e758d8f8fa42764d6e5cccdf7201e
https://doi.org/10.1093/ecco-jcc/jjab232.504

Modelling Human Gut‐Microbiome Interactions in a 3D Bioelectronic Platform.

Autor: Moysidou, Chrysanthi‐Maria¹ (AUTHOR), van Niekerk, Douglas C.¹ (AUTHOR), Stoeger, Verena¹ (AUTHOR), Pitsalidis, Charalampos^1,2,3 (AUTHOR), Draper, Lorraine A.⁴ (AUTHOR), Withers, Aimee M.¹ (AUTHOR), Hughes, Katherine⁵ (AUTHOR), McCoy, Reece¹ (AUTHOR), Acharya, Rachana¹ (AUTHOR), Hill, Colin⁴ (AUTHOR), Owens, Róisín M.¹ (AUTHOR) rmo37@cam.ac.uk

Publikováno v: Small Science. Jun2024, Vol. 4 Issue 6, p1-17. 17p.

Transforming Growth Factor Beta Promotes Inflammation and Tumorigenesis in Smad4‐Deficient Intestinal Epithelium in a YAP‐Dependent Manner.

Autor: Liu, Liansheng^1,2 (AUTHOR), Wang, Yalong^1,2 (AUTHOR), Yu, Shicheng^1,2 (AUTHOR), Liu, Huidong³ (AUTHOR), Li, Yehua³ (AUTHOR), Hua, Shan^2,4 (AUTHOR), Chen, Ye‐Guang^2,3,5 (AUTHOR) ygchen@tsinghua.edu.cn

Publikováno v: Advanced Science. 8/15/2023, Vol. 10 Issue 23, p1-16. 16p.

A Review of Gut Microbiota‐Derived Metabolites in Tumor Progression and Cancer Therapy.

Autor: Yang, Qiqing^1,2 (AUTHOR), Wang, Bin² (AUTHOR), Zheng, Qinghui¹ (AUTHOR), Li, Heyu² (AUTHOR), Meng, Xuli¹ (AUTHOR) mxlmail@126.com, Zhou, Fangfang³ (AUTHOR) zhoufangfang@suda.edu.cn, Zhang, Long^2,4,5,6 (AUTHOR) L_Zhang@zju.edu.cn

Publikováno v: Advanced Science. 5/26/2023, Vol. 10 Issue 15, p1-27. 27p.

Leveraging Organ-on-Chip Models to Investigate Host-Microbiota Dynamics and Targeted Therapies for Inflammatory Bowel Disease.

Autor: Kaden T; Dynamic42 GmbH, 07745, Jena, Germany.; Institute of Biochemistry II, Center for Sepsis Control and Care, Jena University Hospital, 07747, Jena, Germany., Alonso-Román R; Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute, 07745, Jena, Germany.; Cluster of Excellence Balance of the Microverse, Friedrich Schiller University Jena, 07745, Jena, Germany., Stallhofer J; Department of Internal Medicine IV, Jena University Hospital, 07747, Jena, Germany., Gresnigt MS; Cluster of Excellence Balance of the Microverse, Friedrich Schiller University Jena, 07745, Jena, Germany.; Junior Research Group Adaptive Pathogenicity Strategies, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute, 07745, Jena, Germany., Hube B; Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute, 07745, Jena, Germany.; Cluster of Excellence Balance of the Microverse, Friedrich Schiller University Jena, 07745, Jena, Germany.; Institute of Microbiology, Faculty of Biological Sciences, Friedrich Schiller University, 07743, Jena, Germany., Mosig AS; Institute of Biochemistry II, Center for Sepsis Control and Care, Jena University Hospital, 07747, Jena, Germany.; Cluster of Excellence Balance of the Microverse, Friedrich Schiller University Jena, 07745, Jena, Germany.

Publikováno v: Advanced healthcare materials [Adv Healthc Mater] 2024 Nov 03, pp. e2402756. Date of Electronic Publication: 2024 Nov 03.