EVpedia: a community web portal for extracellular vesicles research

Autor: D Kim, J Lee, S Kim, D Choi, Y Yoon, J Kim, G Go, D Nhung, K Hong, S Jang, K Park, O Kim, H Park, J Seo, E Aikawa, M Baj-Krzyworzeka, B Van, M Belting, L Blanc, V Bond, A Bongiovanni, F Borras, L Buee, E Buzas, Sim, Lesley, A Clayton, E Cocucci, C Dela, D Desiderio, V Di, K Ekstrom, J Falcon-Perez, C Gardiner, B Giebel, Greening, David, J Gross, D Gupta, A Hendrix, Hill, Andrew, M Hill, E Hoen, D Hwang, J Inal, M Jagannadham, M Jayachandran, Y Jee, M Jorgensen, K Kim, Y Kim, T Kislinger, C Lasser, D Lee, H Lee, L Van, T Lener, M Liu, J Lotvall, A Marcilla, Mathivanan, Suresh, A Moeller, J Morhayim, F Mullier, I Nazarenko, R Nieuwland, D Nunes, K Pang, J Park, T Patel, G Pocsfalvi, P Del, U Putz, M Ramirez, M Rodrigues, T Roh, F Royo, S Sahoo, R Schiffelers, S Sharma, P Siljander, Simpson, Richard, C Soekmadji, P Stahl, A Stensballe, E Stepien, H Tahara, A Trummer, H Valadi, L Vella, S Wai, K Witwer, M Yanez-Mo, H Youn, R Zeidler, Y Gho

© The Author 2014. Published by Oxford University Press. All rights reserved. Motivation: Extracellular vesicles (EVs) are spherical bilayered proteolipids, harboring various bioactive molecules. Due to the complexity of the vesicular nomenclatures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::281a28d308442bd321b09712beab5fc0

Transport of microorganisms into cellulose nanofiber mats

Autor: Raghuram Thyagarajan, H. F. Yeung, Jessica D. Schiffman, M. E. Hoen, Katrina A. Rieger, David M. Ford

Publikováno v: RSC Advances. 6:24438-24445

Nanofiber mats hold potential in numerous applications that interface with microorganisms. However, a fundamental study that quantifies the transport of microorganisms into three-dimensional microenvironments, such as nanofiber mats, has not yet been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::43178788616614ee6c7688456d1516b2
https://doi.org/10.1039/c6ra01394e

Anti-PEG antibodies alter the mobility and biodistribution of densely PEGylated nanoparticles in mucus

Autor: Qi Yang, Kenetta L. Nunn, Steve R. Roffler, Timothy E. Hoen, Ying Ying Wang, Richard A. Cone, Justin D. McCallen, Samuel K. Lai, Sumon Chattopadhyay, Christine E. Henry, Holly A. Schroeder, Laura M. Ensign, Thomas R. Moench, Thuy Hoang

Publikováno v: Acta biomaterialia. 43

Antibodies that specifically bind polyethylene glycol (PEG) can lead to rapid elimination of PEGylated therapeutics from the systemic circulation. We have recently shown that virus-binding IgG can immobilize viruses in mucus via multiple low-affinity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd410ac905b915f81a621d722cfa8b6
https://pubmed.ncbi.nlm.nih.gov/27424083

Contraceptive testing of vaginal agents in rabbits

Autor: Timothy E. Hoen, Philip E. Castle, Kevin J. Whaley, Richard A. Cone

Publikováno v: Contraception. 58:51-60

Development of new vaginal products, such as microbiocides and contraceptives, requires in vivo testing of their effect on fertility. Rabbits, unlike smaller laboratory animals such as rats and mice, which inseminate in the uterus, inseminate vaginal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f495e8d8b7465f1df36b209b106af055
https://doi.org/10.1016/s0010-7824(98)00059-6

Mucus-Penetrating Nanoparticles for Vaginal Drug Delivery Protect Against Herpes Simplex Virus

Autor: Terence A. Tse, Benjamin C. Tang, Timothy E. Hoen, Laura M. Ensign, Ying Ying Wang, Richard A. Cone, Justin Hanes

Publikováno v: Science Translational Medicine. 4

Incomplete coverage and short duration of action limit the effectiveness of vaginally administered drugs, including microbicides for preventing sexually transmitted infections. We investigated vaginal distribution, retention, and safety of nanopartic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d77df5c63943864a88b8956cef5fe6
https://doi.org/10.1126/scitranslmed.3003453