Zobrazeno 1 - 10
of 33
pro vyhledávání: '"E H, Sasso"'
Autor:
M. S. Jurgens, M. Safy-Khan, M. J. H. de Hair, J. W. J. Bijlsma, P. M. J. Welsing, J. Tekstra, F. P. J. G. Lafeber, E. H. Sasso, J. W. G. Jacobs, on behalf of the Society for Rheumatology research Utrecht
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-9 (2020)
Abstract Objectives The CAMERA-II trial compared two tight-control, treat-to-target strategies, initiating methotrexate with prednisone (MTX+pred) or MTX with placebo (MTX+plac), in early RA-patients. The multi-biomarker disease activity (MBDA) blood
Externí odkaz:
https://doaj.org/article/56fda2b3974a492dbf353dccefa2737e
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-12 (2020)
Abstract Background Reliable assessment of remission is important for the optimal management of rheumatoid arthritis (RA) patients. In this study, we used the multi-biomarker disease activity (MBDA) test to explore the role of biomarkers in predictin
Externí odkaz:
https://doaj.org/article/96eca4db5c50437a84c2e0c6c36047ee
Autor:
DoQuyen Huynh, John Temple, P S Eastman, A. Kavanaugh, David L. Boyle, Joshua Hillman, E H Sasso, R Bolce, F Qureshi, T A Boyd
Publikováno v:
Expert Review of Clinical Immunology. 16:335-341
Objective: To assess the correlation of serum protein biomarkers with disease activity across different domains of psoriatic arthritis (PsA).Material and methods: A cross-sectional cohort of 45 adult patients with PsA fulfilling the classification fo
Additional file 2: Supplementary Table 2. Time-integrated biomarker concentrations and MBDA scores in the groups with persistent disease activity, intermittent remission and sustained remission over 12 months. Comparison of time-integrated (ti) value
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f308309b544c147e81a98d9763e020
Autor:
O G, Segurado, E H, Sasso
Publikováno v:
Clinical and experimental rheumatology. 32(5 Suppl 85)
Quantitative and regular assessment of disease activity in rheumatoid arthritis (RA) is required to achieve treatment targets such as remission and to optimize clinical outcomes. To assess inflammation accurately, predict joint damage and monitor tre
Publikováno v:
Journal of the European Academy of Dermatology and Venereology : JEADV. 27(5)
REVEAL was a 52-week study of adalimumab for moderate to severe psoriasis. At Week 33, adalimumab-treated patients with sustained responses (PASI ≥75 at Weeks 16 and 33) were re-randomized to receive adalimumab or placebo. Subsequently, they could
Publikováno v:
The British journal of dermatology. 165(2)
CHAMPION was a phase III trial that compared adalimumab with methotrexate and placebo for chronic plaque psoriasis.To determine the relationship between methotrexate dosing and improvement in psoriasis for patients in CHAMPION.Methotrexate-treated pa
Publikováno v:
The Journal of Immunology. 150:2858-2868
To investigate the organization and evolution of VH gene segments, we characterized the elements belonging to the VH4 gene family from the germline of a single subject. One hundred sixty VH4-carrying lambda-phage clones were isolated from a genomic l
Publikováno v:
The Journal of Immunology. 149:3741-3752
In B cell precursors developing in fetal lymphopoietic tissue, the selection of VH, DH, and JH gene segments for initial H chain gene assembly is biased. The present study was designed to determine whether these biases persist in fully developed huma
Publikováno v:
Proceedings of the National Academy of Sciences. 89:10430-10434
The adult repertoire of antibody specificities is acquired in a developmentally programmed fashion that, in mouse and man, parallels the ordered rearrangement of a limited number of germ-line heavy chain variable region (VH) gene segments during deve