Zobrazeno 1 - 10
of 11
pro vyhledávání: '"E Iu, Chirkova"'
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 55(6)
The experiments with unconscious cats and dogs have demonstrated that the calcium antagonist nimodipine has a profound anti-ischemic property. The drug reduces the average value of ST-segment elevation in multiple epicardial ECG leads, during acute m
Publikováno v:
Farmakologiia i toksikologiia. 54(3)
The experiments on different species of animals (mice, cats) showed the lack of parallelism between the antihypoxic and anti-ischemic effects of pharmacological agents. Of four studied antihypoxic agents (lithium oxybutyrate, piracetam, glyo-6, a der
Publikováno v:
Farmakologiia i toksikologiia. 54(3)
The effect of vasocyclin (prostacyclin) on the blood supply, activity and functional state of the intact and ischemic myocardium was studied in experiments on anesthetized cats. The drug (100, 300 and 500 mg/kg/min) was shown to produce a dose-depend
Publikováno v:
Farmakologiia i toksikologiia. 53(2)
In experiments on anesthetized cats with acute occlusion of the coronary artery followed by its reperfusion antihypoxants piracetam, lithium hydroxybutyrate and pyrid oxynyl-glyoxylate (glyo-6) were shown to stabilize the contractile and pumping func
Publikováno v:
TSitologiia i genetika. 21(3)
During "stationary phase ageing" of cultured Chinese hamster cells (B11dii-FAF28 line, 2372a clone), i. e. while decreasing the proliferation rate and in the stationary growth phase the frequency of spontaneous sister chromatid exchanges (SCE) progre
Publikováno v:
Tsitologiia. 27(8)
On the basis of the Verhulst-Pearl equation, a model of cultured cell growth kinetics is devised. Analysing both authors' and literature data, a possibility was shown to use the model for description of growth kinetics of different cultured cell type
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 101(4)
Accumulation of DNA-protein crosslinks during "stationary phase ageing" (i.e. with the increase of non-proliferating period) of cultured transformed Chinese hamster cells and normal embryonic diploid human fibroblasts was determined by the improved m
Publikováno v:
Tsitologiia. 29(3)
With the help of a previously devised model of cultured cell growth kinetics it was shown that the "plateau" level on the growth curve of human embryo diploid fibroblasts increased, if the cells were grown with Epigid geroprotector-antioxidant (equal
Publikováno v:
Tsitologiia. 26(8)
A gradual accumulation of the alkali-labile sites in DNA of cultured Chinese hamster cells during "stationary phase ageing" was shown by ultracentrifugation in alkaline sucrose gradients. A possibility is discussed of using the stationary phase mamma
Publikováno v:
TSitologiia i genetika. 19(2)
"Stationary phase ageing" of cultured Chinese hamster cells (when proliferation rate decreases and in the stationary growth phase) produces an increase in the frequency of spontaneous sister chromatid exchanges (SCE). Thiophosphamide-induced (24 h) f