Zobrazeno 1 - 10 of 11 pro vyhledávání: '"E H, Kovnar"'
1
Multiple causes of cerebrovascular events in children with tumors of the parasellar region
Autor: M S, Rudoltz, W F, Regine, J W, Langston, R A, Sanford, E H, Kovnar, L E, Kun
Publikováno v: Journal of neuro-oncology. 37(3)
Cerebrovascular arterial occlusion is a rare but devastating event causing long-term morbidity in children with tumors in the parasellar region. While usually associated with radiation therapy, there are a variety of host, tumor and treatment factors
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bdbce1c3b3c28958bb26d542f0b5709b
https://pubmed.ncbi.nlm.nih.gov/9524083
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2
A phase II evaluation of thiotepa in pediatric central nervous system malignancies
Autor: R L, Heideman, R J, Packer, G H, Reaman, J C, Allen, B, Lange, M E, Horowitz, S M, Steinberg, A, Gillespie, E H, Kovnar, F M, Balis
Publikováno v: Cancer. 72(1)
Both thiotepa and its active metabolite, tepa, efficiently cross the blood-brain barrier. After intravenous administration, the cerebrospinal fluid concentrations achieved are nearly identical to those in plasma. This provides a strong rationale for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::73d1299e02ea86634667c7c6dd5b8713
https://pubmed.ncbi.nlm.nih.gov/8508417
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3
A phase I study of ifosfamide given on alternate days to treat children with brain tumors
Autor: C B, Pratt, E C, Douglass, E H, Kovnar, R, Heideman, L, Kun, L, Avery, S J, Kellie
Publikováno v: Cancer. 71(11)
Ifosfamide with Mesna, given every other day over a 5-day period, was evaluated in 20 children with recurrent or progressive primary brain tumors.The patients were assigned to dosage cohorts separated on the basis of prior exposure to cisplatin (n =
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5aed43a83d05898f8ab9dea0a0da2171
https://pubmed.ncbi.nlm.nih.gov/8490915
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4
Neuraxis dissemination in pediatric brain tumors. Response to preirradiation chemotherapy
Autor: S J, Kellie, E H, Kovnar, L E, Kun, M E, Horowitz, R L, Heideman, E C, Douglass, J W, Langston, R A, Sanford, J J, Jenkins, D L, Fairclough
Publikováno v: Cancer. 69(4)
Of 29 consecutive children treated for malignant primary tumors of the central nervous system (CNS) at this institution, postoperative examination showed radiographic or cytologic evidence of neuraxis dissemination in 10 (34%). Given the historically
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2cd5189d785ffb66cfca68444961c92d
https://pubmed.ncbi.nlm.nih.gov/1735073
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5
Primary extracranial neuroblastoma with central nervous system metastases characterization by clinicopathologic findings and neuroimaging
Autor: S J, Kellie, F A, Hayes, L, Bowman, E H, Kovnar, J, Langston, J J, Jenkins, W J, Pao, R, Ducos, A A, Green
Publikováno v: Cancer. 68(9)
The authors report the clinicopathologic and neuroimaging findings in ten children with primary abdominal or thoracic neuroblastoma who relapsed in the central nervous system (CNS) without evidence of concurrent intracranial extension from adjacent b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d02124545be73a159f41944eae391b08
https://pubmed.ncbi.nlm.nih.gov/1913549
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6
Psychologic and Neurologic Function Following Treatment for Childhood Temporal Lobe Astrocytoma
Autor: L. E. Kun, J. Jeffrey Crisco, R. K. Mulhern, E. H. Kovnar, Williams Jm
Publikováno v: Journal of Child Neurology. 3:47-52
Seven school-aged children treated for temporal lobe astrocytomas with surgical resection and irradiation were prospectively tested to evaluate their intellectual, academic, personality, and neurologic status after therapy. At their most recent follo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a45f3319e4530c261337be43f3715fcb
https://doi.org/10.1177/088307388800300111
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7
Potentiation of ifosfamide neurotoxicity, hematotoxicity, and tubular nephrotoxicity by prior cis-diamminedichloroplatinum(II) therapy
Autor: M P, Goren, R K, Wright, C B, Pratt, M E, Horowitz, R K, Dodge, M J, Viar, E H, Kovnar
Publikováno v: Cancer research. 47(5)
We investigated the relationship between prior therapy and three distinct forms of toxicity that developed during ifosfamide administration (1.6 g/m2/day for 5 days) in 36 children with malignant solid tumors. Of ten therapies that were studied by mu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::87668f767e342dcd7b6560e54ccba7c7
https://pubmed.ncbi.nlm.nih.gov/3815347
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10
Serial neuropsychological studies of a child with acute lympho-blastic leukemia and subsequent glioblastoma multiforme
Autor: J. M. Williams, R. K. Mulhern, E. H. Kovnar, A L Wasserman, J Ochs
Publikováno v: Neurology. 36:1534-1534
A 10-year-old boy had a right posterior parietal glioblastoma 5 years after completing treatment for acute lymphoblastic leukemia. Interim findings included seizures, leukoencephalopathy, diffuse mineralizing micro-angiopathy, and abnormal changes in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732a96b8a909fc6c1d56560ffd929018
https://doi.org/10.1212/wnl.36.11.1534
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