Zobrazeno 1 - 10
of 14
pro vyhledávání: '"E J, Lehning"'
Publikováno v:
Neurotoxicology. 24(1)
Previous studies of acrylamide (ACR) neuropathy in rat PNS [Toxicol. Appl. Pharmacol. (1998) 151:211-221] and in spinal cord, brainstem and cerebellum [NeuroToxicology (2002a) 23:397-414; NeuroToxicology (2002b) 23:415-429] have suggested that axon d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6cb2528fac9d07cd8e3263de7d1f5e0a
https://pubmed.ncbi.nlm.nih.gov/12564388
https://pubmed.ncbi.nlm.nih.gov/12564388
Publikováno v:
Neurotoxicology. 23(3)
Based on evidence from morphometric studies of PNS, we suggested that acrylamide (ACR)-induced distal axon degeneration was a secondary effect related to duration of exposure [Toxicol. Appl. Pharmacol. 151 (1998) 211]. To test this hypothesis in CNS,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d9bf4ec0c96ffd21b9a412f7956ed2a
https://pubmed.ncbi.nlm.nih.gov/12387366
https://pubmed.ncbi.nlm.nih.gov/12387366
Publikováno v:
Neurotoxicology. 23(3)
Previous studies of acrylamide (ACR) neuropathy in rat PNS [Toxicol. Appl. Pharmacol. 151 (1998) 211] and cerebellum [NeuroToxicology 23 (2002) 397] have suggested that axon degeneration was not a primary effect and was, therefore, of unclear neuroto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e2a9265bf0137b3091808ed0b489b1db
https://pubmed.ncbi.nlm.nih.gov/12387367
https://pubmed.ncbi.nlm.nih.gov/12387367
Publikováno v:
Neurotoxicology. 22(2)
Evidence suggests the morphologic hallmark of gamma-diketone neuropathy is axon atrophy and that this effect is associated with reduced neurofilament (NF) subunit protein content (Toxicol Appl Pharmacol 2000;165:141-7). To investigate the mechanism o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1333dd930b2d40f0a2ad3402de2cdcc0
https://pubmed.ncbi.nlm.nih.gov/11405253
https://pubmed.ncbi.nlm.nih.gov/11405253
Publikováno v:
Toxicology and applied pharmacology. 165(2)
Quantitative morphometric analysis was used to characterize expression of myelinated axon swelling and atrophy in rat peripheral nerve during 2,5-hexanedione (HD) intoxication. HD was administered by gavage according to different daily dosing regimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d7d2d0b3c8d9ee9e48484c1c19c106a
https://pubmed.ncbi.nlm.nih.gov/10828208
https://pubmed.ncbi.nlm.nih.gov/10828208
Publikováno v:
Toxicology and applied pharmacology. 165(2)
Quantitative morphometric analyses have demonstrated that axon atrophy is the primary neuropathic alteration in peripheral nerve of 2,5-hexanedione (HD)-intoxicated rats (Lehning et al., Toxicol. Appl. Pharmacol. 165, 127-140, 2000). Research suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5817abac8b69cd89b134f5ecae1cc99b
https://pubmed.ncbi.nlm.nih.gov/10828209
https://pubmed.ncbi.nlm.nih.gov/10828209
Publikováno v:
Journal of the peripheral nervous system : JPNS. 2(2)
Decreased axolemmal Na+/K(+)-ATPase activity has been considered as a possible mechanism for peripheral nerve axon damage induced by acrylamide (ACR) or 2,5-hexanedione (HD). Reduced activity of this enzyme is also presumed to be the basis of periphe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48a255f1fdf48b5ad7b004fe6651491b
https://pubmed.ncbi.nlm.nih.gov/10959230
https://pubmed.ncbi.nlm.nih.gov/10959230
Autor:
R M, LoPachin, E J, Lehning
Publikováno v:
Neurotoxicology. 18(1)
Traditionally, gamma-diketone neuropathy is classified as a distal axonopathy and has been characterized by giant axonal swellings in CNS and PNS tissues. These swellings contain neurofilamentous masses and are associated with thinning and retraction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::73aaeac733320c8dff35b54595adecad
https://pubmed.ncbi.nlm.nih.gov/9215985
https://pubmed.ncbi.nlm.nih.gov/9215985
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 29(1)
This study compared the neurotoxic effects of triphenyl phosphite (TPP) in the rat with those seen after exposure to diisopropylphosphorofluoridate (DFP), a compound known to produce organophosphorus-induced delayed neurotoxicity (OPIDN). Animals rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81db765ff7d71f8449579d3e6031057f
https://pubmed.ncbi.nlm.nih.gov/8838646
https://pubmed.ncbi.nlm.nih.gov/8838646
Publikováno v:
Neurotoxicology. 16(1)
The ameliorative effect(s) of exogenous gangliosides on the development of organophosphorus ester-induced delayed neurotoxicity (OPIDN) suggests that administration of an organophosphorus delayed neurotoxicant could alter the endogenous ganglioside c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8005dcbf7d5150a5f1ecf49533f9c25
https://pubmed.ncbi.nlm.nih.gov/7603645
https://pubmed.ncbi.nlm.nih.gov/7603645