Zobrazeno 1 - 10 of 22 pro vyhledávání: '"E J, Shannon"'
1
Effects of Thalidomide on IntracellularMycobacterium lepraein Normal and Activated Macrophages
Autor: E. J. Shannon, A. Tadesse
Publikováno v: Clinical and Vaccine Immunology. 12:130-134
Thalidomide is an effective drug for the treatment of erythema nodosum leprosum (ENL). ENL is an inflammatory reaction that may occur in multibacillary leprosy patients. Its cause(s) as well as the mechanism of thalidomide in arresting this condition
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007ead1274e1cdfda985a0161cb4f738
https://doi.org/10.1128/cdli.12.1.130-134.2005
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2
Early detection of rifampin in human nerve tissue after an oral dose of 600 milligrams
Autor: R Kazen, D Frommel, E J Shannon, Guebre-Xabier M, Z Kebret
Publikováno v: Antimicrobial Agents and Chemotherapy. 39:1866-1870
Rifampin in picogram quantities inhibited the ability of Mycobacterium bovis 44 BCG P3 to release 14CO2 from the oxidation of [14C]palmitic acid. By using these mycobacteria in a bioassay, samples of serum and posterior tibial nerve were assayed for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2295258939c2e09de613fa1e8856813e
https://doi.org/10.1128/aac.39.8.1866
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4
Analysis of T-cell and B-cell responses to recombinant M. leprae antigens in leprosy patients and in healthy contacts: significant T-cell responses to antigens in M. leprae nonresponders
Autor: J E, Thole, A A, Janson, A, Kifle, R C, Howe, K, McLean, A, Nurilygn, E, Filley, E J, Shannon, G J, Bulla, J, Hermans
Publikováno v: International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 63(3)
The recognition of a panel of recombinant Mycobacterium leprae antigens by T cells and B cells from 29 borderline tuberculoid/tuberculoid (BT/TT) and 18 lepromatous leprosy (LL) patients and from 21 healthy controls (HC) in leprosy-endemic regions of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e86023b00985673489dbe2b399353cf1
https://pubmed.ncbi.nlm.nih.gov/7594920
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5
Titration of numbers of human-derived Mycobacterium leprae required to progressively oxidize 14C-palmitic acid and release 14CO2
Autor: E J, Shannon, D, Frommel, M, Guebre-Xabier, H S, Haile-Mariam
Publikováno v: Leprosy review. 65(2)
Mycobacterium leprae was isolated from skin-punch biopsies of 2 untreated lepromatous leprosy patients. The bacteria were enumerated, diluted 10-fold and cultured in Middlebrook 7H9 medium supplemented with albumin, dextrose, catalase and 14C-palmiti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0b4509a164616b7a612eb9418df03af9
https://pubmed.ncbi.nlm.nih.gov/7968182
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6
Competency of human-derived Mycobacterium leprae to use palmitic acid in the synthesis of phenolic glycolipid-I and phthiocerol dimycocerosate and to release CO2 in axenic culture
Autor: E J, Shannon, E B, Harris, H S, Haile-Mariam, M, Guebre-Xavier, D, Frommel
Publikováno v: Leprosy review. 63(2)
Insufficient numbers of viable Mycobacterium leprae have hampered metabolic studies using human-derived M. leprae. In this study, sufficient numbers of M. leprae were obtained from an untreated lepromatous patient to titrate the effects of pH on the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a3ef4e4af307fef1421f58ec3870a72f
https://pubmed.ncbi.nlm.nih.gov/1640777
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7
Thalidomide's effectiveness in erythema nodosum leprosum is associated with a decrease in CD4+ cells in the peripheral blood
Autor: Genet Tasesse, E. J. Shannon, H. S. Haile-Mariam, Mestawat Ejigu, Tebebe Yemane Berhan
Publikováno v: Leprosy Review. 63
Thalidomide is well documented as being an effective drug in the treatment of erythema nodosum leprosum (ENL). The mechanism of action of thalidomide in ENL as well as the pathogenesis of ENL are yet to be fully determined. Lepromatous leprosy patien
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62d4787f3fc2900c9521262f1be082a
https://doi.org/10.5935/0305-7518.19920002
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8
The evolution of antibody response in armadillos inoculated with Mycobacterium leprae
Autor: A. R. Vadiee, E. Harris, E. J. Shannon
Publikováno v: Leprosy review. 61(3)
Plasma from 30 armadillos (Dasypus novemcinctus) was collected prior to inoculation and at approximately 3-month intervals for a period of 1-3 years. These animals were inoculated intravenously with 6.1 x 10(8) +/- 2 x 10(8) (x +/- SD) armadillo-deri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55998a7e8fac210124796d684c0f4d29
https://pubmed.ncbi.nlm.nih.gov/2215054
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9
Confirmation of a false-positive result associated with a competition inhibition assay used for detecting antibodies to a protein epitope of Mycobacterium leprae
Autor: T P Gillis, E J Shannon, A R Vadiee
Publikováno v: Clinical and experimental immunology. 79(3)
SUMMARY A competitive antibody-binding assay (CABA) was developed to detect antibodies in infected armadillos and leprosy patients which compete with an M. leprae-specific125I monoclonal antibody IIIE9 for the species-specific M. leprae-IIIE9 epitope
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2179846056a0e41a5a93ec8688fb49
https://pubmed.ncbi.nlm.nih.gov/1690616
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10
Evaluation of the Origin of Mycobacterium Leprae Infections in the Wild Armadillo, Dasypus Novemcinctus
Autor: Truman Rw, R C Hastings, E J Shannon, Martin Hugh-Jones, A Wolff, H V Hagstad
Publikováno v: The American Journal of Tropical Medicine and Hygiene. 35:588-593
An enzyme-linked immunosorbent assay (ELISA) using the phenolic glycolipid-1 (PGL-1) antigen of Mycobacterium leprae and cross-reactive antisera specific for human IgM was developed to detect IgM antibodies to M. leprae in the nine-banded armadillo (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d57862d317e7544bde235613a0a7a3cf
https://doi.org/10.4269/ajtmh.1986.35.588
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