Výsledky vyhledávání - "E J, Derbyshire"

The health benefits of whole grains and fibre: A review of published evidence (2007–2012)

Autor: E. J. Derbyshire, C. H. S. Ruxton

Publikováno v: Proceedings of the Nutrition Society. 74

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::07e8801ad0e3a9de5d0bb4c8b9466fc7
https://doi.org/10.1017/s0029665115001627

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Compositionally heterogeneous podiform chromitite in the Shetland Ophiolite Complex (Scotland): implications for chromitite petrogenesis and late stage alteration in the upper mantle portion of a supra-subduction zone ophiolite

Autor: Ralf Gertisser, Davide Lenaz, Brian O'Driscoll, Andreas Kronz, E. J. Derbyshire

The mantle sequence of the ~ 492 Ma Shetland Ophiolite Complex (SOC; Scotland) contains abundant compositionally heterogeneous podiform chromitite bodies enclosed in elongate dunite lenses in the vicinity of the petrological Moho. Chromitite petrogen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be6792839f50e3183471274de986e0b3
http://hdl.handle.net/11368/2630635

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Potent cytotoxic action of the immunotoxin SWA11-ricin A chain against human small cell lung cancer cell lines

Autor: Rolf A. Stahel, E. J. Wawrzynczak, R. V. Henry, E. J. Derbyshire

Publikováno v: British Journal of Cancer

The cytotoxic activity profile of an immunotoxin, SWA11-ricin A chain, recognising a cell-surface antigen associated with human small cell lung cancer (SCLC), was examined in detail using a panel of SCLC, non-SCLC and non lung tumour cell lines in ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1fd0f566b8749564699d0f373934602
https://doi.org/10.1038/bjc.1992.294

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Selective cytotoxic effects of a ricin A chain immunotoxin made with the monoclonal antibody SWA11 recognising a human small cell lung cancer antigen

Autor: G. D. Parnell, E. J. Derbyshire, A Smith, Rolf A. Stahel, Robert Waibel, E. J. Wawrzynczak, R. V. Henry

Publikováno v: British Journal of Cancer

The potential of mouse monoclonal antibodies for recognising different antigens associated with human small cell lung cancer (SCLC) to form active immunotoxins was assessed by an indirect in vitro screening assay. The screening agent used was a conju

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5de215252a56e89dcdef2d055a50a30
https://doi.org/10.1038/bjc.1990.308

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Up-regulation of endoglin on vascular endothelial cells in human solid tumors: implications for diagnosis and therapy

Autor: F J, Burrows, E J, Derbyshire, P L, Tazzari, P, Amlot, A F, Gazdar, S W, King, M, Letarte, E S, Vitetta, P E, Thorpe

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 1(12)

We have characterized a murine IgM monoclonal antibody, TEC-11, that recognizes endoglin and may be suitable for targeting cytotoxic agents to human tumor vasculature. TEC-11 strongly stains endothelial cells in a broad range of solid human tumors wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fc141178d5c5a51ef34e1593b08455a2
https://pubmed.ncbi.nlm.nih.gov/9815965

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Heparin-steroid conjugates: new angiogenesis inhibitors with antitumor activity in mice

Autor: P E, Thorpe, E J, Derbyshire, S P, Andrade, N, Press, P P, Knowles, S, King, G J, Watson, Y C, Yang, M, Rao-Betté

Publikováno v: Cancer research. 53(13)

Inhibitors of angiogenesis hold potential in the treatment of cancer and other diseases where the disease is caused or maintained by the inappropriate growth of blood vessels. In the present study, a novel inhibitor of angiogenesis was synthesized by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d1255bd2bc539e3c77e8ac193fc9b104
https://pubmed.ncbi.nlm.nih.gov/7686447

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Potentiation of a weakly active ricin A chain immunotoxin recognizing the neural cell adhesion molecule

Autor: Rolf A. Stahel, E. J. Wawrzynczak, E. J. Derbyshire

Publikováno v: Clinical and experimental immunology. 89(3)

SUMMARY A ricin A chain immunotoxin, SEN36-ricin A chain, directed against the neural cell adhesion molecule (N-CAM) had no selective cytotoxic activity against three different small cell lung cancer (SCLC) cell lines in tissue culture despite expres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::febdf13cafd5f55d3216107c8ca365b1
https://pubmed.ncbi.nlm.nih.gov/1325302

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Cytotoxic activity of ricin A chain immunotoxins recognising cluster 1, w4 and 5A antigens associated with human small cell lung cancer

Autor: E J, Wawrzynczak, E J, Derbyshire, R V, Henry, G D, Parnell, A, Smith, R, Waibel, R A, Stahel

Publikováno v: The British journal of cancer. Supplement. 14

The potential of mouse monoclonal antibodies raised against the human small cell lung cancer (SCLC) cell line SW2 to form active immunotoxins was evaluated using an indirect assay of immunotoxin cytotoxicity. Monoclonal antibodies recognising differe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c238370d4aebcd8e60f9ae6f46731de3
https://pubmed.ncbi.nlm.nih.gov/1645577

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