Zobrazeno 1 - 10
of 67
pro vyhledávání: '"E J, Neer"'
Publikováno v:
The Journal of biological chemistry. 276(4)
Phosphatidylinositol-specific phospholipase C-betas (PLC-betas) are the only PLC isoforms that are regulated by G protein subunits. To further understand the regulation of PLC-beta(2) by G proteins and the functional roles of PLC-beta(2) structural d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33a26810c3c7c3e25b1bf57da4446d2e
https://pubmed.ncbi.nlm.nih.gov/11044443
https://pubmed.ncbi.nlm.nih.gov/11044443
Publikováno v:
Journal of neuroscience research. 54(2)
Heterotrimeric G-proteins, composed of alpha and betagamma subunits, transmit signals from cell-surface receptors to cellular effectors and ion channels. Cellular responses to receptor agonists depend on not only the type and amount of G-protein subu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d9c63d8194bf2c270c919d80069c229c
https://pubmed.ncbi.nlm.nih.gov/9788285
https://pubmed.ncbi.nlm.nih.gov/9788285
Autor:
M P, Panchenko, K, Saxena, Y, Li, S, Charnecki, P M, Sternweis, T F, Smith, A G, Gilman, T, Kozasa, E J, Neer
Publikováno v:
The Journal of biological chemistry. 273(43)
The betagamma subunits of the heterotrimeric GTP-binding proteins (G proteins) that couple heptahelical, plasma membrane-bound receptors to intracellular effector enzymes or ion channels directly regulate several types of effectors, including phospho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1f59f378e54ab7e490784add29627f7
https://pubmed.ncbi.nlm.nih.gov/9774453
https://pubmed.ncbi.nlm.nih.gov/9774453
Publikováno v:
The Journal of biological chemistry. 273(15)
The beta subunit of the heterotrimeric G proteins that transduce signals across the plasma membrane is made up of an amino-terminal alpha-helical segment followed by seven repeating units called WD (Trp-Asp) repeats that occur in about 140 different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7404863080971ac2458b6a1074aede53
https://pubmed.ncbi.nlm.nih.gov/9535892
https://pubmed.ncbi.nlm.nih.gov/9535892
Autor:
D E, Clapham, E J, Neer
Publikováno v:
Annual review of pharmacology and toxicology. 37
Guanine nucleotide binding (G) proteins relay extracellular signals encoded in light, small molecules, peptides, and proteins to activate or inhibit intracellular enzymes and ion channels. The larger G proteins, made up of G alpha beta gamma heterotr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f65da3512a1a48553ef76971a3675c13
https://pubmed.ncbi.nlm.nih.gov/9131251
https://pubmed.ncbi.nlm.nih.gov/9131251
Publikováno v:
The Journal of biological chemistry. 271(1)
Heterotrimeric guanine nucleotide binding proteins (G proteins) are made up of alpha, beta, and gamma subunits, the last two forming a very tight complex. Stimulation of cell surface receptors promotes dissociation of alpha from the beta gamma dimer,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41e908d2c19ffb17401b467fe84d8deb
https://pubmed.ncbi.nlm.nih.gov/8550614
https://pubmed.ncbi.nlm.nih.gov/8550614
Publikováno v:
The Journal of biological chemistry. 270(26)
Guanine nucleotide-binding protein beta and gamma subunits form a tightly bound complex that can only be separated by denaturation. Assembly of beta and gamma subunits is a complicated process. The beta 1 and gamma 2 subunits can be synthesized in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::23b8e0c7e5caf8d266d9aacb0116cf19
https://pubmed.ncbi.nlm.nih.gov/7541050
https://pubmed.ncbi.nlm.nih.gov/7541050
Publikováno v:
The Journal of biological chemistry. 269(44)
Many responses of cells to external signals require activation of the heterotrimeric G proteins. These responses depend on the type and amount of G proteins that are expressed. Each cell has a characteristic complement of G protein subunits. For exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b8660e05166773e85071506d9cacb5f
https://pubmed.ncbi.nlm.nih.gov/7961675
https://pubmed.ncbi.nlm.nih.gov/7961675
Autor:
D J, Spring, E J, Neer
Publikováno v:
The Journal of biological chemistry. 269(36)
Heterotrimeric guanine nucleotide-binding proteins are important signaling molecules composed of an alpha, beta, and gamma subunit. The beta subunits must form dimers with gamma subunits to function. Several subtypes of beta and gamma have been ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9251a644cb021461bcea68eeb0134608
https://pubmed.ncbi.nlm.nih.gov/8077239
https://pubmed.ncbi.nlm.nih.gov/8077239
Publikováno v:
Journal of neuroscience research. 38(2)
The developmental pattern of expression of the G protein alpha o subunit and GAP43 were compared by immunohistochemical staining of mouse embryos. Staining for alpha o and GAP43 was identical and detected throughout the developing nervous system, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69bf52439636404d6a99689f16aab365
https://pubmed.ncbi.nlm.nih.gov/8078103
https://pubmed.ncbi.nlm.nih.gov/8078103