Zobrazeno 1 - 10
of 83
pro vyhledávání: '"E H Sage"'
Autor:
Peter O'Dwyer, E H Sage, David A. Roberts, G Workman, Steven W. Johnson, S Biade, Jonathan Schick, M Marinucci, Virginia A. LiVolsi
Publikováno v:
British Journal of Cancer
There is currently a lack of reliable diagnostic and prognostic markers for ovarian cancer. We established gene expression profiles for 120 human ovarian tumours to identify determinants of histologic subtype, grade and degree of malignancy. Unsuperv
Publikováno v:
Trends in Cardiovascular Medicine. 11:32-37
In the last decade, numerous studies have emphasized the important functions that matricellular proteins subserve during angiogenesis, wound healing, and the maintenance of organ and tissue integrity. Matricellular proteins are defined as a group of
Autor:
Krishnan Radhakrishnan, Katherine E. Elliott, John I. Clark, E H Sage, Andrew G. Farr, Patricia Parsons-Wingerter
Publikováno v:
Microvascular Research. 59:221-232
Quantitative analysis of vascular generational branching demonstrated that transforming growth factor-beta1 (TGF-beta1), a multifunctional cytokine and angiogenic regulator, strongly inhibited angiogenesis in the arterial tree of the developing quail
Publikováno v:
Journal of Cellular Biochemistry. 74:152-167
Secreted protein acidic and rich in cysteine (SPARC) is a matricellular protein that inhibits cellular adhesion and proliferation. In this study, we report the detection of SPARC in the interphase nuclei of embryonic chicken cells in vivo. Differenti
Autor:
George Jerums, E H Sage, Darren J. Kelly, Alison J. Cox, Jennifer L. Wilkinson-Berka, Mark E. Cooper, Richard E Gilbert
Publikováno v:
Connective Tissue Research. 40:295-303
Secreted protein acidic and rich in cysteine (SPARC) is a secreted glycoprotein protein which modulates cell shape and cell-matrix interactions and has been implicated in the regulation of angiogenesis, vascular permeability and cataract formation. I
Publikováno v:
Journal of Biological Chemistry. 273:29635-29640
SPARC (secreted protein, acidic and rich in cysteine) is a matricellular protein that modulates cell adhesion and proliferation and is thought to function in tissue remodeling and angiogenesis. In this study, we demonstrate that SPARC inhibits DNA sy
Publikováno v:
Journal of Cellular Biochemistry. 70:70-83
Transforming growth factor-beta1 (TGF-beta1) regulates a variety of cellular functions. In several types of cells, for example, it acts as a growth inhibitor and an inducer of apoptotic cell death. Although one of the important modulators in retinal
Publikováno v:
Journal of Histochemistry & Cytochemistry. 46:3-10
SPARC (secreted protein, acidic and rich in cysteine)/osteonectin is a matricellular, counteradhesive glycoprotein that disrupts cell-matrix interactions, interacts with growth factors and components of extracellular matrix, and modulates the cell cy
Publikováno v:
Nature Biotechnology. 15:581-585
Human SPARC (secreted protein acidic and rich in cysteine), an extracellular matrix protein containing 14 cysteine residues, was found to partition equally between soluble and insoluble cellular fractions when overexpressed in the Escherichia coli cy
Publikováno v:
Biochemical Journal. 324:311-319
Heparin-binding forms of vitronectin, a multifunctional adhesive glycoprotein, are associated with the extracellular matrix (ECM) at different locations in the body and serve to promote cell adhesion and the regulation of pericellular proteolysis at