Zobrazeno 1 - 10
of 45
pro vyhledávání: '"E J C G, van den Oord"'
Autor:
William E. Copeland, E J C G van den Oord, Barbara Franke, Mandy Meijer, Karolina A. Aberg, Marieke Klein
Publikováno v:
European Neuropsychopharmacology. 40:S26-S27
Autor:
Andrey A. Shabalin, Mohammad W. Hattab, Robin F. Chan, Shaunna L. Clark, Moji Aghajani, Karolina A. Aberg, Y. Milaneschi, Brian Dean, Min Zhao, E J C G van den Oord, Rick Jansen, Laura K.M. Han, Gaurav Kumar, L. Ying Xie, B.W.J.H. Penninx
Publikováno v:
European Neuropsychopharmacology. 29:S22
Autor:
James J. Crowley, Shaunna L. Clark, Patrick F. Sullivan, Sarah A. Vunck, Robert E. Vann, Joseph L. McClay, E J C G van den Oord, Renan P. Souza, Daniel E. Adkins, Angela M. Batman, Patrick M. Beardsley
Publikováno v:
Genes, Brain and Behavior. 12:780-791
Behavioral sensitization has been widely studied in animal models and is theorized to reflect neural modifications associated with human psychostimulant addiction. While the mesolimbic dopaminergic pathway is known to play a role, the neurochemical m
Autor:
Hans-Jörgen Grabe, Aaron R. Wolen, Henning Tiemeier, Grant W. Montgomery, Martin Preisig, Anjali K. Henders, Yuri Milaneschi, Albertine J. Oldehinkel, Matthew C. Keller, Matthias Nauck, John M. Hettema, Dorret I. Boomsma, Albert Hofman, Brenda W.J.H. Penninx, Nicholas G. Martin, Brion S. Maher, Cornelis L. Mulder, Timothy B. Bigdeli, Zoltán Kutalik, F. V. A. van Oort, Christel M. Middeldorp, Naomi R. Wray, S. V. der Auwera, Saira Saeed Mirza, Michel G. Nivard, Nese Direk, P. J. van der Most, Enrique Castelao, Scott D. Gordon, Catharina A. Hartman, Ayman H. Fanous, Jouke-Jan Hottenga, Takeshi Otowa, Enda M. Byrne, Georg Homuth, Minyoung Lee, A. C. Heath, Sarah E. Medland, Steven H. Aggen, Michele L. Pergadia, Karin Hek, Alexander Teumer, Ilja M. Nolte, E J C G van den Oord, P. A. F. Madden, Daniel E. Adkins, André G. Uitterlinden
Publikováno v:
Molecular Psychiatry, 21(10), 1391-1399. Nature Publishing Group
Otowa, T, Hek, K, Lee, M, Byrne, E M, Mirza, S S, Nivard, M G, Bigdeli, T, Aggen, S H, Adkins, D, Wolen, A, Fanous, A, Keller, M C, Castelao, E, Kutalik, Z, der Auwera, S V, Homuth, G, Nauck, M, Teumer, A, Milaneschi, Y, Hottenga, J-J, Direk, N, Hofman, A, Uitterlinden, A, Mulder, C L, Henders, A K, Medland, S E, Gordon, S, Heath, A C, Madden, P A F, Pergadia, M L, van der Most, P J, Nolte, I M, van Oort, F V A, Hartman, C A, Oldehinkel, A J, Preisig, M, Grabe, H J, Middeldorp, C M, Penninx, B W J H, Boomsma, D, Martin, N G, Montgomery, G, Maher, B S, van den Oord, E J, Wray, N R, Tiemeier, H & Hettema, J M 2016, ' Meta-analysis of genome-wide association studies of anxiety disorders ', Molecular Psychiatry, vol. 21, no. 10, pp. 1391-1399 . https://doi.org/10.1038/mp.2015.197
Otowa, T, Hek, K, Byrne, E M, Mirza, S S, Nivard, M G, Bigdeli, T B, Aggen, S H, Adkins, D E, Wolen, A, Fanous, A, Keller, M C, Castelao, E, Kutalik, Z, van der Auwera, S V, Homuth, G, Nauck, M, Teumer, A, Milaneschi, Y, Hottenga, J J, Direk, N, Hofman, A, Uitterlinden, A G, Mulder, C L, Henders, A K, Medland, S E, Gordon, S, Heath, A C, Madden, P A F, Pergadia, M L, van der Most, P J, Nolte, I M, van Oort, F V A, Hartman, C A, Oldehinkel, A J, Preisig, M, Grabe, H J, Middeldorp, C M, Penninx, B W J H, Boomsma, D I, Martin, N G, Montgomery, G W, Maher, B S, van den Oord, E J, Wray, N R, Tiemeier, H & Hettema, J M 2016, ' Meta-analysis of genome-wide association studies of anxiety disorders ', Molecular Psychiatry, vol. 21, no. 10, pp. 1391-1399 . https://doi.org/10.1038/mp.2015.197
Molecular Psychiatry, 21(10). Nature Publishing Group
Molecular psychiatry
Molecular Psychiatry, vol. 21, no. 10, pp. 1391-1399
Otowa, T, Hek, K, Lee, M, Byrne, E M, Mirza, S S, Nivard, M G, Bigdeli, T, Aggen, S H, Adkins, D, Wolen, A, Fanous, A, Keller, M C, Castelao, E, Kutalik, Z, der Auwera, S V, Homuth, G, Nauck, M, Teumer, A, Milaneschi, Y, Hottenga, J-J, Direk, N, Hofman, A, Uitterlinden, A, Mulder, C L, Henders, A K, Medland, S E, Gordon, S, Heath, A C, Madden, P A F, Pergadia, M L, van der Most, P J, Nolte, I M, van Oort, F V A, Hartman, C A, Oldehinkel, A J, Preisig, M, Grabe, H J, Middeldorp, C M, Penninx, B W J H, Boomsma, D, Martin, N G, Montgomery, G, Maher, B S, van den Oord, E J, Wray, N R, Tiemeier, H & Hettema, J M 2016, ' Meta-analysis of genome-wide association studies of anxiety disorders ', Molecular Psychiatry, vol. 21, no. 10, pp. 1391-1399 . https://doi.org/10.1038/mp.2015.197
Otowa, T, Hek, K, Byrne, E M, Mirza, S S, Nivard, M G, Bigdeli, T B, Aggen, S H, Adkins, D E, Wolen, A, Fanous, A, Keller, M C, Castelao, E, Kutalik, Z, van der Auwera, S V, Homuth, G, Nauck, M, Teumer, A, Milaneschi, Y, Hottenga, J J, Direk, N, Hofman, A, Uitterlinden, A G, Mulder, C L, Henders, A K, Medland, S E, Gordon, S, Heath, A C, Madden, P A F, Pergadia, M L, van der Most, P J, Nolte, I M, van Oort, F V A, Hartman, C A, Oldehinkel, A J, Preisig, M, Grabe, H J, Middeldorp, C M, Penninx, B W J H, Boomsma, D I, Martin, N G, Montgomery, G W, Maher, B S, van den Oord, E J, Wray, N R, Tiemeier, H & Hettema, J M 2016, ' Meta-analysis of genome-wide association studies of anxiety disorders ', Molecular Psychiatry, vol. 21, no. 10, pp. 1391-1399 . https://doi.org/10.1038/mp.2015.197
Molecular Psychiatry, 21(10). Nature Publishing Group
Molecular psychiatry
Molecular Psychiatry, vol. 21, no. 10, pp. 1391-1399
Anxiety disorders (ADs), namely generalized AD, panic disorder and phobias, are common, etiologically complex conditions with a partially genetic basis. Despite differing on diagnostic definitions based on clinical presentation, ADs likely represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::011f115038c1789a067a7ad63e5907ef
https://research.vu.nl/en/publications/a173ee93-9dbe-4005-b8e9-e91151ac20a7
https://research.vu.nl/en/publications/a173ee93-9dbe-4005-b8e9-e91151ac20a7
Autor:
Gonneke Willemsen, Cathryn M. Lewis, Dorret I. Boomsma, Michele L. Pergadia, Peter McGuffin, Brenda W.J.H. Penninx, Douglas Blackwood, Pa Madden, Dixie J. Statham, Nicholas G. Martin, Jouke-Jan Hottenga, Enda M. Byrne, Dale R. Nyholt, Grant W. Montgomery, Patrick F. Sullivan, Stephan Ripke, E. J. C. G. van den Oord, Brian P. McEvoy, Naomi R. Wray, Anjali K. Henders, Donald J. MacIntyre, Sarah E. Medland, Kevin A. McGhee, Jimmy Z. Liu, Jan H. Smit, Ian B. Hickie, Scott D. Gordon, Stuart MacGregor, Alan W Maclean, A. C. Heath, E.J.C. de Geus, Christel M. Middeldorp
Publikováno v:
Molecular Psychiatry, 17(1), 36-48. Nature Publishing Group
Wray, N R, Pergadia, M L, Blackwood, D H, Penninx, B W J H, Gordon, S D, Nyholt, DR, Ripke, S, MacIntyre, D J, McGhee, K A, Maclean, A W, Smit, J H, Hottenga, J J, Willemsen, G, Middeldorp, C M, de Geus, E J C, Lewis, C M, McGuffin, P, Hickie, I B, van den Oord, E J C G, Liu, J Z, Macgregor, S, McEvoy, B P, Byrne, E M, Medland, S E, Statham, D J, Henders, A K, Heath, A C, Montgomery, G W, Martin, N G, Boomsma, D I, Madden, P A F & Sullivan, P F 2012, ' Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned ', Molecular Psychiatry, vol. 17, no. 1, pp. 36-48 . https://doi.org/10.1038/mp.2010.109
Molecular Psychiatry
Wray, N R, Pergadia, M L, Blackwood, D H R, Penninx, B W J H, Gordon, S D, Nyholt, D R, Ripke, S, MacIntyre, D J, McGhee, K A, Maclean, A W, Smit, J H, Hottenga, J J, Willemsen, G, Middeldorp, C M, de Geus, E J C, Lewis, C M, McGuffin, P, Hickie, I B, van den Oord, E J C G, Liu, J Z, Macgregor, S, McEvoy, B P, Byrne, E M, Medland, S E, Statham, D J, Henders, A K, Heath, A C, Montgomery, G W, Martin, N G, Boomsma, D I, Madden, P A F, Sullivan, P F & MacIntyre, D 2012, ' Genome-wide association study of major depressive disorder : new results, meta-analysis, and lessons learned ', Molecular Psychiatry, vol. 17, no. 1, pp. 36-48 . https://doi.org/10.1038/mp.2010.109
Wray, N R, Pergadia, M L, Blackwood, D H, Penninx, B W J H, Gordon, S D, Nyholt, DR, Ripke, S, MacIntyre, D J, McGhee, K A, Maclean, A W, Smit, J H, Hottenga, J J, Willemsen, G, Middeldorp, C M, de Geus, E J C, Lewis, C M, McGuffin, P, Hickie, I B, van den Oord, E J C G, Liu, J Z, Macgregor, S, McEvoy, B P, Byrne, E M, Medland, S E, Statham, D J, Henders, A K, Heath, A C, Montgomery, G W, Martin, N G, Boomsma, D I, Madden, P A F & Sullivan, P F 2012, ' Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned ', Molecular Psychiatry, vol. 17, no. 1, pp. 36-48 . https://doi.org/10.1038/mp.2010.109
Molecular Psychiatry
Wray, N R, Pergadia, M L, Blackwood, D H R, Penninx, B W J H, Gordon, S D, Nyholt, D R, Ripke, S, MacIntyre, D J, McGhee, K A, Maclean, A W, Smit, J H, Hottenga, J J, Willemsen, G, Middeldorp, C M, de Geus, E J C, Lewis, C M, McGuffin, P, Hickie, I B, van den Oord, E J C G, Liu, J Z, Macgregor, S, McEvoy, B P, Byrne, E M, Medland, S E, Statham, D J, Henders, A K, Heath, A C, Montgomery, G W, Martin, N G, Boomsma, D I, Madden, P A F, Sullivan, P F & MacIntyre, D 2012, ' Genome-wide association study of major depressive disorder : new results, meta-analysis, and lessons learned ', Molecular Psychiatry, vol. 17, no. 1, pp. 36-48 . https://doi.org/10.1038/mp.2010.109
Major depressive disorder (MDD) is a common complex disorder with a partly genetic etiology. We conducted a genome-wide association study of the MDD2000þ sample (2431 cases, 3673 screened controls and >1M imputed single-nucleotide polymorphisms (SNP
Publikováno v:
Molecular Psychiatry
Molecular psychiatry
Molecular psychiatry
The lack of reliable measures of alcohol intake is a major obstacle to the diagnosis and treatment of alcohol-related diseases. Epigenetic modifications such as DNA methylation may provide novel biomarkers of alcohol use. To examine this possibility,
Autor:
Karolina A. Aberg, E J C G van den Oord, Peilin Jia, Zhongming Zhao, Patrick F. Sullivan, Joseph L. McClay, Yunlong Liu, Daniel E. Adkins, T S Stroup, J A Lieberman, Diana O. Perkins, József Bukszár
Publikováno v:
The pharmacogenomics journal
QT prolongation is associated with increased risk of cardiac arrhythmias. Identifying the genetic variants that mediate antipsychotic-induced prolongation may help to minimize this risk, which might prevent the removal of efficacious drugs from the m
Autor:
Sarah E. Bergen, Kenneth S. Kendler, Francis A. O'Neill, Ayman H. Fanous, E J C G van den Oord, Brion S. Maher, Brien P. Riley, Zhongming Zhao, Dawn L. Thiselton, Tim B. Bigdeli, Declan Walsh, Richard Amdur, Brandon Wormley
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :663-674
SNAP25 occurs on chromosome 20p12.2, which has been linked to schizophrenia in some samples, and recently linked to latent classes of psychotic illness in our sample. SNAP25 is crucial to synaptic functioning, may be involved in axonal growth and den
Autor:
Xiangning Chen, Kenneth S. Kendler, E J C G van den Oord, John M. Hettema, Seon-Sook An, Michael C. Neale
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :661-666
The serotonin neurotransmitter system in general, and the serotonin 1A receptor in particular, has been broadly implicated in the pathophysiology of mood and anxiety disorders, although the results of genetic association studies have been mixed. In t
Autor:
Diana O. Perkins, Danyu Lin, Fei Zou, Jung-Ying Tzeng, A. M. Downing, Patrick F. Sullivan, E J C G van den Oord, T. S. Stroup, Seunggeun Lee, J A Lieberman, W. Liu, S. L. Close, Fred A. Wright, Michael J. Wagner
Publikováno v:
Molecular Psychiatry. 13:570-584
Little is known for certain about the genetics of schizophrenia. The advent of genomewide association has been widely anticipated as a promising means to identify reproducible DNA sequence variation associated with this important and debilitating dis