Zobrazeno 1 - 10
of 132
pro vyhledávání: '"E J, Ehrhart"'
Autor:
Shukmei Wong, E J Ehrhart, Samuel Stewart, Victoria Zismann, Jacob Cawley, Rebecca Halperin, Natalia Briones, Keith Richter, Karthigayini Sivaprakasam, Nieves Perdigones, Tania Contente-Cuomo, Salvatore Facista, Jeffrey M Trent, Muhammed Murtaza, Chand Khanna, William P D Hendricks
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0264986 (2022)
Cancer genomic heterogeneity presents significant challenges for understanding oncogenic processes and for cancer's clinical management. Variation in driver mutation frequency between patients with the same tumor type as well as within an individual
Externí odkaz:
https://doaj.org/article/62e231b6cdc64d4faee96910a1df5788
Autor:
E. J. Ehrhart, Shukmei Wong, Keith Richter, Victoria Zismann, Carolyn Grimes, William Hendricks, Chand Khanna
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 33, Iss 3, Pp 1392-1402 (2019)
Abstract Background Polymerase chain reaction for antigen receptor rearrangement (PARR) is a molecular diagnostic tool used for discrimination of lymphoid malignancies in dogs from benign processes. Assay variations have been described and are commer
Externí odkaz:
https://doaj.org/article/7fec2d0053a24d0fbfd8f04f7434a04b
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239223 (2020)
Brachycephalic airway syndrome (BAS) is a well-established cause of respiratory distress in dogs. BAS without surgical correction results in eventual laryngeal collapse. Arytenoid lateralization has been used to treat severe laryngeal collapse with s
Externí odkaz:
https://doaj.org/article/afa59966f34745d7ba092efd81f1473e
Autor:
Keagan P. Collins, Sunetra Das, Daniel L. Gustafson, Kristen M. Weishaar, Dawn L. Duval, E. J. Ehrhart, Douglas H. Thamm, Jared S. Fowles
Publikováno v:
Cancer Chemotherapy and Pharmacology. 88:699-712
This study is a prospective clinical trial in dogs with osteosarcoma testing a gene expression model (GEM) predicting the chemosensitivity of tumors to carboplatin (CARBO) or doxorubicin (DOX) developed using the COXEN method. Sixty dogs with appendi
Publikováno v:
Veterinary Ophthalmology. 24:354-360
Objective To demonstrate the existence of lymphatics in the canine anterior uvea using lymphatic-specific markers Lyve-1, Prox-1, and podoplanin, the endothelial cell marker CD31, and basement membrane matrix marker collagen IV. Design Prospective St
Publikováno v:
Journal of the American Animal Hospital Association. 57:139-143
A 7 yr old female spayed Chihuahua-terrier mix was presented for a progressive dry, hacking cough over 9 mo, with dyspnea aggravated by eating and drinking. Computed tomography of the skull revealed a large mineral attenuating mass associated with th
Autor:
J. B. Charles, Lauren N Alfino, Kathryn Cronise, Daniel P. Regan, Kai C Wilczewski-Shirai, E. J. Ehrhart, Dawn L. Duval, Kristina E. Glapa, Jonathan Coy
Publikováno v:
Vet Pathol
Periostin is a matricellular protein important in regulating bone, tooth, and cardiac development. In pathologic conditions, periostin drives allergic and fibrotic inflammatory diseases and is also overexpressed in certain cancers. Periostin signalin
Autor:
Laine E. Feller, Aaron Sargeant, E. J. Ehrhart, Bethany Balmer, Keith Nelson, Jennifer Lamoureux
Publikováno v:
Toxicologic Pathology. :019262332211483
Göttingen minipigs are increasingly used as an alternative large animal model in nonclinical toxicology studies, and proliferative lesions in this species are rare. Here, we report four cases of cardiac rhabdomyoma in Göttingen minipigs, an inciden
Autor:
Ryan C Curtis, James T Custis, Nicole P Ehrhart, E J Ehrhart, Keith W Condon, Sara E Gookin, Seth W Donahue
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158005 (2016)
Clinical studies using definitive-intent stereotactic radiation therapy (SRT) for the local treatment of canine osteosarcoma (OSA) have shown canine patients achieving similar median survival times as the current standard of care (amputation and adju
Externí odkaz:
https://doaj.org/article/8dbdff557e79458ab91a42b70841e926
Autor:
Corey Saba, Melissa Paoloni, Christina Mazcko, William Kisseberth, Jenna H Burton, Annette Smith, Heather Wilson-Robles, Sara Allstadt, David Vail, Carolyn Henry, Susan Lana, E J Ehrhart, Brad Charles, Michael Kent, Jessica Lawrence, Kristine Burgess, Antonella Borgatti, Steve Suter, Paul Woods, Ira Gordon, Patricia Vrignaud, Chand Khanna, Amy K LeBlanc
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149194 (2016)
Development of iniparib as an anti-cancer agent was hindered in part by lingering questions regarding its mechanism of action, the activity of its metabolites, and their potential accumulation in tumors. Due to strong similarities in metabolism of in
Externí odkaz:
https://doaj.org/article/28b7c7f29ad74fe5a2d3cf9ed5449099