Zobrazeno 1 - 10
of 45
pro vyhledávání: '"E J Kanzy"'
Publikováno v:
The Journal of Immunology. 147:4366-4373
Completely humanized antibodies with specificity for the human alpha/beta TCR have been produced by genetic engineering. The L and H chain V region exons encoding the murine mAb BMA 031 CD regions and human EU framework regions were synthesized and r
Publikováno v:
Hybridoma. 10:547-556
According to a recommendation from WHO (World Health Organisation) for prevention of a possible rabies infection, active vaccination has to be combined with application of immunoglobulin to get a fast protective effect. At present, preparations of pu
Publikováno v:
Agents and Actions. 34:161-164
The anti-rat alpha/beta-TCR, MAb-R73 has been investigated as to its disease modifying activity on adjuvant arthritis (AA), on experimental allergic encephalomyelitis (EAE) and on a local graft versus host (GvH) reaction (popliteal lymph nodes = PLN)
Publikováno v:
The Journal of Immunology. 146:928-935
Murine/human chimeric antibodies with specificity for the human TCR-alpha/beta have been produced by genetic engineering. The L and H chain V region exons encoding the murine mAb BMA 031 were isolated and inserted into mammalian expression vectors co
Publikováno v:
Inflammation Research. 44:S194-S196
As has been reported previously, models of chronic graft-versus-host (GvH) and systemic lupus erythematosus (SLE)-like diseases are characterized by high IgE and IgG1 immunoglobulin (Ig) levels in the serum. An IL-4 induced pathological expansion of
Publikováno v:
Agents and Actions. 41:C180-C182
Due to the immunopharmacological profile of soluble recombinant interleukin-4 receptor (IL-4-R) to bind specifically the corresponding ligand Il-4 and there-by to modulate biological activity upon exogenous administration in various autoimmune diseas
Publikováno v:
Behring Institute Mitteilungen. (96)
Autor:
K, Enssle, B, Enders, R, Kurrle, L, Lauffer, H U, Schorlemmer, G, Dickneite, E J, Kanzy, F R, Seiler
Publikováno v:
Behring Institute Mitteilungen. (96)
Publikováno v:
Behring Institute Mitteilungen. (96)
Recombinant soluble forms of transmembrane receptors can be produced in monomeric and dimeric versions. Binding affinity and neutralization potential of these different forms of soluble receptors depend on the quaternary structure of their ligands. M
Publikováno v:
Agents and actions.
Due to the immunopharmacological profile of the recombinant IL-1 receptor (IL-1-R) and its potential to modulate biological activity in various inflammatory autoimmune disease models, we further elucidated its disease modifying activity on the develo