Zobrazeno 1 - 8
of 8
pro vyhledávání: '"E J, Woolf"'
Publikováno v:
Chromatographia. 55:S137-S144
Methods for the determination of a novel, ascomycin-based macrolide immunosuppressant in human plasma and whole blood are described. Following protein precipitation, the analyte and an internal standard were extracted from each matrix using solid pha
Publikováno v:
Chromatographia. 39:79-84
A method for the determination of L-697, 661, a human immunodeficiency virus type 1 reverse transcriptase inhibitor, and its 6-hydroxy metabolite in plasma is described. Following analyte isolation via solid phase extraction, samples are analyzed by
Autor:
S A, Merschman, M J, Rose, G E S, Pearce, E J, Woolf, B H, Schaefer, A C, Huber, D G, Musson, K J, Perry, D J, Rush, R J, Varsolona, B K, Matuszewski
Publikováno v:
Die Pharmazie. 60(5)
The solubility, in human urine, of the major hydroxylated metabolite (M1) of an experimental cognition enhancer was characterized through a series of in vitro experiments in an effort to estimate the probability of crystalluria occurring following or
Publikováno v:
Die Pharmazie. 59(12)
Etoricoxib is a potent and novel selective inhibitor of cyclooxygenase-2 (COX-2) which has been developed for the treatment of osteoarthritis, rheumatoid arthritis and several other inflammatory conditions. To support clinical pharmacokinetics studie
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 24(12)
Indinavir, N-[2(R)-hydroxy-1(S)-indanyl]-5-[2(S)-tertiary- butylaminocarbonyl-4-(3-pyridylmethyl)piperazino]-4(S)- hydroxy-2(R)-phenylmethylpentanamide (L-735,524,MK-639, ayl-4- Crixivan), is a potent and specific inhibitor of the HIV-1(3 protease fo
Autor:
E J, Woolf, B K, Matuszewski
Publikováno v:
Pharmaceutical research. 10(1)
A method for the determination of a 2-pyridinone-based specific HIV-1 reverse transcriptase inhibitor in human plasma is described. Plasma samples are extracted using phenyl solid phase extraction columns. The extract is analyzed via HPLC using a col
Autor:
J Woolf E; Merck & Co., PPDM Regulated PK Bioanalytics, WP 75B-300, West Point, PA 19486, USA.
Publikováno v:
Bioanalysis [Bioanalysis] 2019 Sep; Vol. 11 (18), pp. 1679-1684. Date of Electronic Publication: 2019 Sep 26.
Autor:
J Woolf E; Merck & Co., Inc., Pharmacokinetics, Pharmacodynamics & Drug Metabolism, Regulated Bioanalysis, 770 Sumneytown Pike, WP75B-300, West Point, PA 19486, USA.
Publikováno v:
Bioanalysis [Bioanalysis] 2019 Aug; Vol. 11 (15), pp. 1387-1388.