Carboplatin-based doublet plus bevacizumab beyond progression versus carboplatin-based doublet alone in patients with platinum-sensitive ovarian cancer: a randomised, phase 3 trial

Autor: Giovanni Scambia, Daniela Sambataro, Coraline Dubot, Rossella Lauria, Francesco Raspagliesi, Patricia Pautier, Simona Frezzini, S Mammoliti, U De Giorgi, Ugo De Giorgi, C Sessa, Angiolo Gadducci, Isabelle Ray-Coquard, A Gadducci, Rémy Largillier, Francesco Perrone, Alessandra Bologna, Sandro Pignata, G Scambia, Elena Zafarana, E Breda, Florence Joly, R Largillier, Saverio Cinieri, C Pisano, Carmela Pisano, C Gallo, Frédéric Selle, Vanda Salutari, Cristiana Sessa, Aristotelis Bamias, F Joly, R Lauria, A Ardizzoia, Laure Favier, Nicoletta Colombo, D Sambataro, F Perrone, Domenica Lorusso, C Dubot, G Daniele, Emmanuel Guardiola, A Bamias, Gennaro Daniele, V Salutari, F Selle, S. Mammoliti, E Zafarana, P Pautier, M Orditura, Enrico Breda, A Bologna, E Guardiola, Michele Orditura, Ciro Gallo, L Favier, S Cinieri, N Colombo, I Ray-Coquard, S Frezzini, S Pignata, F Raspagliesi, Antonio Ardizzoia

Background: Bevacizumab is approved in combination with chemotherapy for the treatment of ovarian cancer, either in first-line therapy or for patients with recurrent disease not previously treated with the same drug. We aimed to test the value of con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5cf8324eaa8e8e6577f2c091ed2f66
http://hdl.handle.net/11591/461646

Abstract P1-13-09: Withdrawn

Autor: PA Fasching, Christos Sotiriou, J-Y Pierga, M.J. Piccart, Tanja Fehm, Sabine Riethdorf, M Ignatiadis, Wolfgang Janni, E. Brain, Charlotte Proudhon, Konstantinos Tryfonidis, Saskia Litière, Brigitte Rack, Ralf Lorenz, K Aalders, Klaus Pantel, Françoise Rothé, Peter Vuylsteke, E. Guardiola, Helmut Forstbauer

Publikováno v: Cancer Research. 78:P1-13

This abstract was withdrawn by the authors.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25b7dbf3c8712f8a086ee5eab629a160
https://doi.org/10.1158/1538-7445.sabcs17-p1-13-09

Abstract P2-05-10: UCBG 2-14: A prospective multicenter non-randomized trial evaluating the effect of EndoPredict® (EPclin®) clinico-genomic test on treatment decision making among patients with intermediate clinical risk

Autor: Olfa Derbel, F Kwiatkovski, Veronique Girre, Christelle Jouannaud, A Le Rol, N Quenel-Tueux, E. Guardiola, J.P. Jacquin, Alain Lortholary, C Foa, Stéphanie Catala, Marianne Leheurteur, S. Delaloge, J. Grenier, Christine Levy, Lionel Uwer, Jérôme Lemonnier, Frédérique Penault-Llorca

Publikováno v: Cancer Research. 77:P2-05

Background: Genomic tests can identify ER-positive Her2-negative localized breast cancer (BC) patients (pts) who may not drive any benefit from adjuvant chemotherapy (CT). Several genomic tests have reached a high level of analytical and clinical val

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::570d205ad1d5b265cd85ce6ee0dddc1d
https://doi.org/10.1158/1538-7445.sabcs16-p2-05-10

6 months versus 12 months of adjuvant trastuzumab in early breast cancer (PHARE): final analysis of a multicentre, open-label, phase 3 randomised trial

Autor: Xavier Pivot, Gilles Romieu, Marc Debled, Jean-Yves Pierga, Pierre Kerbrat, Thomas Bachelot, Alain Lortholary, Marc Espié, Pierre Fumoleau, Daniel Serin, Jean-Philippe Jacquin, Christelle Jouannaud, Maria Rios, Sophie Abadie-Lacourtoisie, Laurence Venat-Bouvet, Laurent Cany, Stéphanie Catala, David Khayat, Laetitia Gambotti, Iris Pauporté, Celine Faure-Mercier, Sophie Paget-Bailly, Julie Henriques, Jean Marie Grouin, C Piprot, L Cals, L Chaigneau, F Demarchi, T N'Guyen, U Stein, C Villanueva, JL Bréau, AK Chouahnia, P Saintigny, F Boué, P deSaint-Hilaire, I Guimont, N Grossat, B Valenza, E Lévy, J Médioni, C Delbaldo, J Grenier, D Pouessel, S Lavau-Denès, C Falandry, C Fournel-Fédérico, G Freyer, S Tartas, V Trillet-Lenoir, F Bons, G Auclerc, S Chièze, N Raban, C Tournigand, S Trager-Maury, G Bousquet, C Cuvier, S Giacchetti, A Hocini, C LeMaignan, JL Misset, D Avenin, C Beerblock, J Gligorov, P Rivera, H Roché, P Bougnoux, N Hajjaji, O Capitain, R Delva, P Maillart, P Soulié, H Bonnefoi, M Durand, N Madranges, L Mauriac, P Chollet, AF Dillies, X Durando, JP Ferrière, C Mouret-Reynier, JM Nabholtz, I Van Praagh, P Cottu, V Diéras, A Durieux, M Galotte, V Girre, S Henry, I Iurisci, M Jouve, V Laurence, L Mignot, S Piperno-Neumann, P Tresca, B Coudert, E Ferrant, F Mayer, AC Vanneuville, J Bonneterre, V Servent, L Vanlemmens, P Vennin, JP Guastalla, P Biron, L Dupuy-Brousseau, L Lancry, I Ray-Coquard, P Rebattu, O Trédan, JM Extra, F Rousseau, C Tarpin, M Fabbro, E Luporsi, L Uwer, B Weber, D Berton-Rigaud, E Bourbouloux, M Campone, JM Ferrero, P Follana, R Largillier, V Mari, B Costa, H Curé, JC Eymard, N Jovenin, D Lebrun, J Meunier, G Yazbek, D Gedoin, B Laguerre, C Lefeuvre, E Vauléon, A Chevrier, C Guillemet, M Leheurteur, O Rigal, I Tennevet, C Veyret, E Brain, M Guiterrez, F Mefti-Lacheraf, T Petit, F Dalenc, L Gladieff, F André, S Delaloge, J Domont, J Ezenfis, M Spielmann, P Guillet, V Boulanger, J Provençal, L Stefani, C Alliot, D Ré, C Bellaiche-Miccio, G Boutan-Laroze, R Vanica, P Dion, G Sadki-Benaoudia, A Marti, AL Villing, B Slama, JL Dutel, S Nguyen, R Saad, O Arsène, Z Merad-Boudia, H Orfeuvre, J Egreteau, MJ Goudier, R Lamy, B Leduc, C Sarda, B Salles, C Agostini, I Cauvin, A Dufresne, M Mangold, S Lebouvier-Sadot, B Audhuy, JC Barats, S Cluet-Dennetière, D Zylberait, G Netter, L Gautier-Felizot, I Cojean-Zelek, A Plantade, S Vignot, E Guardiola, P Marti, I deHartingh, R Diab, A Dietmann, S Ruck, C Portois, S Oddou-Lagranière, F Campos-Gazeau, A Bourcier, F Priou, JF Geay, D Mayeur, P Gabez, R ElAmarti, M Combe, P Raichon-Patru, P Amsalhem, J Dauba, D Paraiso, F Guinet, B Duvert, M Litor, F Kara-Slimane, A Bichoffe, N Denizon, P Soyer, F Morvan, S Van-Hulst, L Vincent, C Alleaume, P Ibanez-Martin, A Youssef, Z Tadrist, E Carola, C Pourny, JF Toccanier, N Al-Aukla, K Mahour-Bacha, J Salvat, P Nouyrigat, S Clippe, MC Gouttebel, L Vedrine, G Clavreul, O Collard, D Mille, Y Goubely, R Hervé, S Kirscher, F Plat, V Delecroix, V Ligeza-Poisson, D Coeffic, D Fric, C Garnier, C Leyronnas, T Kreitman, E Teissier, P Martin, S Rohart deCordoue, C ElKouri, JF Ramée, C Laporte, O Bernard, T Altwegg, A Darut-Jouve, JP Dujols, F Darloy, C Giraud, V Pottier-Kyndt, N Achour, S Drony, M Moriceau, C Sarrazin, JC Legueul, J Mandet, D Besson, AC Hardy-Bessard, J Cretin, P Houyau, E Achille, D Genêt, H Thévenot, A Moran-Ribon, JM Pavlovitch, P Ardisson, I Moullet, B Couderc, V Fichet, F Burki, A Auliard, CB Levaché, P Cailleux, F Schaeffer, N Albin, D Sévin-Robiche, J Domas, S Ellis, P Montcuquet, GA Baumont, M Bégue, S Gréget, JL Ratoanina, A Vanoli, C Bielsa, M Bonichon-Lamichhane, D Jaubert, H Laharie-Mineur, L Alcaraz, E Legouffe, H Bourgeois, G Cartron, F Denis, O Dupuis, G Ganem, S Roche-Forestier, L Delzenne, E Chirat, JL Baticle, E Béguier, S Jacquot, E Janssen, H Lauché, A LeRol, JP Chantelard, GA L'Helgoualc'h, EC Antoine, A Kanoui, JF Llory, JM Vannetzel, J Vignoud, C Bruna, T Facchini, K Moutel-Corviole, A Voloch, A Ghoul, D Loiseau, N Barbet, N Dohollou, K Yakendji

Publikováno v: Lancet (London, England). 393(10191)

Summary Background In 2013, the interim analysis of the Protocol for Herceptin as Adjuvant therapy with Reduced Exposure (PHARE) trial could not show that 6 months of adjuvant trastuzumab was non-inferior to 12 months. Here, we report the planned fin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a38de46b67775457b35c99536d038418
https://pubmed.ncbi.nlm.nih.gov/31178155

[The scotomas as a metaphor in the work of Oliver Sacks]

Autor: J, Casas, E, Guardiola, Oliver, Sacks

Publikováno v: Revista de neurologia. 67(5)

The use of medical metaphors is common in the social discourse and in the media. However, the use by physicians themselves to define different concepts to the original meaning of the medical word is rare.To analyze the term «scotoma» in its metapho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0908762f2ed28b7dbc344fd1e0cc2c37
https://pubmed.ncbi.nlm.nih.gov/30047121