Zobrazeno 1 - 10 of 59 pro vyhledávání: '"E H Ohlstein"'
1
Antisense Oligonucleotides to the P65 Subunit of NF-κb Inhibit Human Vascular Smooth Muscle Cell Adherence and Proliferation and Prevent Neointima Formation in Rat Carotid Arteries
Autor: E. H. Ohlstein, Tian-Li Yue, M. V. Autieri, G. Z. Ferstein
Publikováno v: Biochemical and Biophysical Research Communications. 213:827-836
Neointima formation associated with vascular restenosis is a complex local inflammatory process actively involving the major cellular component of the atherosclerotic lesion, the vascular smooth muscle cell. NF-kB is a pleotrophic transactivator of a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b67becb214e243bb5812e2254ebe5a
https://doi.org/10.1006/bbrc.1995.2204
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5
Palosuran inhibits binding to primate UT receptors in cell membranes but demonstrates differential activity in intact cells and vascular tissues
Autor: D J, Behm, J J, McAtee, J W, Dodson, M J, Neeb, H E, Fries, C A, Evans, R R, Hernandez, K D, Hoffman, S M, Harrison, J M, Lai, C, Wu, N V, Aiyar, E H, Ohlstein, S A, Douglas
Publikováno v: British journal of pharmacology. 155(3)
The recent development of the UT ligand palosuran (1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea sulphate salt) has led to the proposition that urotensin-II (U-II) plays a significant pathological role in acute and c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9940b321f206152091724b5bba433860
https://pubmed.ncbi.nlm.nih.gov/18587423
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6
Dopamine-1 receptors in rat proximal convoluted tubule: regulation by intrarenal dopamine
Autor: E. H. Ohlstein, S. Kinoshita, R. A. Felder
Publikováno v: American Journal of Physiology-Renal Physiology. 258:F1068-F1074
Dopamine (DA) is synthesized in the renal proximal convoluted tubule (PCT) and may act as a paracrine substance at tubular DA-1 receptors to decrease sodium transport. Although DA-1 receptors have been identified in rabbit renal PCT by use of nonsele
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba1df1a3194bf237748599e02ad2151
https://doi.org/10.1152/ajprenal.1990.258.4.f1068
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7
Effect of endothelin on cortical microvascular perfusion in rats
Autor: R N Willette, G Feuerstein, C F Sauermelch, E H Ohlstein, M Ezekiel
Publikováno v: Stroke. 21:451-458
We used laser-Doppler flowmetry to study the effects of endothelin-1 on local cortical microvascular perfusion and resistance in 29 pentobarbital-anesthetized rats. Intravenous administration of 10-300 pmol endothelin-1 reduced arterial blood pressur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2f8751dc15d95234734354739a892c
https://doi.org/10.1161/01.str.21.3.451
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8
Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia
Autor: F C, Barone, E A, Irving, A M, Ray, J C, Lee, S, Kassis, S, Kumar, A M, Badger, J J, Legos, J A, Erhardt, E H, Ohlstein, A J, Hunter, D C, Harrison, K, Philpott, B R, Smith, J L, Adams, A A, Parsons
Publikováno v: Medicinal research reviews. 21(2)
Mitogen-activated protein kinases (MAPKs) are involved in many cellular processes. The stress-activated MAPK, p38, has been linked to inflammatory cytokine production and cell death following cellular stress. Here, we demonstrate focal ischemic strok
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8381bbf219be5bd30f7d497ae7a99396
https://pubmed.ncbi.nlm.nih.gov/11223862
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9
SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia
Autor: F C, Barone, E A, Irving, A M, Ray, J C, Lee, S, Kassis, S, Kumar, A M, Badger, R F, White, M J, McVey, J J, Legos, J A, Erhardt, A H, Nelson, E H, Ohlstein, A J, Hunter, K, Ward, B R, Smith, J L, Adams, A A, Parsons
Publikováno v: The Journal of pharmacology and experimental therapeutics. 296(2)
The stress-activated mitogen-activated protein kinase (MAPK) p38 has been linked to the production of inflammatory cytokines/mediators/inflammation and death/apoptosis following cell stress. In these studies, a second-generation p38 MAPK inhibitor, S
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::678f01db509d528b1d463f0edc413a91
https://pubmed.ncbi.nlm.nih.gov/11160612
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10
Vascular and Cardiac Effects of Endothelin
Autor: S. A. Douglas, E. H. Ohlstein
Publikováno v: Endothelin and Its Inhibitors ISBN: 9783642632372
Endothelin (ET)-1, the most potent mammalian vasoconstrictor identified to date, was originally characterized as a peptide capable of producing contractile responses that were both sustained and extremely resistant to wash-out (Yanagisawa et al. 1988
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::93098c187bb404b2c40c56bd5046b95e
https://doi.org/10.1007/978-3-642-56899-2_16
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