Zobrazeno 1 - 10 of 62 pro vyhledávání: '"E J, Jenkinson"'
1
Inhibition of Histone Deacetylase 6 Reveals a Potent Immunosuppressant Effect in Models of Transplantation
Autor: Andrew R. Ready, E. J. Jenkinson, Mark T. Drayson, Mark Cobbold, Jonathan D. Ellis, Nick G. Inston, Desley Neil, Peter Hampson, Stephen J. Shuttleworth
Publikováno v: Transplantation. 100:1667-1674
BACKGROUND Current transplant immunosuppression regimens have numerous limitations. Recent evidence suggests histone deacetylase inhibitors (HDACis) may represent a class of drug with immunosuppressive properties. This study compares cyclosporin A (C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c62b65311556a5d45244941b4811cf3
https://doi.org/10.1097/tp.0000000000001208
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3
Factors Regulating Stem Cell Recruitment to the Fetal Thymus
Autor: B. Wilkinson, J. J. T. Owen, E. J. Jenkinson
Publikováno v: The Journal of Immunology. 162:3873-3881
Colonization of the thymic rudiment during development is initiated before vascularization so that hemopoietic precursors must leave the pharyngeal vessels and migrate through the perithymic mesenchyme to reach the thymus, suggesting that they may be
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b4c85924d8e109727410169d342dd406
https://doi.org/10.4049/jimmunol.162.7.3873
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4
Stimulation of thymocytes before and after positive selection results in the induction of different NF-kappa B/Rel protein complexes
Autor: N C Moore, J Girdlestone, G Anderson, J J Owen, E J Jenkinson
Publikováno v: The Journal of Immunology. 155:4653-4660
Positive selection triggers the differentiation of immature CD4+8+TCRlow thymocytes into TCRhigh single-positive CD4+ or CD8+ cells and is associated with major changes in gene expression. However, little is known about the DNA binding factors contro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de1099c1ee278f8db1dfd6c3bc5efd84
https://doi.org/10.4049/jimmunol.155.10.4653
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6
Notch ligand-bearing thymic epithelial cells initiate and sustain Notch signaling in thymocytes independently of T cell receptor signaling
Autor: G, Anderson, J, Pongracz, S, Parnell, E J, Jenkinson
Publikováno v: European journal of immunology. 31(11)
Thymic epithelial cells are specialized to play essential roles at multiple stages of T cell development in the thymus, yet the molecular basis of this specialization is largely unknown. Recently, the Notch family of transmembrane proteins has been i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6930b65f02441d0685f7992616ebb7e1
https://pubmed.ncbi.nlm.nih.gov/11745352
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7
Studies on the role of IL-7 presentation by mesenchymal fibroblasts during early thymocyte development
Autor: C M, Banwell, K M, Partington, E J, Jenkinson, G, Anderson
Publikováno v: European journal of immunology. 30(8)
T cell precursor development depends upon poorly defined interactions between thymocyte precursors and stromal cells involving cell surface molecules, extracellular matrix (ECM) components and soluble growth factors. To determine whether presentation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7d53e3de8ecdd1bb8a3c9d6955c33227
https://pubmed.ncbi.nlm.nih.gov/10940902
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9
RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse
Autor: M, Heino, P, Peterson, N, Sillanpää, S, Guérin, L, Wu, G, Anderson, H S, Scott, S E, Antonarakis, J, Kudoh, N, Shimizu, E J, Jenkinson, P, Naquet, K J, Krohn
Publikováno v: European Journal of Immunology, Vol. 30, No 7 (2000) pp. 1884-1893
Mutations in the putative transcription factor autoimmune regulator (AIRE) gene are responsible for autoimmune polyendocrinopathy-candidiosis-ectodermal dystrophy (APECED; OMIM#240300), a monogenic recessively inherited disease characterized by destr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4592cc3f86d77026a824dc077913e890
https://archive-ouverte.unige.ch/unige:8799
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10
Factors regulating stem cell recruitment to the fetal thymus
Autor: B, Wilkinson, J J, Owen, E J, Jenkinson
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 162(7)
Colonization of the thymic rudiment during development is initiated before vascularization so that hemopoietic precursors must leave the pharyngeal vessels and migrate through the perithymic mesenchyme to reach the thymus, suggesting that they may be
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f71374c90317bfde363a97453ba12bde
https://pubmed.ncbi.nlm.nih.gov/10201905
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