Zobrazeno 1 - 10
of 170
pro vyhledávání: '"E Helene Sage"'
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53202 (2013)
Secreted protein, acidic and rich in cysteine (SPARC) has been described as a counteradhesive matricellular protein with a diversity of biological functions associated with morphogenesis, remodeling, cellular migration, and proliferation. We have pro
Externí odkaz:
https://doaj.org/article/3fd9985b888b46398f2b1f05b74b206b
Autor:
Li-Fong Seet, Roseline Su, V A Barathi, Wing Sum Lee, Rebekah Poh, Yee Meng Heng, Ed Manser, Eranga N Vithana, Tin Aung, Matt Weaver, E Helene Sage, Tina T Wong
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9415 (2010)
Glaucoma is a disease frequently associated with elevated intraocular pressure that can be alleviated by filtration surgery. However, the post-operative subconjunctival scarring response which blocks filtration efficiency is a major hurdle to the ach
Externí odkaz:
https://doaj.org/article/e93f3dfc7c0d46fe9a9bcea67ed39746
Autor:
Irene Esposito, Hany Kayed, Shereen Keleg, Thomas Giese, E. Helene Sage, Peter Schirmacher, Helmut Friess, Jörg Kleeff
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 1, Pp 8-17 (2007)
SPARC-like protein 1 (SPARCL1), a member of the SPARC family, is downregulated in various tumors. In the present study, the expression and localization of SPARCL1 were analyzed in a wide range of nontumorous and neoplastic pancreatic tissues by quant
Externí odkaz:
https://doaj.org/article/c76b1fe1830f49439b464dbbb5b41e6d
Publikováno v:
Matrix biology : journal of the International Society for Matrix Biology
The concept of a matricellular protein was first proposed by Paul Bornstein in the mid-1990s to account for the non-lethal phenotypes of mice with inactivated genes encoding thrombospondin-1, tenascin-C, or SPARC. It was also recognized that these ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d4936bf7420bad06bec80a98ff7ce28
https://doi.org/10.1016/j.matbio.2014.07.005
https://doi.org/10.1016/j.matbio.2014.07.005
Autor:
E. Helene Sage, Sandra A. Rempel, Gail Workman, Matthew S. Weaver, Chad R. Schultz, Nancy Lemke
Publikováno v:
Journal of Cellular Biochemistry. 112:3093-3102
The matricellular SPARC-family member hevin (Sparc-like 1/SPARCL-1/SC1/Mast9) contributes to neural development and alters tumor progression in a range of mammalian models. Based on sequence similarity, we hypothesized that proteolytic digestion of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363992dcc86c2762f63bd2655d5544a1
https://doi.org/10.1002/jcb.23235
https://doi.org/10.1002/jcb.23235
Autor:
Gail Workman, E. Helene Sage
Publikováno v:
Journal of Cellular Biochemistry. 112:1003-1008
SPARC (osteonectin/BM-40), a secreted matricellular protein that promotes cellular deadhesion and motility in wound healing, carcinogenesis, and inflammation, binds to the scavenger receptor stabilin-1 in alternatively activated macrophages and under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4dea503f2c4ad2a1c0bb67c3c534a71
https://doi.org/10.1002/jcb.23015
https://doi.org/10.1002/jcb.23015
Publikováno v:
Spine. 36:95-102
Study design Secreted Protein, Acidic, and Rich in Cysteine (SPARC)-null mice were examined for behavioral signs of chronic low back and/or radicular pain. Objective to assess SPARC-null mice as an animal model of chronic low back and/or radicular pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f40e18e5bf122359f07546c5e9cdd5b
https://doi.org/10.1097/brs.0b013e3181cd9d75
https://doi.org/10.1097/brs.0b013e3181cd9d75
Autor:
Angela M. B. Collie, Robert B. Vernon, Pauli Puolakkainen, Patrick S. Stayton, Buddy D. Ratner, E. Helene Sage, Paige C. S. Bota
Publikováno v:
Journal of Biomedical Materials Research Part A. :649-657
The effect of biomaterial topography on healing in vivo and monocyte/macrophage stimulation in vitro was assessed. A series of expanded polytetrafluoroethylene (ePTFE) materials were characterized by increasing average intranodal distance of 1.2 µm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145ff1c29cbb3e3b249cfb4caf2fe2a3
https://doi.org/10.1002/jbm.a.32893
https://doi.org/10.1002/jbm.a.32893
Publikováno v:
Connective Tissue Research. 52:99-108
Secreted protein, acidic and rich in cysteine (SPARC), a matricellular protein, modulates extracellular matrix assembly and turnover in many physiological processes. SPARC-null mice exhibit an increased accumulation of adipose tissue. To distinguish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fbcf384e3357a5f1a58fcf4b18c43d4
https://doi.org/10.3109/03008207.2010.483747
https://doi.org/10.3109/03008207.2010.483747
Autor:
Srinivas Mamidi, E. Helene Sage, Vladimir Riabov, Gail Workman, Elisabeth Kremmer, Sergij Goerdt, Christina Schmuttermaier, Alexei Gratchev, Jingjing Zhang, Sirpa Jalkanen, Liis Krusell, Julia Kzhyshkowska
Publikováno v:
Molecular and Cellular Biology. 29:6097-6105
Stabilin-1 is a unique scavenger receptor that combines endocytic and intracellular sorting functions in macrophages. Stabilin-1 mediates the endocytosis of acetylated low-density lipoprotein (acLDL), SPARC, and growth hormone family member placental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93480e87235d7f0b45d1158383397a58
https://doi.org/10.1128/mcb.00505-09
https://doi.org/10.1128/mcb.00505-09